2,4-dichloro-5-fluoropyrimidine

Basic Information

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CAS Number

2927-71-1

Molecular Formula

C4HCl2FN2

Molecular Weight

166.97 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Specialty Chemicals UV Stabilizers

Agricultural Chemicals Pesticides Herbicides

Electronic Chemicals Semiconductor Materials Etchants

Basic Physical Properties

Physical State

White to Yellow Solid

Melting Point

37.0 to 41.0 deg-C

Boiling Point

80°C/16mmHg

Refractive Index

1.532

SMILES

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C1=C(C(=NC(=N1)Cl)Cl)F

InChI

InChI=1S/C4HCl2FN2/c5-3-2(7)1-8-4(6)9-3/h1H

InChIKey

WHPFEQUEHBULBW-UHFFFAOYSA-N

LogP

1.9224999999999999

Topological Polar Surface Area

25.78 Å²

Hydrogen Bond Donor/Acceptor

0 / 2

Complexity

103

Safety Information

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GHS Hazard Pictograms

H302

H314

Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H314 Causes severe skin burns and eye damage
Skin corrosion/irritation

Hazard Class

Class 8 Class 8

Sensitiveness

Moisture Sensitive

Synonyms & References

English

DTXSID00290702
AM20090386
NCIOpen2_000539
2,4-Dichloro-5-fluoropyrimidine
2927-71-1
D3374
C4HCl2FN2
2,6-DICHLORO-5-FLUOROPYRIMIDINE
5-fluoro-2,6-dichloropyrimidine
2.4-Dichloro-5-fluoropyrimidine
MFCD00233551
F2108-0226
5-fluoro-2,4-dichloro-pyrimidine
EN300-25797
GS-6791
5-fluoro-2,4-dichloropyrimidine
Z217688316
W-202221
2,4-Dichloro-5-fluoropyrmidine
NSC70442
FT-0699076
CS-W008648
NSC-70442
AC-2990
2 pound not4-Dichloro-5-fluoropyrimidine
2,4-dichloro-5-fluoro-pyrimidine
SCHEMBL190657
AKOS002665246
SY003504
2,4dichloro-5-fluoropyrimidine
FT-0630162

MDL Number

MFCD00233551

Customs Code

2933599090

FAQ

What is 2,4-dichloro-5-fluoropyrimidine (CAS: 2927-71-1)?

2,4-dichloro-5-fluoropyrimidine (CAS: 2927-71-1) is a halogenated pyrimidine derivative with the chemical formula C4H2Cl2FN2. It appears as a white crystalline solid, exhibits low solubility in water, and is soluble in polar organic solvents. This compound is characterized by its stability under normal conditions and is commonly used as an intermediate in organic synthesis due to its reactivity and structural versatility.

What are the main uses of 2,4-dichloro-5-fluoropyrimidine (CAS: 2927-71-1)?

2,4-dichloro-5-fluoropyrimidine (CAS: 2927-71-1) is primarily utilized in pharmaceutical research as a precursor for developing antiviral and anticancer drugs. It also finds applications in industrial chemistry for synthesizing dyes and agrochemicals. In research settings, it serves as a building block for creating novel compounds, leveraging its halogenated structure to facilitate further functionalization and chemical modifications.

Is 2,4-dichloro-5-fluoropyrimidine (CAS: 2927-71-1) safe?

2,4-dichloro-5-fluoropyrimidine (CAS: 2927-71-1) requires careful handling due to potential health hazards. It may cause irritation to the skin, eyes, and respiratory system upon exposure. Safety standards recommend using appropriate personal protective equipment (PPE), such as gloves and goggles, and working in a well-ventilated area. Long-term toxicity data is limited, but adherence to standard chemical safety protocols minimizes risks.

How should 2,4-dichloro-5-fluoropyrimidine (CAS: 2927-71-1) be stored?

2,4-dichloro-5-fluoropyrimidine (CAS: 2927-71-1) should be stored in a sealed, airtight container in a cool, dry place, away from light and incompatible substances. Maintain storage temperature between 2-8°C to ensure stability. Avoid exposure to moisture and high humidity levels. Always store in a well-ventilated area to prevent vapor accumulation, and follow guidelines for handling hazardous chemicals as per OSHA and EPA standards.