4-Amino-2-methylphenol

Basic Information

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CAS Number

2835-96-3

Molecular Formula

C7H9NO

Molecular Weight

123.15 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Physical Properties

Melting Point

174-176 ºC

Boiling Point

278.8℃ at 760 mmHg

Refractive Index

1.5706 (estimate)

SMILES

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CC1=C(C=CC(=C1)N)O

InChI

InChI=1S/C7H9NO/c1-5-4-6(8)2-3-7(5)9/h2-4,9H,8H2,1H3

InChIKey

HDGMAACKJSBLMW-UHFFFAOYSA-N

LogP

1.2828199999999998

Topological Polar Surface Area

46.25 Å²

Hydrogen Bond Donor/Acceptor

3 / 2

Complexity

94.9

Safety Information

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Hazard Statement

H303 May be harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

Synonyms & References

English

W-107050
Q27275742
2-Methyl-4-aminophenol
Phenol, 4-amino-2-methyl-
AM84881
NS00028474
2835-96-3
4-Amino-o-cresol
FT-0634418
FT-0659627
4llp
CS8D10SY5L
2635-95-2
3-Methyl-4-hydroxyaniline
o-Cresol, 4-amino-
2-methyl-p-aminophenol
5-amino-o-kresol
DTXSID2062662
4-Amino-2 methylphenol
SY021230
EINECS 220-619-1
4-azanyl-2-methyl-phenol
A818404
4ZE
4A2MP
4-Amino-2-methylphenol
3-Amino-6-hydroxytoluene
EN300-112638
AC-7841
SCHEMBL33808
4-amino-ortho-cresol

MDL Number

MFCD00007878

Customs Code

2922299090

FAQ

What are the physical and chemical properties of 4-Amino-2-methylphenol (CAS: 2835-96-3)?

4-Amino-2-methylphenol (CAS: 2835-96-3) is a white to off-white crystalline solid with a molecular weight of approximately 151.19 g/mol. It is slightly soluble in water and more soluble in organic solvents. The compound exhibits basic properties due to the amino group and shows reactivity towards acid-base reactions and electrophilic aromatic substitution.

How is 4-Amino-2-methylphenol (CAS: 2835-96-3) typically synthesized?

4-Amino-2-methylphenol (CAS: 2835-96-3) is commonly synthesized by the reduction of 2-methylbenzaldehyde with sodium borohydride, followed by the addition of amines. Alternatively, it can be produced via the hydrogenation of 2-methylbenzoyl chloride, yielding the corresponding phenol which is then aminated.

What industries use 4-Amino-2-methylphenol (CAS: 2835-96-3)?

4-Amino-2-methylphenol (CAS: 2835-96-3) is primarily used in the pharmaceutical industry for the synthesis of various drugs, particularly those requiring basic functional groups. It also finds applications in the production of dyes, polymers, and as a component in some sensor technologies.

What precautions should be taken when handling 4-Amino-2-methylphenol (CAS: 2835-96-3)?

When handling 4-Amino-2-methylphenol (CAS: 2835-96-3), it is essential to wear appropriate personal protective equipment (PPE) such as gloves, safety glasses, and a lab coat. This compound should be used in a well-ventilated area or a fume hood to avoid inhalation. Spills should be handled with care, and the material safety data sheet (MSDS) should be consulted for detailed spill procedures.