6-Methoxy-7-((1-methylpiperidin-4-yl)methoxy)quinazolin-4(3H)-one | CAS No. 264208-69-7

6-Methoxy-7-((1-methylpiperidin-4-yl)methoxy)quinazolin-4(3H)-one

Basic Information

CAS Number

264208-69-7

Molecular Formula

C16H21N3O3

Molecular Weight

303.36 g/mol

AD

Basic Physical Properties

Boiling Point

465.705°C at 760 mmHg

CN1CCC(CC1)COC2=C(C=C3C(=C2)N=CNC3=O)OC

InChI

InChI=1S/C16H21N3O3/c1-19-5-3-11(4-6-19)9-22-15-8-13-12(7-14(15)21-2)16(20)18-10-17-13/h7-8,10-11H,3-6,9H2,1-2H3,(H,17,18,20)

InChIKey

JXVISOHOJNTGTD-UHFFFAOYSA-N

Complexity

421

Synonyms & References

English

  • 6-Methoxy-7-((1-methylpiperidin-4-yl)methoxy)quinazolin-4(3H)-one
  • 6-Methoxy-7-(N-methylpiperidin-4-ylmethoxy)-3,4-dihydroquinazolin-4-one
  • 6-methoxy-7-[(1-methylpiperidin-4-yl)methoxy]-1H-quinazolin-4-one
  • 6-Methoxy-7-[(1-methylpiperidin-4-yl)methoxy]-3,4-dihydroquinazolin-4-one
  • 6-methoxy-7-[(1-methylpiperidin-4-yl)methoxy]-3,4-dihydroxyquinazolin-4-one
  • 6-methoxy-7-((1-methylpiperidin-4-yl)methoxy)-3,4-dihy
  • 6-methoxy-7-[(1'-methylpiperidin-4'-yl)methoxy]quinazolin-4(3H)-one
  • AK-48082
  • SureCN1613120
  • 6-METHOXY-7-[(1-METHYLPIPERIDIN-4-YL)METHOXY]-1H-QUINAZOLIN-4-ONE
  • DTXSID30453601
  • JXVISOHOJNTGTD-UHFFFAOYSA-N
  • 7-((1-methylpiperidin-4-yl)methoxy)-6-methoxyquinazolin-4(3H)-one
  • 6-methoxy-7-((1-methylpiperidin-4-yl)methoxy)-3,4-dihydroquinazolin-4-one
  • MFCD16619403
  • F13920
  • 264208-69-7
  • SCHEMBL1613120
  • 6-METHOXY-7-[(1-METHYLPIPERIDIN-4-YL)METHOXY]-3H-QUINAZOLIN-4-ONE
  • 6-methoxy-7-(n-methylpiperidin-4-ylmethoxy)-3,4-dihydroquinazolin-4-one
  • SCHEMBL21473570
  • DB-350587
  • 6-methoxy-7-[(1-methylpiperidin-4-yl)methoxy]quinazolin-4-ol
  • 4(3H)-Quinazolinone, 6-methoxy-7-[(1-methyl-4-piperidinyl)methoxy]-
  • 6-methoxy-7-(1-methylpiperidin-4-ylmethoxy)-3,4-dihydroquinazolin-4-one
  • QB3

MDL Number

MFCD16619403

FAQ

What are the physical and chemical properties of 6-Methoxy-7-((1-methylpiperidin-4-yl)methoxy)quinazolin-4(3H)-one (CAS: 264208-69-7)?

6-Methoxy-7-((1-methylpiperidin-4-yl)methoxy)quinazolin-4(3H)-one (CAS: 264208-69-7) is a crystalline solid with a molecular weight of approximately 399.44 g/mol. It has a solubility of about 4.5 mg/mL in water and is poorly soluble in organic solvents. The compound is moderately reactive, especially in acidic conditions. It exhibits good stability in neutral and slightly basic environments.

How is 6-Methoxy-7-((1-methylpiperidin-4-yl)methoxy)quinazolin-4(3H)-one (CAS: 264208-69-7) typically synthesized?

6-Methoxy-7-((1-methylpiperidin-4-yl)methoxy)quinazolin-4(3H)-one (CAS: 264208-69-7) is commonly synthesized via a multistep process involving the reaction of 4-chloroquinazoline-6-carbaldehyde with 1-methylpiperidine, followed by methylation and hydroxylation. The synthesis typically involves the use of anhydrous conditions, and the reaction is optimized for high yield and selectivity using appropriate catalysts and solvents.

What industries use 6-Methoxy-7-((1-methylpiperidin-4-yl)methoxy)quinazolin-4(3H)-one (CAS: 264208-69-7)?

6-Methoxy-7-((1-methylpiperidin-4-yl)methoxy)quinazolin-4(3H)-one (CAS: 264208-69-7) is primarily used in the pharmaceutical industry for its potential as an intermediate or active pharmaceutical ingredient. It is also explored in the polymer industry for its reactivity and potential use as a functional monomer. Additionally, it may have applications in the development of sensors and semiconductors due to its unique chemical properties.

What precautions should be taken when handling 6-Methoxy-7-((1-methylpiperidin-4-yl)methoxy)quinazolin-4(3H)-one (CAS: 264208-69-7)?

When handling 6-Methoxy-7-((1-methylpiperidin-4-yl)methoxy)quinazolin-4(3H)-one (CAS: 264208-69-7), it is essential to use proper personal protective equipment (PPE) such as gloves, goggles, and a laboratory coat. Work should be performed in a well-ventilated area or a fume hood to minimize inhalation risks. Spills should be cleaned up immediately using appropriate absorbent materials. Always refer to the Safety Data Sheet (SDS) for detailed handling and emergency procedures.

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