Fosfomycin sodium

Basic Information

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CAS Number

26016-99-9

Molecular Formula

C3H5Na2O4P

Molecular Weight

182.02 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Agricultural Chemicals Pesticides Insecticides

Water Treatment Chemicals Coagulants and Flocculants Inorganic Coagulants

Basic Physical Properties

Melting Point

>300°C

Boiling Point

342.7ºC at 760 mmHg

Water Solubility

Freely soluble in water or aqueous solution

Flash Point

161ºC

Solubility

H2O: 50 mg/mL, clear, colorless

Specific Rotation

-3.98° (c = 5, H2O)

SMILES

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CC1C(O1)P(=O)([O-])[O-].[Na+].[Na+]

InChI

InChI=1S/C3H7O4P.2Na/c1-2-3(7-2)8(4,5)6;;/h2-3H,1H3,(H2,4,5,6);;/q;2*+1/p-2/t2-,3+;;/m0../s1

InChIKey

QZIQJIKUVJMTDG-JSTPYPERSA-L

LogP

0.78530

Complexity

127

Safety Information

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GHS Hazard Pictograms

H303

Hazard Statement

H303 May be harmful if swallowed
Acute toxicity, oral

Synonyms & References

English

disodium;[(2R,3S)-3-methyloxiran-2-yl]-dioxido-oxo-lambda5-phosphane
Disodium phosphonomycin
Disodium fosfomycin
Sodium fosfomycin
Fosfomycin sodium (JP17)
disodium [(2R,3S)-3-methyloxiran-2-yl]phosphonate
97MMO19FNO
NSC-136017
F0889
Phosphomycin disodium salt, antibacterial MurA inhibitor
AS-13713
Phosphonic acid,(3-methyloxiranyl)-,disodium salt,cis-(+-)-
25162-71-4
Disodium (1R,2S)-(1,2-epoxypropyl)phosphonate
Fosfocina disodium salt
EINECS 247-409-2
D02188
25030-61-9
QZIQJIKUVJMTDG-JSTPYPERSA-L
CCG-266439
Fosfomycin sodium
sodium ((2R,3S)-3-methyloxiran-2-yl)phosphonate
AS-11021
Levo-phosphonomycin disodium salt
Fosmicin S (TN)
Fosfomycin disodium salt
Phosphonic acid, (3-methyloxiranyl)-, disodium salt, (2R-cis)-
Fosmicin S
Phosphomycin disodium salt
CHEMBL1256140
Disodium (1R,2S)-1,2-Epoxypropylphosphonate

MDL Number

MFCD22741288

FAQ

What is Fosfomycin sodium (CAS: 26016-99-9)?

Fosfomycin sodium (CAS: 26016-99-9) is an antibiotic used to combat bacterial infections. Its chemical formula is C8H15NO6P, and it appears as a white crystalline powder. It is highly soluble in water and has a molecular weight of 255.19 g/mol. Fosfomycin sodium works by inhibiting bacterial cell wall synthesis, making it effective against both Gram-positive and Gram-negative bacteria.

What are the main uses of Fosfomycin sodium (CAS: 26016-99-9)?

Fosfomycin sodium (CAS: 26016-99-9) is primarily used as an antibiotic to treat urinary tract infections, skin infections, and respiratory tract infections. It is also applied in veterinary medicine for livestock. In research, it serves as a tool to study antibiotic resistance mechanisms. Its broad-spectrum activity makes it valuable in pharmaceuticals and industrial applications for microbial control.

Is Fosfomycin sodium (CAS: 26016-99-9) safe?

Fosfomycin sodium (CAS: 26016-99-9) is generally safe when used as directed. It has low toxicity and is well-tolerated in most cases, though side effects like gastrointestinal discomfort may occur. Handling precautions include wearing gloves and avoiding inhalation or contact with eyes. Safety standards ensure it meets regulatory guidelines for pharmaceutical use, emphasizing proper administration and storage to maintain efficacy and minimize risks.

How should Fosfomycin sodium (CAS: 26016-99-9) be stored?

Fosfomycin sodium (CAS: 26016-99-9) should be stored in a cool, dry place, ideally at 2-8°C, to preserve stability. It is hygroscopic, so protection from moisture and light is essential. Store in airtight containers to prevent degradation. Proper storage conditions ensure optimal shelf life and effectiveness, as recommended by chemical safety protocols.