(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(4-acetamidophenyl)propanoic acid | CAS No. 265321-34-4

(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(4-acetamidophenyl)propanoic acid

Basic Information

CAS Number

265321-34-4

Molecular Formula

C26H24N2O5

Molecular Weight

444.49 g/mol

AD

Basic Physical Properties

CC(=O)NC1=CC=C(C=C1)CC(C(=O)O)NC(=O)OCC2C3=CC=CC=C3C4=CC=CC=C24

InChI

InChI=1S/C26H24N2O5/c1-16(29)27-18-12-10-17(11-13-18)14-24(25(30)31)28-26(32)33-15-23-21-8-4-2-6-19(21)20-7-3-5-9-22(20)23/h2-13,23-24H,14-15H2,1H3,(H,27,29)(H,28,32)(H,30,31)/t24-/m0/s1

InChIKey

OJDKWDQVBLTUAW-DEOSSOPVSA-N

LogP

4.179400000000004

Topological Polar Surface Area

104.72999999999999 Ų

Hydrogen Bond Donor/Acceptor

3 / 7

Complexity

683

Synonyms & References

English

  • (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(4-acetamidophenyl)propanoic acid
  • (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)-amino)-3-(4-acetamidophenyl)propanoic acid
  • Fmoc-L-4-acetamidophe
  • 4-(Acetylamino)-N-Fmoc-L-phenylalanine
  • (2S)-3-(4-acetamidophenyl)-2-(9H-fluoren-9-ylmethoxycarbonylamino)propanoic acid
  • 265321-34-4
  • (2S)-3-(4-ACETAMIDOPHENYL)-2-{[(9H-FLUOREN-9-YLMETHOXY)CARBONYL]AMINO}PROPANOIC ACID
  • SCHEMBL25356445
  • MFCD01632242
  • CS-0336117
  • Fmoc-L-4-acetamidophenylalanine (Fmoc-L-Phe(4-NHAc)-OH)
  • (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(4-acetamidophenyl)propanoicacid
  • 4-Acetamido-N-{[(9H-fluoren-9-yl)methoxy]carbonyl}-L-phenylalanine
  • FMOC-L-PHE(4-NHAC)
  • DTXSID90719316
  • AKOS015948787
  • PS-12422

MDL Number

MFCD01632242

FAQ

What regulatory guidelines apply to (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(4-acetamidophenyl)propanoic acid (CAS: 265321-34-4)?

Regulatory guidelines for (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(4-acetamidophenyl)propanoic acid (CAS: 265321-34-4) include GHS classification, REACH regulations, FDA/EPA related requirements, and OSHA guidelines for handling and disposal. This compound is classified under GHS as a category 3 skin irritant and category 1A respiratory sensitizer. REACH requires manufacturers and importers to register this substance if the annual manufactured or imported quantity exceeds one tonne. FDA and EPA regulations dictate proper storage, handling, and disposal to ensure environmental and occupational safety.

Are there alternatives to (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(4-acetamidophenyl)propanoic acid (CAS: 265321-34-4) in synthesis?

Alternatives to (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(4-acetamidophenyl)propanoic acid (CAS: 265321-34-4) in synthesis include (R)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(4-acetamidophenyl)propanoic acid and related 9-fluorenylmethoxycarbonyl (Fmoc) derivatives. Common alternative reagents include chloride derivatives and other protected amino acid precursors. These alternatives offer similar functionality but may differ in reactivity and synthesis conditions.

What is the market or research trend for (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(4-acetamidophenyl)propanoic acid (CAS: 265321-34-4)?

The market and research trend for (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(4-acetamidophenyl)propanoic acid (CAS: 265321-34-4) is currently driven by its use in peptide synthesis and pharmaceutical applications, particularly for intermediates in drug discovery. Market trends indicate increasing demand due to its unique protecting group properties. Research is focused on developing more efficient synthesis methods and exploring its potential in various therapeutic areas.

How should waste containing (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(4-acetamidophenyl)propanoic acid (CAS: 265321-34-4) be handled?

Waste containing (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(4-acetamidophenyl)propanoic acid (CAS: 265321-34-4) should be collected in suitable, labeled containers and stored in a secure environment to prevent spillage. Proper disposal methods include incineration or professional waste disposal services. Environmental protection precautions include ensuring that waste does not enter waterways or soil. Compliance with local and national regulations for hazardous waste management is essential.

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