(5-Bromo-2-methylphenyl)methanol

Basic Information

View in Editor

CAS Number

258886-04-3

Molecular Formula

C8H9BrO

Molecular Weight

201.06 g/mol

Chemical Classification

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Melting Point

58.0 to 62.0 deg-C

SMILES

View in Editor

CC1=C(C=C(C=C1)Br)CO

InChI

InChI=1S/C8H9BrO/c1-6-2-3-8(9)4-7(6)5-10/h2-4,10H,5H2,1H3

InChIKey

CXASFBKJNJSOAI-UHFFFAOYSA-N

LogP

2.24982

Topological Polar Surface Area

20.23 Å²

Hydrogen Bond Donor/Acceptor

1 / 1

Complexity

105

Synonyms & References

English

(Benzenemethanol, 5-bromo-2-methyl- )
5-Bromo-2-methylbenzyl Alcohol
(5-bromo-2-methylphenyl)methanol
5-bromo-2-methylBenzenemethanol
BENZENEMETHANOL, 5-BROMO-2-METHYL-
5-bromo-2-methylbenzylalcohol
(5-Bromo-2-methyl-phenyl)-methanol
CXASFBKJNJSOAI-UHFFFAOYSA-N
Benzenemethanol,5-bromo-2-methyl-
Z0434
F10103
SCHEMBL606473
CS-W000524
F15583
5-bromo-2-methylbenzyl alcohol
DA-37813
(5-BROMO-2-METHYLPHENYL)METHANOL
SY153594
Z1259109160
258886-04-3
AMY39689
DTXSID10514547
TS-02855
AB87965
A903110
B5037
EN300-133496
AKOS014642054
MFCD12031921
5-bromo-2-methylbenzenemethanol

MDL Number

MFCD12031921

FAQ

What are the physical and chemical properties of (5-Bromo-2-methylphenyl)methanol (CAS: 258886-04-3)?

(5-Bromo-2-methylphenyl)methanol (CAS: 258886-04-3) is a colorless liquid with a molecular weight of approximately 220.03 g/mol. It has a low solubility in water but is more soluble in organic solvents. This compound is known for its reactivity towards electrophiles and nucleophiles, and it can undergo substitution reactions such as bromination and methylation. It is typically stored in a cool, dark place to prevent photodegradation.

How is (5-Bromo-2-methylphenyl)methanol (CAS: 258886-04-3) typically synthesized?

(5-Bromo-2-methylphenyl)methanol (CAS: 258886-04-3) is commonly synthesized through a bromination of 2-methylphenol in the presence of a catalyst such as N-bromosuccinimide (NBS). This process involves a electrophilic aromatic substitution followed by a hydroxylation step to introduce the alcohol functionality. Typical yields range from 50-70%, and the reaction is monitored using thin-layer chromatography (TLC).

What industries use (5-Bromo-2-methylphenyl)methanol (CAS: 258886-04-3)?

(5-Bromo-2-methylphenyl)methanol (CAS: 258886-04-3) is primarily used in the pharmaceutical and chemical industries. It serves as a key intermediate in the synthesis of various drugs and organic compounds. Additionally, it is utilized in the production of polymers and in the development of sensors and semiconductors for electronic applications. Its versatility makes it a valuable compound in these and related fields.

What precautions should be taken when handling (5-Bromo-2-methylphenyl)methanol (CAS: 258886-04-3)?

When handling (5-Bromo-2-methylphenyl)methanol (CAS: 258886-04-3), it is essential to use personal protective equipment (PPE) such as gloves, goggles, and a lab coat. This compound should be stored in a cool, dark place, and fume hoods should be used during handling to minimize exposure. In case of a spill, neutralize it with an appropriate agent and clean up using absorbent material. Refer to the safety data sheet (SDS) for detailed emergency procedures and storage recommendations.