Login

2-[3,5-Bis(trifluoromethyl)phenyl]-N,2-dimethyl-N-[4-(2-methylphenyl)-6-(4-methyl-1-piperazinyl)-3-pyridinyl]propanamide | CAS No. 290297-26-6

2-[3,5-Bis(trifluoromethyl)phenyl]-N,2-dimethyl-N-[4-(2-methylphenyl)-6-(4-methyl-1-piperazinyl)-3-pyridinyl]propanamide

Basic Information

Chemical_Structure_Of
View in Editor

CAS Number

290297-26-6

Molecular Formula

C30H32F6N4O

Molecular Weight

578.6 g/mol

AD

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids
Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds
Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates
Fine Chemicals Dyes and Pigments Organic Dyes
Fine Chemicals Surfactants Anionic Surfactants
Fine Chemicals Specialty Chemicals UV Stabilizers
Agricultural Chemicals Pesticides Herbicides
Laboratory Chemicals Research Chemicals Biochemical Reagents

Basic Physical Properties

Boiling Point

597.4°C at 760 mmHg

SMILES

View in Editor

CC1=CC=CC=C1C2=CC(=NC=C2N(C)C(=O)C(C)(C)C3=CC(=CC(=C3)C(F)(F)F)C(F)(F)F)N4CCN(CC4)C

InChI

InChI=1S/C30H32F6N4O/c1-19-8-6-7-9-23(19)24-17-26(40-12-10-38(4)11-13-40)37-18-25(24)39(5)27(41)28(2,3)20-14-21(29(31,32)33)16-22(15-20)30(34,35)36/h6-9,14-18H,10-13H2,1-5H3

InChIKey

WAXQNWCZJDTGBU-UHFFFAOYSA-N

LogP

6.787020000000008

Topological Polar Surface Area

39.68000000000001 Ų

Hydrogen Bond Donor/Acceptor

0 / 5

Complexity

865

Safety Information

View Safety Information

Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral
H315 Causes skin irritation
Skin corrosion/irritation
H319 Causes serious eye irritation
Serious eye damage/eye irritation
H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

  • s4654
  • GLXC-15009
  • HY-16346
  • NS00040679
  • BENZENEACETAMIDE, N,.ALPHA.,.ALPHA.-TRIMETHYL-N-(4-(2-METHYLPHENYL)-6-(4-METHYL-1-PIPERAZINYL)-3-PYRIDINYL)-3,5-BIS(TRIFLUOROMETHYL)-
  • Benzeneacetamide, N,alpha,alpha-trimethyl-N-[4-(2-methylphenyl)-6-(4-methyl-1-piperazinyl)-3-pyridinyl]-3,5-bis(trifluoromethyl)-
  • N,alpha,alpha-Trimethyl-N-[4-(2-methylphenyl)-6-(4-methyl-1-piperazinyl)-3-pyridinyl]-3,5-bis(trifluoromethyl)-benzeneacetamide
  • MFCD25976831
  • RO-67-3189/000
  • DB09048
  • AKYNZEO CAPSULE COMPONENT NETUPITANT
  • 2-(3,5-bis(trifluoromethyl)phenyl)-N,2-dimethyl-N-(6-(4-methylpiperazin-1-yl)-4-(o-tolyl)pyridin-3-yl)propanamide
  • Z2037279612
  • 2-(3,5-bis(trifluoromethyl)phenyl)-N,2-dimethyl-N-(6-(4-methylpiperazin-1yl)-4-(o-tolyl)pyridin-3yl)propanamide
  • CCG-270121
  • Ro 67-31898/000
  • Netupitant
  • 2-[3,5-bis(trifluoromethyl)phenyl]-~{N},2-dimethyl-~{N}-[4-(2-methylphenyl)-6-(4-methylpiperazin-1-yl)pyridin-3-yl]propanamide
  • 290297-26-6
  • CID6451149
  • FT-0699740
  • CID 6451149
  • 2-(3,5-bis(trifluoromethyl)phenyl)-N,2-dimethyl-N-(6-(4-methylpiperazin-1-yl)-4-o-tolylpyridin-3-yl)propanamide
  • Benzeneacetamide, N,alpha,alpha-trimethyl-N-(4-(2-methylphenyl)-6-(4-methyl-1-piperazinyl)-3-pyridinyl)-3,5-bis(trifluoromethyl)-
  • SCHEMBL445804
  • Netupitant [USAN:INN]
  • Ro 67-31898
  • NETUPITANT [MI]
  • 7732P08TIR
  • Ro 67-3189/000
  • GTPL5742

MDL Number

MFCD25976831

FAQ

What regulatory guidelines apply to 2-[3,5-Bis(trifluoromethyl)phenyl]-N,2-dimethyl-N-[4-(2-methylphenyl)-6-(4-methyl-1-piperazinyl)-3-pyridinyl]propanamide (CAS: 290297-26-6)?
This compound falls under regulatory guidelines such as REACH in the EU and the Globally Harmonized System of Classification and Labelling of Chemicals (GHS). It is recommended to consult the latest REACH documentation for specific requirements, including hazard classification, SDS preparation, and safety data. Additionally, the FDA and EPA may have specific regulations for its use, handling, and disposal in the United States.

