[1,2,4]Triazolo[4,3-a]pyrazine

Basic Information

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CAS Number

274-82-8

Molecular Formula

C5H4N4

Molecular Weight

120.11 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

SMILES

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C1=CN2C=NN=C2C=N1

InChI

InChI=1S/C5H4N4/c1-2-9-4-7-8-5(9)3-6-1/h1-4H

InChIKey

NVSPJDGXKBDYIZ-UHFFFAOYSA-N

LogP

0.12429999999999986

Topological Polar Surface Area

43.08 Å²

Hydrogen Bond Donor/Acceptor

0 / 4

Complexity

105

Synonyms & References

English

Z1182328459
CS-0044086
AML0039
DTXSID80290402
EN300-75611
SY011971
SCHEMBL665488
[1,2,4]triazolo[4,3-a]pyrazine
A819088
J-503788
s-Triazolo[4,3-a]pyrazine
NSC68466
DS-16350
1,2,4-Triazolo[4,3-a]pyrazine
274-82-8
MFCD10574954
NSC-68466
(4S)-[1,2,4]triazolo[4,3-a]pyrazine
SVI
[1,2,4]Triazolo[4,3-a]pyrazine,98.5%
FT-0688011
1,4-Triazolo[4,3-a]pyrazine
OSM-S-610
AKOS006282811
[1,2,4]Triazolo[4,3-a]pyrazine
1,2,4]TRIAZOLO[4,3-A]PYRAZINE
1,2,4-Triazolo[4,3-a]pyrazine(9CI)
[1,2,4]triazolo[3,4-a]pyrazine
s-Triazolo<4,3-a>pyrazin
NVSPJDGXKBDYIZ-UHFFFAOYSA-N
4860AJ

MDL Number

MFCD10574954

Customs Code

2933990090

FAQ

What are the physical and chemical properties of [1,2,4]Triazolo[4,3-a]pyrazine (CAS: 274-82-8)?

[1,2,4]Triazolo[4,3-a]pyrazine is a solid with a crystalline form. Its molecular weight is approximately 180.17 g/mol. It is poorly water-soluble but soluble in organic solvents such as dimethylformamide and acetone. Chemically, it is stable under normal conditions but can react with strong acids or bases. It is a heterocyclic compound with potential for use in pharmaceuticals and other industries.

How is [1,2,4]Triazolo[4,3-a]pyrazine (CAS: 274-82-8) typically synthesized?

[1,2,4]Triazolo[4,3-a]pyrazine can be synthesized through multistep reactions involving diazotization and cyclization. Common starting materials include hydrazines and nitroaromatics. The synthesis typically involves the use of concentrated nitric acid as a catalyst. The yield of the product can be improved by careful control of reaction conditions, ensuring high selectivity and purity.

What industries use [1,2,4]Triazolo[4,3-a]pyrazine (CAS: 274-82-8)?

[1,2,4]Triazolo[4,3-a]pyrazine is primarily used in the pharmaceutical industry due to its potential as a drug candidate. It is also explored in the field of sensors for its unique spectroscopic properties. Additionally, it has potential applications in semiconductor materials and polymer science, though these areas are less common and are still under research.

What precautions should be taken when handling [1,2,4]Triazolo[4,3-a]pyrazine (CAS: 274-82-8)?

When handling [1,2,4]Triazolo[4,3-a]pyrazine, it is essential to use appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Ensure the use of a fume hood to avoid inhalation risks. Spills should be cleaned up immediately with appropriate absorbents, and the area should be well-ventilated. Always refer to the Safety Data Sheet (SDS) for specific handling instructions and emergency procedures.