1,1-Propanediol

Basic Information

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CAS Number

26264-14-2

Molecular Formula

C3H8O2

Molecular Weight

76.1 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Hydrocarbons

Basic Physical Properties

SMILES

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OCCCO

InChI

InChI=1S/C3H8O2/c1-2-3(4)5/h3-5H,2H2,1H3

InChIKey

ULWHHBHJGPPBCO-UHFFFAOYSA-N

LogP

-0.6389

Topological Polar Surface Area

40.46 Å²

Hydrogen Bond Donor/Acceptor

2 / 2

Synonyms & References

English

Propanediol
Dihydroxypropane
propylene glycol usp
(+/-)-Propylene glycol
Propylene glycol
propane-1,1-diol

MDL Number

MFCD07371109

FAQ

What are the physical and chemical properties of 1,1-Propanediol (CAS: 26264-14-2)?

1,1-Propanediol (CAS: 26264-14-2) is a colorless, viscous liquid with a slightly sweet taste. Its molecular weight is approximately 76.11 g/mol. It has a high solubility in water and organic solvents. Chemically, it is highly reactive and can participate in esterification and polymerization reactions. It crystallizes in the form of colorless needles at -11°C.

How is 1,1-Propanediol (CAS: 26264-14-2) typically synthesized?

1,1-Propanediol (CAS: 26264-14-2) can be synthesized through the hydration of propylene oxide, with a high selectivity of up to 99%. Alternatively, it can be produced from the biological fermentation of sugars, which provides a more sustainable route. The process often involves the use of catalysts like sulfuric acid or sodium hydroxide to enhance the reaction efficiency.

What industries use 1,1-Propanediol (CAS: 26264-14-2)?

1,1-Propanediol (CAS: 26264-14-2) is widely used in the pharmaceutical, polymer, and chemical industries. In pharmaceuticals, it serves as a solvent and a starting material for drug synthesis. In polymers, it is used in the production of polyurethane and polyester resins. Additionally, it is employed in the manufacturing of sensors and semiconductors for its excellent solubility and reactivity.

What precautions should be taken when handling 1,1-Propanediol (CAS: 26264-14-2)?

When handling 1,1-Propanediol (CAS: 26264-14-2), it is essential to wear personal protective equipment (PPE) such as gloves, safety goggles, and a lab coat. Ensure the area is well-ventilated and consider using a fume hood to minimize exposure. Spills should be cleaned up immediately using appropriate absorbent materials. Always consult the Safety Data Sheet (SDS) for specific handling and storage instructions and follow all laboratory safety guidelines.