Trimethylsilyl acetate

Basic Information

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CAS Number

2754-27-0

Molecular Formula

C5H12O2Si

Molecular Weight

132.23 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Water Treatment Chemicals Coagulants and Flocculants Inorganic Coagulants

Basic Physical Properties

Melting Point

−32 °C

Boiling Point

107.5 °C

Refractive Index

n20/D 1.388(lit.)

Vapor Pressure

35 mmHg ( 30 °C)

SMILES

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CC(=O)O[Si](C)(C)C

InChI

InChI=1S/C5H12O2Si/c1-5(6)7-8(2,3)4/h1-4H3

InChIKey

QHUNJMXHQHHWQP-UHFFFAOYSA-N

LogP

1.3844

Topological Polar Surface Area

26.3 Å²

Hydrogen Bond Donor/Acceptor

0 / 2

Complexity

93.1

Safety Information

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GHS Hazard Pictograms

H225

Hazard Statement

H225 Highly Flammable liquid and vapor
Flammable liquids

Hazard Class

Class 3 Class 3

Sensitiveness

Moisture Sensitive

Synonyms & References

English

NSC-96780
SCHEMBL338658
LXX47M44WG
Acetic acid, TMS derivative
Acetic Acid Trimethylsilyl Ester
Silanol, trimethyl-, acetate
o-trimethylsilylacetate
Silanol, 1,1,1-trimethyl-, 1-acetate
TMSOAc
Trimethylsilyl acetate
Silanol, acetate
E75967
FT-0653703
2754-27-0
Trimethylacetoxysilane
NSC 96780
Ethyl (2E)-2-cyano-3-(1H-indolyl-3-yl)acrylate
CS-W011087
Trimethylsilyl acetate
CH3COOSi(CH3)3
EINECS 220-404-2
AKOS015892883
trimethylsilyl ethanoate
J-802297
NS00049728
S00009
CAA75427
TRIMETHYLSILYLACETATE
Trimethylsilyl acetate, 97%
UNII-LXX47M44WG
FS-3997

MDL Number

MFCD00008695

Customs Code

2931900090

FAQ

What regulatory guidelines apply to Trimethylsilyl acetate (CAS: 2754-27-0)?

Trimethylsilyl acetate (CAS: 2754-27-0) falls under the regulation of the Globally Harmonized System of Classification and Labelling of Chemicals (GHS). It should be handled according to specific GHS classifications, which include health and environmental hazards. Additionally, it is covered by the Registration, Evaluation, Authorisation and Restriction of Chemicals (REACH) regulations in the European Union. For FDA and EPA requirements, it should comply with the safety data sheet (SDS) recommendations and proper labeling for transportation and storage.

Are there alternatives to Trimethylsilyl acetate (CAS: 2754-27-0) in synthesis?

In synthesis, Trimethylsilyl acetate (CAS: 2754-27-0) can be replaced by similar functional group modifiers like tert-butyldimethylsilyl acetate or trifluoromethanesulfonyl chloride. These alternatives offer similar reactivity for silylation reactions but may have different handling and regulatory requirements.

What is the market or research trend for Trimethylsilyl acetate (CAS: 2754-27-0)?

The market for Trimethylsilyl acetate (CAS: 2754-27-0) is driven by its use in organic synthesis, particularly in protecting groups and derivatization reactions. Research trends focus on its applications in analytical chemistry and as a reagent for silylation. Market dynamics are influenced by cost, availability, and emerging technologies in chemical synthesis.

How should waste containing Trimethylsilyl acetate (CAS: 2754-27-0) be handled?

Waste containing Trimethylsilyl acetate (CAS: 2754-27-0) should be collected in appropriate, leak-proof containers and disposed of through professional waste disposal services. Incineration is a common method, but it must be done in compliance with local regulations. Environmental protection measures should be taken to prevent pollution, and appropriate protective gear should be used during handling and disposal to ensure safety.