2-Methoxy-3-methylpyrazine

Basic Information

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CAS Number

2847-30-5

Molecular Formula

C6H8N2O

Molecular Weight

124.14 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

Boiling Point

87°C/60mmHg

Refractive Index

n20/D 1.507(lit.)

SMILES

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COc1nccnc1C

InChI

InChI=1S/C6H8N2O/c1-5-6(9-2)8-4-3-7-5/h3-4H,1-2H3

InChIKey

VKJIAEQRKBQLLA-UHFFFAOYSA-N

LogP

0.7936199999999999

Topological Polar Surface Area

35.010000000000005 Å²

Hydrogen Bond Donor/Acceptor

0 / 3

Complexity

87.1

Safety Information

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GHS Hazard Pictograms

H226

H302

H315

H318

H335

Hazard Statement

H226 Flammable liquid and vapor
Flammable liquids

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H318 Causes serious eye damage
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Hazard Class

Class 3 Class 3

Synonyms & References

English

2-Methoxy-3-methylpyrazine
2-Methyl-3-methoxypyrazine
2-Methoxy-3(5or6)-methylpyrazine
2-Methoxy-3-Methylpy
2-Methoxy-3-methylpyrazin
2-methoxy-3-methyl-pyrazine
2-Methoxy-3-methylpyrazine1000µg
2-METHYL-6-METHOXYPYRAZINE
3-Methoxy-2-methyl-pyrazin
3-Methyl-2-methoxypyrazine
FEMA 3183
FEMA NUMBER 3183
METHOXYMETHYLPYRAZINE
METHYL METHOXY PYRAZINE
2-Methoxy-3-methyl pyrazine
2-methoxy-3-methylpyrazine

MDL Number

MFCD00006127

Customs Code

2933990090

FAQ

What are the physical and chemical properties of 2-Methoxy-3-methylpyrazine (CAS: 2847-30-5)?

2-Methoxy-3-methylpyrazine (CAS: 2847-30-5) is a colorless liquid with a characteristic aroma. It has a molecular weight of approximately 132.14 g/mol and a density of 1.04 g/cm³. This compound is soluble in ethanol and other organic solvents but insoluble in water. It is relatively stable under normal conditions but can react with strong oxidizers. It is commonly used in the flavor and fragrance industry due to its pleasant aroma.

How is 2-Methoxy-3-methylpyrazine (CAS: 2847-30-5) typically synthesized?

2-Methoxy-3-methylpyrazine (CAS: 2847-30-5) can be synthesized from methylpyrazine using methanol in the presence of a strong acid catalyst, such as hydrochloric acid. The reaction is exothermic and generates the desired product with good yield. Other methods include the reduction of 3-methylpyrazine-2-carbaldehyde using hydrogen in the presence of a palladium catalyst, followed by methylation with methyl iodide.

What industries use 2-Methoxy-3-methylpyrazine (CAS: 2847-30-5)?

2-Methoxy-3-methylpyrazine (CAS: 2847-30-5) is widely used in the flavor and fragrance industry, where it imparts a unique aroma to food and beverages. It is also utilized in the tobacco industry to enhance the flavor of tobacco products. Additionally, it has applications in the perfume and cosmetic industries. Due to its chemical stability, it is also used in the pharmaceutical and polymer industries as a stabilizer and antioxidant.

What precautions should be taken when handling 2-Methoxy-3-methylpyrazine (CAS: 2847-30-5)?

When handling 2-Methoxy-3-methylpyrazine (CAS: 2847-30-5), it is essential to wear appropriate personal protective equipment (PPE) such as safety glasses, gloves, and a lab coat to protect against skin and eye contact. It should be stored in a cool, dry place away from strong oxidizers and other incompatible chemicals. Fume hoods should be used during handling to minimize inhalation. In case of a spill, neutralize the area with water and clean up according to standard safety protocols. Always refer to the Material Safety Data Sheet (MSDS) for detailed safety information.