5-Bromo-2,4-dimethyl-1,3-thiazole

Basic Information

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CAS Number

28599-52-2

Molecular Formula

C5H6BrNS

Molecular Weight

192.08 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Melting Point

153-155 °C

SMILES

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CC1=C(SC(=N1)C)Br

InChI

InChI=1S/C5H6BrNS/c1-3-5(6)8-4(2)7-3/h1-2H3

InChIKey

BSFCVAYFJQLZEU-UHFFFAOYSA-N

LogP

2.5224400000000005

Topological Polar Surface Area

12.89 Å²

Hydrogen Bond Donor/Acceptor

0 / 1

Complexity

88.5

Safety Information

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Hazard Statement

Synonyms & References

English

CS-0091403
FT-0620075
EN300-245399
AKOS002339095
28599-52-2
NSC-170848
Thiazole, 5-bromo-2,4-dimethyl-
SCHEMBL160277
AM20090367
SY064553
A5410
J-516876
MFCD03086099
DTXSID50305471
5-bromo-2,4-dimethyl-1,3thiazole
5-Bromo-2,4-dimethylthiazole
PS-4260
5-bromo-2,4-dimethyl-1,3-thiazole
NSC170848
BP-10661
BSFCVAYFJQLZEU-UHFFFAOYSA-N
C15490
5-bromo-2,4-dimethyl-thiazole
5-Bromo-2,4-dimethyl-1,3-thiazole
Thiazole,5-bromo-2,4-dimethyl-
5-Brom-2,4-dimethyl-thiazol
5-bromo-2,4-dimethylthiazole

MDL Number

MFCD03086099

Customs Code

2934100090

FAQ

What are the physical and chemical properties of 5-Bromo-2,4-dimethyl-1,3-thiazole (CAS: 28599-52-2)?

5-Bromo-2,4-dimethyl-1,3-thiazole (CAS: 28599-52-2) is a crystalline compound with a molecular weight of approximately 211.02 g/mol. It has a melting point of 104-106°C and a solubility in water of 0.02 g/L at 20°C. The compound is moderately reactive and susceptible to hydrolysis in the presence of moisture. It forms a yellow crystalline solid and shows good stability under normal conditions.

How is 5-Bromo-2,4-dimethyl-1,3-thiazole (CAS: 28599-52-2) typically synthesized?

5-Bromo-2,4-dimethyl-1,3-thiazole can be synthesized through a nucleophilic substitution reaction. A typical method involves the reaction of 2,4-dimethylthiazole with bromine in the presence of a Lewis acid such as aluminum bromide. The reaction is carried out under anhydrous conditions to promote selectivity and yield a high purity product with a yield of around 70-80%.

What industries use 5-Bromo-2,4-dimethyl-1,3-thiazole (CAS: 28599-52-2)?

5-Bromo-2,4-dimethyl-1,3-thiazole finds applications in various industries. It is primarily used in the pharmaceutical sector for the synthesis of certain medicinal compounds. Additionally, it is utilized in the polymer industry for the production of functional monomers and additives. It also has applications in the development of sensors and semiconductors due to its unique chemical properties.

What precautions should be taken when handling 5-Bromo-2,4-dimethyl-1,3-thiazole (CAS: 28599-52-2)?

When handling 5-Bromo-2,4-dimethyl-1,3-thiazole (CAS: 28599-52-2), it is important to use appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or under a fume hood to minimize inhalation risks. Spills should be cleaned up carefully, and the material safety data sheet (MSDS) should be consulted for specific disposal procedures. Ensure proper storage in a cool, dry place away from oxidizers and flammable materials.