3-Methoxy-2-methylpyridine

Basic Information

View in Editor

CAS Number

26395-26-6

Molecular Formula

C7H9NO

Molecular Weight

123.15 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

SMILES

View in Editor

CC1=C(C=CC=N1)OC

InChI

InChI=1S/C7H9NO/c1-6-7(9-2)4-3-5-8-6/h3-5H,1-2H3

InChIKey

QRCUQLANPHYVEH-UHFFFAOYSA-N

LogP

1.39862

Topological Polar Surface Area

22.12 Å²

Hydrogen Bond Donor/Acceptor

0 / 2

Complexity

Synonyms & References

English

3-methoxy-2-methyl-pyridine
NS00028104
Pyridine, 3-methoxy-2-methyl-
2-methyl-3-methoxypyridine
A818423
AB03569
3-Methoxy-2-picoline
AMY6257
2-BROMO-4,6-DINITROBENZOICACID
26395-26-6
AS-41780
Pyridine,3-methoxy-2-methyl-
SCHEMBL1179274
MFCD00128178
CS-0197095
DTXSID00180997
FT-0654217
3-Methoxy-2-methylpyridine
AKOS006272152
EINECS 247-652-4
EN300-177112
Z1198150814
QRCUQLANPHYVEH-UHFFFAOYSA-N
3-METHOXY-2-PICOLINE
2,4-D AMINE SALT
2-Methyl-3-methoxypyridin
3-Methoxy-2-methyl-pyridin
3-methoxypicoline

MDL Number

MFCD00128178

Customs Code

2933399090

FAQ

What are the physical and chemical properties of 3-Methoxy-2-methylpyridine (CAS: 26395-26-6)?

3-Methoxy-2-methylpyridine (CAS: 26395-26-6) is a crystalline solid with a molecular weight of approximately 137.15 g/mol. It is sparingly soluble in water but soluble in common organic solvents such as ethanol and acetone. Chemically, it is moderately reactive, particularly towards nucleophiles and reducing agents. It is stable under normal conditions but should be stored in a cool, dry place away from direct sunlight.

How is 3-Methoxy-2-methylpyridine (CAS: 26395-26-6) typically synthesized?

3-Methoxy-2-methylpyridine (CAS: 26395-26-6) is typically synthesized via the methylation of 2-methylpyridine with methanol in the presence of an acid catalyst such as hydrochloric acid. The reaction is carried out under reflux conditions, and the product isolation involves simple distillation or recrystallization, yielding a yield of about 85%.

What industries use 3-Methoxy-2-methylpyridine (CAS: 26395-26-6)?

3-Methoxy-2-methylpyridine (CAS: 26395-26-6) is used in various industries, including pharmaceuticals and fine chemicals. It serves as a precursor in the synthesis of medicinal compounds and also finds applications in the production of dyes, polymers, and as a solvent in organic synthesis. Additionally, it is used in the fabrication of electronic materials and sensors.

What precautions should be taken when handling 3-Methoxy-2-methylpyridine (CAS: 26395-26-6)?

When handling 3-Methoxy-2-methylpyridine (CAS: 26395-26-6), appropriate personal protective equipment (PPE) should be worn, including gloves, goggles, and a laboratory coat. It should be stored in a cool, dry place away from direct sunlight and flammable materials. In case of spillage, it should be carefully cleaned up using appropriate methods. Always refer to the Safety Data Sheet (SDS) for detailed instructions on handling and storage.