Boc-Phg-OH | CAS No. 2900-27-8

Boc-Phg-OH

Basic Information

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CAS Number

2900-27-8

Molecular Formula

C13H17NO4

Molecular Weight

251.28 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Basic Physical Properties

Melting Point

91.0 to 95.0 deg-C

Boiling Point

407.2℃ at 760 mmHg

Flash Point

200.1°C

Refractive Index

1.532

Specific Rotation

144 ±2° (c=1%, in ethanol)

SMILES

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CC(C)(C)OC(=O)NC(C1=CC=CC=C1)C(=O)O

InChI

InChI=1S/C13H17NO4/c1-13(2,3)18-12(17)14-10(11(15)16)9-7-5-4-6-8-9/h4-8,10H,1-3H3,(H,14,17)(H,15,16)/t10-/m0/s1

InChIKey

HOBFSNNENNQQIU-JTQLQIEISA-N

LogP

2.3370000000000006

Topological Polar Surface Area

75.63 Å²

Hydrogen Bond Donor/Acceptor

2 / 5

Complexity

303

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

(s)-2-[(t-butoxycarbonyl)amino]-2-phenylacetic acid
Boc-L-Phg-OH
(S)-2-(tert-butoxycarbonylamino)-2-phenylacetic acid
Boc-Phg-OH
Boc-L-alpha-phenylglycine
SCHEMBL264362
AKOS015924161
(2S)-2-{[(tert-butoxy)carbonyl]amino}-2-phenylacetic acid
AS-12739
(S)-BOC-L-PHENYLGLYCINE
HY-W011913
N-Boc-L-phenyl glycine
J-017350
HOBFSNNENNQQIU-JTQLQIEISA-N
(2S)-2-[(2-methylpropan-2-yl)oxycarbonylamino]-2-phenylacetic acid
B3211
(2s)-[(tert-butoxycarbonyl)amino](phenyl)ethanoic acid
M03228
2900-27-8
N-BOC-L-ALPHA-PHENYLGLYCINE
MFCD00065588
(S)-2-((tert-Butoxycarbonyl)amino)-2-phenylacetic acid
Boc-L-Phenylglycine
CS-W012629
Boc-L-a-phenylglycine
(S)-N-tert-butoxycarbonyl-2-phenylglycine
EN300-30946
Z317062680
N-(tert-Butoxycarbonyl)-L-2-phenylglycine
DTXSID30451804
Boc-Phg-OH, >=99.0% (T)

MDL Number

MFCD00065588

Customs Code

2924299090

FAQ

What is Boc-Phg-OH (CAS: 2900-27-8)?

Boc-Phg-OH (CAS: 2900-27-8) is an amino acid derivative used in peptide synthesis as a protecting group. It is also known as 1-[(benzyloxycarbonyl)amino]guanidino-4-hydroxybenzylamine. This compound is widely used in organic chemistry and pharmaceutical research for its ability to modify amino acids during synthetic processes.

What are the main uses of Boc-Phg-OH (CAS: 2900-27-8)?

Boc-Phg-OH (CAS: 2900-27-8) is primarily used in the synthesis of peptides and proteins. It serves as a protecting group, stabilizing the guanidino function during solid-phase peptide synthesis. This compound is crucial in the development of pharmaceuticals and biotherapeutics, enhancing the efficiency of chemical reactions and protecting functional groups during synthesis.

Is Boc-Phg-OH (CAS: 2900-27-8) safe?

Boc-Phg-OH (CAS: 2900-27-8) can be handled safely with appropriate precautions. It is important to use personal protective equipment (PPE) such as gloves and safety goggles. Exposure to this compound should be minimized, and it should be stored in a cool, dry place away from direct sunlight. Ensure proper ventilation when handling to avoid inhalation and ingestion risks.

How should Boc-Phg-OH (CAS: 2900-27-8) be stored?

Boc-Phg-OH (CAS: 2900-27-8) should be stored in a cool, dry environment away from direct sunlight and heat sources. It is best kept in a tightly sealed container to prevent moisture absorption. Store at room temperature or in a refrigerator, but avoid freezing to maintain its stability. It is important to keep it away from incompatible materials and ensure good ventilation in the storage area to prevent any potential chemical reactions.