3-(1-Methyl-7-oxo-3-propyl-4,7-dihydro-1H-pyrazolo[4,3-d]pyrimidin-5-yl)-N-[2-(1-methyl-2-pyrrolidinyl)ethyl]-4-propoxybenzenesulfonamide | CAS No. 268203-93-6
3-(1-Methyl-7-oxo-3-propyl-4,7-dihydro-1H-pyrazolo[4,3-d]pyrimidin-5-yl)-N-[2-(1-methyl-2-pyrrolidinyl)ethyl]-4-propoxybenzenesulfonamide
Basic Information
CAS Number
268203-93-6
Molecular Formula
C25H36N6O4S
Molecular Weight
516.67 g/mol
AD
Chemical Classification
Basic Physical Properties
Synonyms & References
English
- UDENAFIL [INN]
- L5IB4XLY36
- 5-[2-propyloxy-5-[2-(1-methyl-2-pyrrolidinyl)ethylaminosulfonyl]phenyl]-1-methyl-3-propyl-1,6-dihydro-7H-pyrazolo[4,3-d]pyrimidine-7-one
- Udenafil
- CID 6918523
- 3-(1-methyl-7-oxo-3-propyl-4,7-dihydro-1H-pyrazolo(4,3-d)pyrimidin-5-yl)-N-{2-((2RS)- 1-methylpyrrolidin-2-yl)ethyl}-4-propoxybenzenesulfonamide
- UDENAFIL [USAN]
- BENZENESULFONAMIDE, 3-(4,7-DIHYDRO-1-METHYL-7-OXO-3-PROPOXY-1H-PYRAZOLO(4,3-D)PYRIMIDIN-5-YL)-N-(2-(1-METHYL-2-PYRROLIDINYL)ETHYL)-4-PROPOXY-
- AKOS015902221
- 3-(1-methyl-7-oxo-3-propyl-4H-pyrazolo[4,3-d]pyrimidin-5-yl)-N-[2-(1-methylpyrrolidin-2-yl)ethyl]-4-propoxybenzenesulfonamide
- BDBM50602175
- AKOS040742801
- Udenafil (USAN/INN)
- SB17350
- BS-16833
- UDENAFIL [WHO-DD]
- SCHEMBL120993
- 3-(1-METHYL-7-OXO-3-PROPOXY-4,7-DIHYDRO-1H-PYRAZOLO(4,3-D)PYRIMIDIN-5-YL)-N-(2-(1-METHYLPYRROLIDIN-2-YL)ETHYL)-4-PROPOXYBENZENESULFONAMIDE
- Q4815980
- CHEBI:135926
- DA-8159
- 268203-93-6
- FT-0675724
- EX-A3836
- DB06267
- FT-0675725
- NS00010122
- 3-{1-methyl-7-oxo-3-propyl-1H,4H,7H-pyrazolo[4,3-d]pyrimidin-5-yl}-N-[2-(1-methylpyrrolidin-2-yl)ethyl]-4-propoxybenzene-1-sulfonamide
- DA8159DA8159
- DTXSID00870301
- Udenafil [USAN:INN]
MDL Number
MFCD20275557
FAQ
What are the physical and chemical properties of 3-(1-Methyl-7-oxo-3-propyl-4,7-dihydro-1H-pyrazolo[4,3-d]pyrimidin-5-yl)-N-[2-(1-methyl-2-pyrrolidinyl)ethyl]-4-propoxybenzenesulfonamide (CAS: 268203-93-6)?
The compound is a solid with a crystalline form. Its molecular weight is approximately 611.8 g/mol. It has a low solubility in water but good solubility in organic solvents such as methanol and dimethyl sulfoxide. The compound is moderately reactive and may undergo hydrolysis under basic conditions. It shows good stability under acidic conditions.
How is 3-(1-Methyl-7-oxo-3-propyl-4,7-dihydro-1H-pyrazolo[4,3-d]pyrimidin-5-yl)-N-[2-(1-methyl-2-pyrrolidinyl)ethyl]-4-propoxybenzenesulfonamide (CAS: 268203-93-6) typically synthesized?
The compound is synthesized through a multistep process involving condensation reactions, alkylation, and sulfonation. Typically, the key intermediate is synthesized using a palladium-catalyzed cross-coupling reaction followed by sulfonation with sulfur trioxide. The overall yield is around 65%, and the product is isolated by column chromatography after purification.
What industries use 3-(1-Methyl-7-oxo-3-propyl-4,7-dihydro-1H-pyrazolo[4,3-d]pyrimidin-5-yl)-N-[2-(1-methyl-2-pyrrolidinyl)ethyl]-4-propoxybenzenesulfonamide (CAS: 268203-93-6)?
The compound is primarily used in the pharmaceutical industry for its potential as a medicinal agent. It may also find applications in polymer synthesis as a functional monomer and in the development of sensors for detecting specific molecules. Additionally, it could be relevant in the semiconductor industry for use in certain materials or as a component in device fabrication processes.
What precautions should be taken when handling 3-(1-Methyl-7-oxo-3-propyl-4,7-dihydro-1H-pyrazolo[4,3-d]pyrimidin-5-yl)-N-[2-(1-methyl-2-pyrrolidinyl)ethyl]-4-propoxybenzenesulfonamide (CAS: 268203-93-6)?
When handling the compound, it is essential to wear appropriate personal protective equipment (PPE) including gloves, safety glasses, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood to minimize inhalation risks. Spills should be cleaned up using appropriate absorbent materials and disposed of according to local hazardous waste regulations. Always consult the Safety Data Sheet (SDS) for detailed handling and disposal procedures.
Related Compounds
![N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure](https://static.chemtradehub.com/structs/103/103687-96-3-8086.webp "N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure")
N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine
CAS Number:
103687-96-3
Molecular Formula:
C17H19NO5S
![5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure](https://static.chemtradehub.com/structs/112/112897-99-1-d1f4.webp "5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure")
5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine
CAS Number:
112897-99-1
Molecular Formula:
C30H31N3O7
![(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure](https://static.chemtradehub.com/structs/121/121055-10-5-583d.webp "(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure")
(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile
CAS Number:
121055-10-5
Molecular Formula:
C17H17NO4
![Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure](https://static.chemtradehub.com/structs/126/1263059-26-2-d6da.webp "Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure")
Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate
CAS Number:
1263059-26-2
Molecular Formula:
C8H6ClN3O2
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