N-(2-{4-[(Cyclohexylcarbamoyl)sulfamoyl]phenyl}ethyl)-5-methyl-2-pyrazinecarboxamide | CAS No. 29094-61-9

N-(2-{4-[(Cyclohexylcarbamoyl)sulfamoyl]phenyl}ethyl)-5-methyl-2-pyrazinecarboxamide

Basic Information

CAS Number

29094-61-9

Molecular Formula

C21H27N5O4S

Molecular Weight

445.55 g/mol

AD

Basic Physical Properties

Melting Point

208-217°C

Density

1.34

Solubility

methanol: 1.9 mg/mL

Refractive Index

1.597

CC1=CN=C(C=N1)C(=O)NCCC2=CC=C(C=C2)S(=O)(=O)NC(=O)NC3CCCCC3

InChI

InChI=1S/C21H27N5O4S/c1-15-13-24-19(14-23-15)20(27)22-12-11-16-7-9-18(10-8-16)31(29,30)26-21(28)25-17-5-3-2-4-6-17/h7-10,13-14,17H,2-6,11-12H2,1H3,(H,22,27)(H2,25,26,28)

InChIKey

ZJJXGWJIGJFDTL-UHFFFAOYSA-N

LogP

2.0781199999999993

Topological Polar Surface Area

130.15 Ų

Hydrogen Bond Donor/Acceptor

3 / 9

Complexity

697

Safety Information

View Safety Information

Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation
H319 Causes serious eye irritation
Serious eye damage/eye irritation
H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Toxicity

LD50 in mice, rats (g/kg): >3, 1.2 i.p. (Ambrogi)

Synonyms & References

English

  • GLIPIZIDE [MI]
  • Glipizide 100 microg/mL in Acetonitrile
  • KBio3_000138
  • NCGC00015462-10
  • NCGC00261306-01
  • Q3108899
  • NSC 759120
  • GLIPIZIDE [EP MONOGRAPH]
  • Prestwick2_000131
  • HMS2093J09
  • NCGC00015462-23
  • Aldiab
  • HMS2233N11
  • HY-B0254
  • NCGC00015462-06
  • KBioSS_000069
  • NCGC00015462-08
  • Glucotrol
  • NCGC00015462-14
  • NCGC00016802-01
  • MLS001148176
  • Dipazide
  • N-(4-(beta-(5-Methylpyrazine-2-carboxamido)ethyl)benzenesulphonyl)-N'-cyclohexylurea
  • Glide
  • Glipizidum (INN-Latin)
  • LP00621
  • IDI1_033819
  • NSC-759120
  • HMS3259K12
  • Glucolip
  • Minidiab

MDL Number

MFCD00072159

Customs Code

2935009090

FAQ

What is N-(2-{4-[(Cyclohexylcarbamoyl)sulfamoyl]phenyl}ethyl)-5-methyl-2-pyrazinecarboxamide (CAS: 29094-61-9)?

N-(2-{4-[(Cyclohexylcarbamoyl)sulfamoyl]phenyl}ethyl)-5-methyl-2-pyrazinecarboxamide (CAS: 29094-61-9) is a complex organic compound containing a pyrazinecarboxamide ring and a sulfamoyl group attached to a cyclohexylcarbamoyl moiety. It is typically a solid at room temperature and exhibits solubility in polar organic solvents. Its molecular structure suggests potential applications in pharmaceutical research, particularly in drug development targeting metabolic or enzymatic pathways.

What are the main uses of N-(2-{4-[(Cyclohexylcarbamoyl)sulfamoyl]phenyl}ethyl)-5-methyl-2-pyrazinecarboxamide (CAS: 29094-61-9)?

This compound is primarily used in pharmaceutical research as an intermediate for developing drugs related to metabolic disorders or enzyme inhibition. Its unique structure, combining sulfamoyl and pyrazinecarboxamide functionalities, may also find applications in agrochemicals, materials science, and industrial chemical synthesis. It is valued for its potential to modulate biological activity in targeted therapies.

Is N-(2-{4-[(Cyclohexylcarbamoyl)sulfamoyl]phenyl}ethyl)-5-methyl-2-pyrazinecarboxamide (CAS: 29094-61-9) safe?

Safety of N-(2-{4-[(Cyclohexylcarbamoyl)sulfamoyl]phenyl}ethyl)-5-methyl-2-pyrazinecarboxamide (CAS: 29094-61-9) depends on exposure conditions. It may cause skin or eye irritation and should be handled with appropriate protective equipment. While not classified as highly toxic, it requires adherence to standard chemical safety protocols, including proper ventilation and storage. Always consult a safety data sheet (SDS) for detailed handling guidelines.

How should N-(2-{4-[(Cyclohexylcarbamoyl)sulfamoyl]phenyl}ethyl)-5-methyl-2-pyrazinecarboxamide (CAS: 29094-61-9) be stored?

Store N-(2-{4-[(Cyclohexylcarbamoyl)sulfamoyl]phenyl}ethyl)-5-methyl-2-pyrazinecarboxamide (CAS: 29094-61-9) in a cool, dry place (ideally 2-8°C), protected from light. Keep it in a sealed, airtight container to prevent moisture absorption and degradation. Avoid exposure to incompatible substances and ensure storage complies with chemical stability requirements to maintain efficacy and safety.

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