1H-Imidazo[4,5-c]pyridine

Basic Information

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CAS Number

272-97-9

Molecular Formula

C6H5N3

Molecular Weight

119.13 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

Melting Point

168-172 °C

Boiling Point

425.1°Cat760mmHg

Flash Point

224.4°C

Refractive Index

1.715

SMILES

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C1=CN=CC2=C1N=CN2

InChI

InChI=1S/C6H5N3/c1-2-7-3-6-5(1)8-4-9-6/h1-4H,(H,8,9)

InChIKey

UBOOKRVGOBKDMM-UHFFFAOYSA-N

LogP

0.9578999999999998

Topological Polar Surface Area

41.57 Å²

Hydrogen Bond Donor/Acceptor

1 / 3

Complexity

105

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

SCHEMBL67119
NSC 521774
CHEMBL286232
A811184
3H-Imidazo[4 pound not5-c]pyridine
1H-Imidazo[4,5-c]pyridine
AKOS005207257
imidazo[4,5-c]pyridin
C6H5N3
3,5-DIAZAINDOLE
272-97-9
EN300-88369
NSC-521774
1H-Imidazo(4,5-c)pyridine
NS00010765
CL3548
SY021418
5-Azabenzimidazole
5-Aza-benzimidazole
1H-imidazo[4,5-c]pyridin
PB20239
YTTRIUMSULFATEOCTAHYDRATE
J-512590
Z1117890443
AMY5361
AS-20058
J-504666
NSC521774
5H-IMIDAZO[4,5-C]PYRIDINE
FT-0620034
MFCD00051808

MDL Number

MFCD08062980

Customs Code

2933990090

FAQ

What are the physical and chemical properties of 1H-Imidazo[4,5-c]pyridine (CAS: 272-97-9)?

1H-Imidazo[4,5-c]pyridine is a crystalline solid with a molecular weight of approximately 153.15 g/mol. It shows moderate solubility in common organic solvents like ethanol and acetone. Chemically, it is relatively stable but can undergo nucleophilic substitution reactions. It is generally soluble in polar aprotic solvents and slightly soluble in water.

How is 1H-Imidazo[4,5-c]pyridine (CAS: 272-97-9) typically synthesized?

1H-Imidazo[4,5-c]pyridine is typically synthesized via the condensation of 1H-imidazole and 2-pyridinemethanol. Common methods include the use of acetic acid as a solvent with heating, or using sodium hydride as a base. The reaction is known to have good yield, with selectivity towards the desired product.

What industries use 1H-Imidazo[4,5-c]pyridine (CAS: 272-97-9)?

1H-Imidazo[4,5-c]pyridine is used in various industries. It is a key component in the synthesis of pharmaceuticals due to its potential as an antiviral agent. It also finds applications in the development of sensors, semiconductors, and as a precursor in the polymer industry for the creation of functional materials.

What precautions should be taken when handling 1H-Imidazo[4,5-c]pyridine (CAS: 272-97-9)?

When handling 1H-Imidazo[4,5-c]pyridine, it is crucial to wear appropriate personal protective equipment (PPE), including gloves and goggles. The compound should be stored in a cool, dry place, away from heat and ignition sources. In case of a spill, it should be cleaned up using appropriate absorbent materials. Always consult the Safety Data Sheet (SDS) for detailed safety information.