N-Cbz-2-piperidinecarboxylic acid

Basic Information

View in Editor

CAS Number

28697-07-6

Molecular Formula

C14H17NO4

Molecular Weight

263.29 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Basic Physical Properties

Physical State

Solid

Melting Point

78.0 to 82.0 deg-C

Boiling Point

443.9°C at 760 mmHg

Density

1.265

Flash Point

222.3°C

SMILES

View in Editor

C1CCN(C(C1)C(=O)O)C(=O)OCC2=CC=CC=C2

InChI

InChI=1S/C14H17NO4/c16-13(17)12-8-4-5-9-15(12)14(18)19-10-11-6-2-1-3-7-11/h1-3,6-7,12H,4-5,8-10H2,(H,16,17)

InChIKey

ZSAIHAKADPJIGN-UHFFFAOYSA-N

LogP

2.2622999999999998

Topological Polar Surface Area

66.84 Å²

Hydrogen Bond Donor/Acceptor

1 / 5

Complexity

325

Safety Information

View Safety Information

Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

Synonyms & References

English

AM20060867
FT-0638796
AB10418
AS-11197
N-Cbz-2-pperdnecarboxylc acd
N-Cbz-2-Piperidinecarboxylic acid
1-Cbz-Piperidine-2-Carboxylic Acid
AKOS000169552
1-((benzyloxy)carbonyl)piperidine-2-carboxylic acid
ZSAIHAKADPJIGN-UHFFFAOYSA-N
N-CBZ-piperidine-2-carboxylic acid
AB10397
1-phenylmethoxycarbonylpiperidine-2-carboxylic Acid
1-[(benzyloxy)carbonyl]piperidine-2-carboxylic acid
1-CBZ-2-PIPERIDINECARBOXYLIC ACID
N-CBZ-piperidine-2-carboxylicacid
SY020431
SB36389
1-N-Cbz-piperidine-2-carboxylic acid
n-benzyloxycarbonylpiperidine-2-carboxylic acid
ZSAIHAKADPJIGN-UHFFFAOYSA-
28697-07-6
AKOS016842268
FT-0638797
A837103
N-Carbobenzyloxypiperidine-2-carboxylic acid
C3382
MFCD01863645
A5418
J-523532
N-Carbobenzyloxy-2-piperidinecarboxylic acid

MDL Number

MFCD01863568

Customs Code

2933399090

FAQ

What regulatory guidelines apply to N-Cbz-2-piperidinecarboxylic acid (CAS: 28697-07-6)?

N-Cbz-2-piperidinecarboxylic acid (CAS: 28697-07-6) falls under the scope of the REACH regulation in the EU, which requires manufacturers and importers to register substances above a certain tonnage. In the US, it is regulated by the EPA under the Toxic Substances Control Act (TSCA). The compound may also require GHS classification and labeling based on its physical and chemical properties. FDA oversight is primarily concerned with its use in pharmaceutical applications, where it must comply with pharmaceutical regulations.

Are there alternatives to N-Cbz-2-piperidinecarboxylic acid (CAS: 28697-07-6) in synthesis?

Several alternatives to N-Cbz-2-piperidinecarboxylic acid (CAS: 28697-07-6) can be used in synthesis, including other piperidine carboxylic acids or their derivatives. Common substitutes include N-Cbz-5-hydroxy-2-piperidinecarboxylic acid and N-Cbz-2-pyrrolidinecarboxylic acid. These alternatives offer similar functionalities but may have different reactivity and solubility profiles.

What is the market or research trend for N-Cbz-2-piperidinecarboxylic acid (CAS: 28697-07-6)?

N-Cbz-2-piperidinecarboxylic acid (CAS: 28697-07-6) is increasingly being used in the synthesis of peptides and other organic molecules. Research trends indicate a growing interest in its use as a solid-phase peptide synthesis reagent. Market demand is driven by advancements in pharmaceutical research and drug discovery. However, price fluctuations may impact market trends, with economic factors and supply chain issues influencing availability and cost.

How should waste containing N-Cbz-2-piperidinecarboxylic acid (CAS: 28697-07-6) be handled?

Waste containing N-Cbz-2-piperidinecarboxylic acid (CAS: 28697-07-6) should be collected in appropriate containers and stored under proper environmental conditions to prevent contamination. Incineration or professional waste disposal services are recommended for safe disposal. Employers should follow local regulations and adhere to best practices in waste management to ensure compliance with environmental protection standards and minimize ecological impact.