Are there alternatives to 2-[3,5-Bis(trifluoromethyl)phenyl]-N,2-dimethyl-N-[4-(2-methylphenyl)-6-(4-methyl-1-piperazinyl)-3-pyridinyl]propanamide (CAS: 290297-26-6) in synthesis?
There are several alternatives that can be considered in the synthesis, such as using 2-[3,5-dichlorophenyl]-N,2-dimethyl-N-[4-(2-methylphenyl)-6-(4-methyl-1-piperazinyl)-3-pyridinyl]propanamide or similar compounds with similar functional groups. Further exploration of synthetic routes can include the use of analogous compounds with slight modifications in the substituents to achieve similar properties.

What is the market or research trend for 2-[3,5-Bis(trifluoromethyl)phenyl]-N,2-dimethyl-N-[4-(2-methylphenyl)-6-(4-methyl-1-piperazinyl)-3-pyridinyl]propanamide (CAS: 290297-26-6)?
The market trend for this compound is driven by its use in pharmaceutical and research applications, particularly in the development of potent and selective inhibitors. Research is focusing on its potential in treating various diseases, including cancer. The compound is also being explored for its pharmacological properties, such as its ability to modulate specific protein targets.

How should waste containing 2-[3,5-Bis(trifluoromethyl)phenyl]-N,2-dimethyl-N-[4-(2-methylphenyl)-6-(4-methyl-1-piperazinyl)-3-pyridinyl]propanamide (CAS: 290297-26-6) be handled?
Waste containing this compound should be collected in appropriate containers and disposed of according to local regulations. Incineration is a common method for disposal, ensuring complete destruction of the compound to minimize environmental impact. For professional disposal, contact hazardous waste management services to ensure compliance with all environmental protection precautions and regulatory requirements.

Related Compounds

You might also like

Compound Q&A

What is 6-Methyl-7-oxabicyclo[4.1.0]heptan-2-one (CAS: 21889-89-4)?

6-Methyl-7-oxabicyclo[4.1.0]heptan-2-one is a cyclic ketone with a molecular for...

21889-89-46-Methyl-7-oxabicycl...
Compound Q&A

What is 4-[(6-Methyl-2-pyrazinyl)oxy]benzoic acid (CAS: 906353-00-2)?

4-[(6-Methyl-2-pyrazinyl)oxy]benzoic acid is a chemical compound with the CAS nu...

906353-00-24-[(6-Methyl-2-pyraz...
Compound Q&A

What is 2-(2-Pyridinyl)-1,3-propanediol (CAS: 49745-42-8)?

2-(2-Pyridinyl)-1,3-propanediol (CAS: 49745-42-8) is a colorless to slightly yel...

49745-42-82-(2-Pyridinyl)-1,3-...
Compound Q&A

What is 2-(6-Chloro-2-pyridinyl)-2-phenylacetonitrile (CAS: 24783-42-4)?

2-(6-Chloro-2-pyridinyl)-2-phenylacetonitrile is an organic compound with the CA...

24783-42-42-(6-Chloro-2-pyridi...
Compound Q&A

What is 2-Oxopropanamide (CAS: 631-66-3)?

2-Oxopropanamide, also known as 2-aminoacrylic acid, is a chemical compound with...

631-66-32-Oxopropanamide
Compound Q&A

What is 2-Methyl-2-propanyl 4-(5-bromo-6-methyl-2-pyridinyl)-1-piperazinecarboxylate (CAS: 1289040-88-5)?

2-Methyl-2-propanyl 4-(5-bromo-6-methyl-2-pyridinyl)-1-piperazinecarboxylate (CA...

1289040-88-52-Methyl-2-propanyl ...
Compound Q&A

What is NAMPT inhibitor-linker 1 (CAS: 2241019-57-6)?

NAMPT inhibitor-linker 1 (CAS: 2241019-57-6) is a chemical compound designed as ...

2241019-57-6NAMPT inhibitor-link...
Compound Q&A

What is (2-(2,2,2-Trifluoroacetyl)pyridin-4-yl)boronic acid (CAS: 1310404-58-0)?

