Glycylglycyl-L-valyl-L-leucyl-L-valyl-L-glutaminyl-L-prolylglycine | CAS No. 258818-34-7

Glycylglycyl-L-valyl-L-leucyl-L-valyl-L-glutaminyl-L-prolylglycine

Basic Information

CAS Number

258818-34-7

Molecular Formula

C32H55N9O10

Molecular Weight

725.85 g/mol

AD

Basic Physical Properties

CC(C)CC(C(=O)NC(C(C)C)C(=O)NC(CCC(=O)N)C(=O)N1CCCC1C(=O)NCC(=O)O)NC(=O)C(C(C)C)NC(=O)CNC(=O)CN

InChI

InChI=1S/C32H55N9O10/c1-16(2)12-20(38-30(49)26(17(3)4)39-24(44)14-35-23(43)13-33)28(47)40-27(18(5)6)31(50)37-19(9-10-22(34)42)32(51)41-11-7-8-21(41)29(48)36-15-25(45)46/h16-21,26-27H,7-15,33H2,1-6H3,(H2,34,42)(H,35,43)(H,36,48)(H,37,50)(H,38,49)(H,39,44)(H,40,47)(H,45,46)/t19-,20-,21-,26-,27-/m0/s1

InChIKey

ORFLZNAGUTZRLQ-ZMBVWFSWSA-N

LogP

-3.184100000000007

Topological Polar Surface Area

301.31999999999994 Ų

Hydrogen Bond Donor/Acceptor

11 / 19

Complexity

1290

Synonyms & References

English

  • Larazotide (USAN/INN)
  • AT 2347
  • H-Gly-Gly-Val-Leu-Val-Gln-Pro-Gly-OH
  • D09351
  • Larazotide
  • DTXSID30180526
  • AKOS040741937
  • 258818-34-7 (free base)
  • ZN3R5560ZV
  • Larazotide [USAN:INN]
  • UNII-ZN3R5560ZV
  • CHEBI:177799
  • 2-[[(2S)-1-[(2S)-5-amino-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[2-[(2-aminoacetyl)amino]acetyl]amino]-3-methylbutanoyl]amino]-4-methylpentanoyl]amino]-3-methylbutanoyl]amino]-5-oxopentanoyl]pyrrolidine-2-carbonyl]amino]acetic acid
  • CS-0025478
  • 258818-34-7
  • HY-106268
  • glycylglycyl-L-valyl-L-leucyl-L-valyl-L-glutaminyl-L-prolylglycine
  • Q27295752
  • DB05645
  • ORFLZNAGUTZRLQ-ZMBVWFSWSA-N
  • NS00072884
  • CHEMBL2105646
  • AT-2347
  • larazotide-acetate
  • 2-((S)-1-((2S,5S,8S,11S)-17-Amino-2-(3-amino-3-oxopropyl)-8-isobutyl-5,11-diisopropyl-4,7,10,13,16-pentaoxo-3,6,9,12,15-pentaazaheptadecan-1-oyl)pyrrolidine-2-carboxamido)acetic acid
  • SCHEMBL23668120
  • Glycylglycyl-L-valyl-L-leucyl-L-valyl-L-glutaminyl-L-prolylglycine
  • 2-[[(2S)-1-[(2S)-5-amino-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[2-[(2-aminoacetyl)amino]acetyl]amino]-3-methylbutanoyl]amino]-4-methylpentanoyl]amino]-3-methylbutanoyl]amino]-5-oxopentanoyl]pyrrolidine-2-carb

FAQ

What regulatory guidelines apply to Glycylglycyl-L-valyl-L-leucyl-L-valyl-L-glutaminyl-L-prolylglycine (CAS: 258818-34-7)?

Glycylglycyl-L-valyl-L-leucyl-L-valyl-L-glutaminyl-L-prolylglycine (CAS: 258818-34-7) falls under various regulatory guidelines such as REACH regulations for registration, evaluation, authorization, and restriction of chemicals in the EU. In the US, it is regulated by the FDA for pharmaceuticals and the EPA for environmental safety. Additionally, the compound may require classification and labeling under the GHS system according to its hazardous properties.

Are there alternatives to Glycylglycyl-L-valyl-L-leucyl-L-valyl-L-glutaminyl-L-prolylglycine (CAS: 258818-34-7) in synthesis?

In synthesis, Glycylglycyl-L-valyl-L-leucyl-L-valyl-L-glutaminyl-L-prolylglycine (CAS: 258818-34-7) can be replaced by similar peptides or synthetic peptides with similar sequences. Common alternative reagents include various amino acids and dipeptides. Additionally, chemists may use other solid-phase peptide synthesis techniques with different protecting groups or coupling methods.

What is the market or research trend for Glycylglycyl-L-valyl-L-leucyl-L-valyl-L-glutaminyl-L-prolylglycine (CAS: 258818-34-7)?

The market for Glycylglycyl-L-valyl-L-leucyl-L-valyl-L-glutaminyl-L-prolylglycine (CAS: 258818-34-7) is trending towards increased research and development in pharmaceutical and biotechnology applications. The compound is of interest in drug discovery and development, particularly for peptide-based therapies. Research trends include exploring its potential in treating diseases such as Alzheimer's, diabetes, and other neurological disorders.

How should waste containing Glycylglycyl-L-valyl-L-leucyl-L-valyl-L-glutaminyl-L-prolylglycine (CAS: 258818-34-7) be handled?

Waste containing Glycylglycyl-L-valyl-L-leucyl-L-valyl-L-glutaminyl-L-prolylglycine (CAS: 258818-34-7) should be collected in appropriate containers and disposed of according to local regulations. For small amounts, incineration is a common method. Professional waste disposal services can handle larger quantities or more hazardous materials. Environmental precautions include ensuring that all waste is properly labeled and stored to prevent contamination of water sources and soil.

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