N-[(9H-Fluoren-9-ylmethoxy)carbonyl]glycine

Basic Information

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CAS Number

29022-11-5

Molecular Formula

C17H15NO4

Molecular Weight

297.31 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Basic Physical Properties

Melting Point

175.0 to 178.0 deg-C

Boiling Point

545.7°C at 760 mmHg

Flash Point

283.8 °C

Refractive Index

1.4500 (estimate)

SMILES

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C1=CC=C2C(=C1)C(C3=CC=CC=C32)COC(=O)NCC(=O)O

InChI

InChI=1S/C17H15NO4/c19-16(20)9-18-17(21)22-10-15-13-7-3-1-5-11(13)12-6-2-4-8-14(12)15/h1-8,15H,9-10H2,(H,18,21)(H,19,20)

InChIKey

NDKDFTQNXLHCGO-UHFFFAOYSA-N

LogP

2.6097

Topological Polar Surface Area

75.63000000000001 Å²

Hydrogen Bond Donor/Acceptor

2 / 5

Complexity

403

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

AM81783
J-300134
Fmoc-Gly-OH
A819722
Glycine, N-((9H-fluoren-9-ylmethoxy)carbonyl)-
AB01621
NSC 334288
N-(9-fluorenylmethyoxycarbonyl)-glycine
Fmoc-glycine
N-Fmoc-glycine
Glycine-15N, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-
N-Fmocglycine
2-((((9H-FLUOREN-9-YL)METHOXY)CARBONYL)AMINO)ACETIC ACID
FMOC-GLY
DTXSID60183262
GLYCINE-2,2-D2-N-FMOC
AS-12722
N-ALPHA-(9-FLUORENYLMETHYLOXYCARBONYL)-GLYCINE
Z104483012
EN300-20812
HY-Y1250
9-FLUORENYLMETHOXYCARBONYL-GLYCINE
NPC-14692
Maybridge3_001527
NSC334288
N-Fluorenylmethoxycarbonylglycine
[[[(9H-Fluoren-9-yl)methoxy]carbonyl]amino]acetic acid
Oprea1_648851
2-({[(9H-FLUOREN-9-YL)METHOXY]CARBONYL}AMINO)ACETIC ACID
NDKDFTQNXLHCGO-UHFFFAOYSA-N
AC-8593

MDL Number

MFCD00037140

Customs Code

29242995

FAQ

What is N-[(9H-Fluoren-9-ylmethoxy)carbonyl]glycine (CAS: 29022-11-5)?

N-[(9H-Fluoren-9-ylmethoxy)carbonyl]glycine (CAS: 29022-11-5) is a protected amino acid derivative commonly used in peptide synthesis. Its chemical formula is C19H17NO4, and it exhibits typical characteristics of a solid with moderate solubility in polar solvents. The compound features a fluorenylmethoxy carbonyl (Fmoc) group attached to glycine, making it a key intermediate in organic chemistry and pharmaceutical research.

What are the main uses of N-[(9H-Fluoren-9-ylmethoxy)carbonyl]glycine (CAS: 29022-11-5)?

N-[(9H-Fluoren-9-ylmethoxy)carbonyl]glycine (CAS: 29022-11-5) is primarily used in pharmaceuticals for drug development and as a building block in peptide synthesis. It also finds applications in organic chemistry research, functional group modification, and industrial processes requiring stable, reactive intermediates. Its role in protecting amino groups makes it valuable in synthesizing complex molecules.

Is N-[(9H-Fluoren-9-ylmethoxy)carbonyl]glycine (CAS: 29022-11-5) safe?

N-[(9H-Fluoren-9-ylmethoxy)carbonyl]glycine (CAS: 29022-11-5) is generally considered safe with proper handling. It has low acute toxicity but requires precautions such as avoiding inhalation, skin contact, and ingestion. Safety standards recommend using appropriate PPE, working in a well-ventilated area, and adhering to OSHA guidelines to ensure safe laboratory practices.

How should N-[(9H-Fluoren-9-ylmethoxy)carbonyl]glycine (CAS: 29022-11-5) be stored?

N-[(9H-Fluoren-9-ylmethoxy)carbonyl]glycine (CAS: 29022-11-5) should be stored in a cool, dry, and dark environment to maintain stability. Keep in airtight containers away from moisture and light, and ensure it is stored under an inert atmosphere (e.g., nitrogen) if necessary. Avoid exposure to incompatible substances and maintain storage conditions as per safety data sheets for long-term preservation.