1,3-Thiazole | CAS No. 288-47-1

1,3-Thiazole

Basic Information

View in Editor

CAS Number

288-47-1

Molecular Formula

C3H3NS

Molecular Weight

85.13 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

Melting Point

-33°C

Boiling Point

117-118 °C

Refractive Index

n20/D 1.538(lit.)

SMILES

View in Editor

S1C=NC=C1

InChI

InChI=1S/C3H3NS/c1-2-5-3-4-1/h1-3H

InChIKey

FZWLAAWBMGSTSO-UHFFFAOYSA-N

LogP

1.1431

pKa

2.44(at 20℃)

Topological Polar Surface Area

12.89 Å²

Hydrogen Bond Donor/Acceptor

0 / 1

Complexity

30.1

Safety Information

View Safety Information

GHS Hazard Pictograms

H226

H302

H315

H318

H335

Hazard Statement

H226 Flammable liquid and vapor
Flammable liquids

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H318 Causes serious eye damage
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Hazard Class

Class 3 Class 3

Stability

Stable. Incompatible with strong oxidizing agents.

Sensitiveness

Air & Light Sensitive

Synonyms & References

English

Thiazole
1,3-THIAZOLE
FEMA 3615
FEMA NUMBER 3615
THIAN-4-ONEOXIME
MA300208
3-Azathiophene

MDL Number

MFCD00005315

Customs Code

2934100090

FAQ

What is 1,3-Thiazole (CAS: 288-47-1)?

1,3-Thiazole is a heterocyclic organic compound with the chemical formula C3H3NS. It consists of a five-membered ring containing three carbon atoms, one nitrogen atom, and one sulfur atom. This compound is known for its aromatic properties and is commonly used as a building block in the synthesis of various pharmaceuticals and agrochemicals. It appears as a pale yellow solid and has a characteristic odor.

What are the main uses of 1,3-Thiazole (CAS: 288-47-1)?

1,3-Thiazole is widely used in the pharmaceutical industry for the production of drugs such as antibiotics, antifungal agents, and analgesics. It also finds applications in the synthesis of dyes, pesticides, and other industrial chemicals. In research, it serves as a key intermediate in the development of new materials and organic compounds. Its versatility makes it an important compound in both medicinal and chemical applications.

Is 1,3-Thiazole (CAS: 288-47-1) safe?

1,3-Thiazole is generally considered safe when handled properly, but it may cause irritation to the skin, eyes, and respiratory system. Safety data sheets recommend using appropriate personal protective equipment (PPE) such as gloves and goggles. It is classified as a hazardous substance under certain regulations, so proper storage and handling are essential to ensure safety in both industrial and laboratory settings.

How should 1,3-Thiazole (CAS: 288-47-1) be stored?

1,3-Thiazole should be stored in a cool, dry, and well-ventilated place, away from moisture and light. It is typically kept in a sealed container made of glass or high-density polyethylene (HDPE) to maintain stability. Storage conditions should be below 25°C and with humidity levels below 60% to prevent degradation. Always store away from incompatible materials to ensure safety.