2-Chloro-6-[(2R)-2-hydroxy-3-{[2-methyl-1-(2-naphthyl)-2-propanyl]amino}propoxy]benzonitrile

Basic Information

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CAS Number

284035-33-2

Molecular Formula

C24H25ClN2O2

Molecular Weight

17.03 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Nitriles

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Boiling Point

608.4°C at 760 mmHg

Density

1.23

Flash Point

608.4 °C at 760 mmHg

Refractive Index

1.631

SMILES

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CC(C)(CC1=CC2=CC=CC=C2C=C1)NCC(COC3=C(C(=CC=C3)Cl)C#N)O

InChI

InChI=1S/C24H25ClN2O2/c1-24(2,13-17-10-11-18-6-3-4-7-19(18)12-17)27-15-20(28)16-29-23-9-5-8-22(25)21(23)14-26/h3-12,20,27-28H,13,15-16H2,1-2H3/t20-/m1/s1

InChIKey

PZUJQWHTIRWCID-HXUWFJFHSA-N

LogP

0.16199999999999998

Topological Polar Surface Area

35.0 Å²

Hydrogen Bond Donor/Acceptor

3 / 1

Complexity

560

Safety Information

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Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

BDBM50161093
(+)-NPS-2143
NPS-2143(SB 262470A )
UNII-Z25PJ77W7V
(R)-2-chloro-6-(2-hydroxy-3-((2-methyl-1-(naphthalen-2-yl)propan-2-yl)amino)propoxy)benzonitrile
BCPP000077
NPS-2143 (SB262470)
2-chloro-6-[(2R)-2-hydroxy-3-[(2-methyl-1-naphthalen-2-ylpropan-2-yl)amino]propoxy]benzonitrile
CHEMBL180672
2-chloro-6-[(2R)-2-hydroxy-3-{[2-methyl-1-(naphthalen-2-yl)propan-2-yl]amino}propoxy]benzonitrile
SW219455-1
2-Chloro-6-[((2R)-3-([1,1-dimethyl-2-(2-naphthalenyl)ethyl]-amino)-2-hydroxypropyl)oxy]benzonitrile hydrochloride
Benzonitrile, 2-chloro-6-((2R)-3-((1,1-dimethyl-2-(2-naphthalenyl)ethyl)amino)-2-hydroxypropoxy)-
NS00069698
DTXSID10426075
SB-262470A
DB05695
HY-10007
SB 262470A
NPS 2143
AKOS025401886
2-Chloro-6-[(R)-3-(1,1-dimethyl-2-naphthalen-2-yl-ethylamino)-2-hydroxy-propoxy]-benzonitrile
BCP02421
2-Chloro-6-((2R)-3-((1,1-dimethyl-2-(2-naphthalenyl)ethyl)amino)-2-hydroxypropoxy)benzonitrile
MFCD04113010
Z25PJ77W7V
SB-262470
Q20707377
EX-A017
SB262470
GTPL716

MDL Number

MFCD04113010

FAQ

What regulatory guidelines apply to 2-Chloro-6-[(2R)-2-hydroxy-3-{[2-methyl-1-(2-naphthyl)-2-propanyl]amino}propoxy]benzonitrile (CAS: 284035-33-2)?

This compound falls under the scope of the Globally Harmonized System of Classification and Labelling of Chemicals (GHS), REACH regulations in the European Union, and FDA/EPA requirements in the USA. It is classified as a hazardous substance based on its properties and must comply with specific handling, storage, and disposal guidelines to ensure safety and environmental protection.

Are there alternatives to 2-Chloro-6-[(2R)-2-hydroxy-3-{[2-methyl-1-(2-naphthyl)-2-propanyl]amino}propoxy]benzonitrile (CAS: 284035-33-2) in synthesis?

Alternatives to this compound include similar naphthyl-containing derivatives with different functional groups or simpler structural analogs. Commonly used reagents in synthesis include chloroacetic acid derivatives, naphthylamines, and various amino acids. These alternatives can serve as effective substitutes depending on the specific application and requirements of the synthesis process.

What is the market or research trend for 2-Chloro-6-[(2R)-2-hydroxy-3-{[2-methyl-1-(2-naphthyl)-2-propanyl]amino}propoxy]benzonitrile (CAS: 284035-33-2)?

The market for this compound is currently stable, with a focus on its application in pharmaceuticals and fine chemicals. Research trends include the development of more efficient synthesis methods and the exploration of its potential in novel drug candidates. Price trends indicate a relatively consistent demand, with occasional fluctuations due to supply chain issues or changes in regulatory requirements.

How should waste containing 2-Chloro-6-[(2R)-2-hydroxy-3-{[2-methyl-1-(2-naphthyl)-2-propanyl]amino}propoxy]benzonitrile (CAS: 284035-33-2) be handled?

Waste containing this compound should be collected in appropriate containers lined with impermeable materials to prevent leakage. It should then be treated through incineration or professional waste disposal services. Environmental protection precautions include ensuring proper ventilation during handling and disposing of any contaminated materials in accordance with local waste management regulations to minimize environmental impact.