It is a chemical compound with the structure (2-(2,2,2-Trifluoroacetyl)pyridin-4...

1310404-58-0(2-(2,2,2-Trifluoroa...
Compound Q&A

What is 1-(2-Chlorophenyl)-6-(3,3,3-trifluoro-2-methylpropyl)-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one (CAS: 794568-90-4)?

1-(2-Chlorophenyl)-6-(3,3,3-trifluoro-2-methylpropyl)-1,5-dihydro-4H-pyrazolo[3,...

794568-90-41-(2-Chlorophenyl)-6...
Compound Q&A

What is Vinyl(chloromethyl)dimethoxysilane (CAS: 1314981-48-0)?

Vinyl(chloromethyl)dimethoxysilane is an organosilicon compound with the molecul...

1314981-48-0Vinyl(chloromethyl)d...

Supplier Information

Hangzhou Yaorieyicheng Biopharmaceutical Co., Ltd.

CAS Number: 290297-26-6

View Details
2-[3,5-Bis(trifluoromethyl)phenyl]-N,2-dimethyl-N-[4-(2-methylphenyl)-6-(4-methyl-1-piperazinyl)-3-pyridinyl]propanamide — Qingdao Kingways Biotechnology Co., Ltd.

Qingdao Kingways Biotechnology Co., Ltd.

CAS Number: 290297-26-6

View Details

Shanghai Jieshukai Biotechnology Co., Ltd.

CAS Number: 290297-26-6

View Details

SiChuanWeiKeJi Biotechnology Co Ltd

CAS Number: 290297-26-6

View Details

WuHanXinWeiYe Chemical Co Ltd

CAS Number: 290297-26-6

View Details
2-[3,5-Bis(trifluoromethyl)phenyl]-N,2-dimethyl-N-[4-(2-methylphenyl)-6-(4-methyl-1-piperazinyl)-3-pyridinyl]propanamide — ShangHaiMiXiu Chemical Co Ltd

ShangHaiMiXiu Chemical Co Ltd

CAS Number: 290297-26-6

View Details
2-[3,5-Bis(trifluoromethyl)phenyl]-N,2-dimethyl-N-[4-(2-methylphenyl)-6-(4-methyl-1-piperazinyl)-3-pyridinyl]propanamide — ShangHaiRuiFu Chemical Co Ltd

ShangHaiRuiFu Chemical Co Ltd

CAS Number: 290297-26-6

View Details

Chengdu Dalao Sanling Biotechnology Co., Ltd.

CAS Number: 290297-26-6

View Details
2-[3,5-Bis(trifluoromethyl)phenyl]-N,2-dimethyl-N-[4-(2-methylphenyl)-6-(4-methyl-1-piperazinyl)-3-pyridinyl]propanamide — ShenZhenZhenJiangShengWuJiShu Co Ltd

ShenZhenZhenJiangShengWuJiShu Co Ltd

CAS Number: 290297-26-6

View Details
2-[3,5-Bis(trifluoromethyl)phenyl]-N,2-dimethyl-N-[4-(2-methylphenyl)-6-(4-methyl-1-piperazinyl)-3-pyridinyl]propanamide — Shanghai SameSharp Biotechnology Co., Ltd.

Shanghai SameSharp Biotechnology Co., Ltd.

CAS Number: 290297-26-6

View Details

ShangHaiMaiKeLinShengHuaKeJi Inc

CAS Number: 290297-26-6

View Details

JiangSuBeiDaYiYao Technology Co Ltd

CAS Number: 290297-26-6

View Details
2-[3,5-Bis(trifluoromethyl)phenyl]-N,2-dimethyl-N-[4-(2-methylphenyl)-6-(4-methyl-1-piperazinyl)-3-pyridinyl]propanamide — Jin Jinle (Hunan) Chemical Co., Ltd.

Jin Jinle (Hunan) Chemical Co., Ltd.

CAS Number: 290297-26-6

View Details
2-[3,5-Bis(trifluoromethyl)phenyl]-N,2-dimethyl-N-[4-(2-methylphenyl)-6-(4-methyl-1-piperazinyl)-3-pyridinyl]propanamide — Shanghai Yuyeh Biotechnology Co., Ltd.

Shanghai Yuyeh Biotechnology Co., Ltd.

CAS Number: 290297-26-6

View Details

Shanghai Yuansi Biotechnology Co., Ltd.

CAS Number: 290297-26-6

View Details

This website uses cookies to ensure basic functionality and enhance your experience. We use:

  • Essential cookies: Required for core site features (authentication, security). These cannot be disabled.
  • Analytics cookies: Help us understand site usage to improve our service.

You can change your preferences at any time in our Privacy Settings. See our Privacy Policy for more details.