5(6)-Aminofluorescein

Basic Information

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CAS Number

27599-63-9

Molecular Formula

C40H26N2O10

Molecular Weight

347.33 g/mol

EINECS

222-043-6

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Esters

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Basic Physical Properties

Melting Point

223 °C (dec.)

Boiling Point

695.3ºC at 760 mmHg

Density

1.64

Flash Point

695.3 °C at 760 mmHg

SMILES

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O=C1OC2(C3=C(OC4=C2C=CC(O)=C4)C=C(O)C=C3)C5=C1C=C(N)C=C5

InChI

InChI=1S/C20H13NO5/c21-10-1-4-14-13(7-10)19(24)26-20(14)15-5-2-11(22)8-17(15)25-18-9-12(23)3-6-16(18)20/h1-9,22-23H,21H2

InChIKey

GZAJOEGTZDUSKS-UHFFFAOYSA-N

LogP

3.248000000000001

Topological Polar Surface Area

102.01 Å²

Hydrogen Bond Donor/Acceptor

4 / 6

Complexity

557

Safety Information

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Stability

对光和湿气敏感

Synonyms & References

English

FLUORESCEINAMINE
FLUORESCEINAMINE, ISOMER 1
FLUORESCEINAMINE ISOMER I
4-AMINOFLUORESCEIN ISOMER I
4-AMINOFLUORESCEIN
5-AMINO-3',6'-DIHYDROXYSPIRO[ISOBENZOFURAN-1(3H),9'-(9H)XANTHEN]-3-ONE
5-AMINOFLUORESCEIN ISOMER I
5(6)-Aminofluorescein
5-Aminofluorescein
Fluoresceinamine
FLUORESCEINAMINE, MIXTUREOFISOMERS,(AMINOFLUORESCEIN)
1-AMINOFLUORESCEIN
1-FLUORESCEINAMINE
5(6)-AFM
AMINOFLUORESCEIN
Fluoresceinamine mixed isomers
FLUORESCEINAMINE,ISOMER 1
Fluorescein,5(or 6)-amino- (8CI)
Fluorescein, amino- (6CI,7CI)
Fluorescein amine
Fluoresceinamine, isomer I
Spiro[isobenzofuran-1(3H),9'-[9H]xanthen]-3-one, 5-amino-3',6'-dihydroxy-
5(6)-Aminofluorescein (Mixture of isomers)
Fluoresceinamine isomer I, pure
5-amino-3',6'-dihydroxy-3H-spiro[2-benzofuran-1,9'-xanthen]-3-one
5-AMINO-3',6'-DIHYDROXY-3H-SPIRO[2-BENZOFURAN-1,9'-XANTHENE]-3-ONE
Fluoresceinamine-I
Spiro(isobenzofuran-1(3

MDL Number

MFCD00133331

EC Number

222-043-6

Customs Code

29321900

FAQ

What regulatory guidelines apply to 5(6)-Aminofluorescein (CAS: 27599-63-9)?

5(6)-Aminofluorescein (CAS: 27599-63-9) is classified as a skin and eye irritant under the Globally Harmonized System of Classification and Labeling of Chemicals (GHS). It is regulated under the REACH regulations in the EU, which require manufacturers and importers to register substances, assess their safety, and manage the risks associated with their use. In the USA, the Environmental Protection Agency (EPA) and the Food and Drug Administration (FDA) have specific guidelines for handling and disposing of this compound to ensure environmental safety and compliance with health standards.

Are there alternatives to 5(6)-Aminofluorescein (CAS: 27599-63-9) in synthesis?

Several alternatives to 5(6)-Aminofluorescein (CAS: 27599-63-9) are available in synthesis, including 6-Aminofluorescein and 5-Aminofluorescein. These compounds can be used as fluorescent probes in similar applications. Other substitutes like 5(6)-Carboxyfluorescein (FAM) or 6-Carboxyfluorescein (TAMRA) are also common in fluorescence labeling and detection due to their similar properties and reactivity.

What is the market or research trend for 5(6)-Aminofluorescein (CAS: 27599-63-9)?

The market for 5(6)-Aminofluorescein (CAS: 27599-63-9) is driven by its extensive use in fluorescence labeling, bioimaging, and molecular diagnostics. Research trends focus on developing more efficient and environmentally friendly synthesis methods, as well as exploring its applications in novel fluorescent tagging techniques. Increasing awareness of the compound's safety and regulatory compliance is also influencing market dynamics, leading to a growing demand for its use in industrial and academic settings.

How should waste containing 5(6)-Aminofluorescein (CAS: 27599-63-9) be handled?

Waste containing 5(6)-Aminofluorescein (CAS: 27599-63-9) should be collected in suitable, leak-proof containers and stored in a cool, well-ventilated area away from direct sunlight. Proper incineration is recommended for disposal, ensuring that emissions are within safe limits as per EPA regulations. Alternatively, professional waste disposal services can be utilized to ensure compliance with local and international environmental standards. It is crucial to follow local disposal laws and guidelines to minimize environmental impact.