Robenidine hydrochloride

Basic Information

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CAS Number

25875-50-7

Molecular Formula

C15H14Cl3N5

Molecular Weight

370.7 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Amines

Fine Chemicals Dyes and Pigments Organic Dyes

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Melting Point

252-254°C

Boiling Point

488.1 °C at 760 mmHg

Flash Point

249 °C

SMILES

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C1=CC(=CC=C1C=NNC(=NN=CC2=CC=C(C=C2)Cl)N)Cl.Cl

InChI

InChI=1S/C15H13Cl2N5.ClH/c16-13-5-1-11(2-6-13)9-19-21-15(18)22-20-10-12-3-7-14(17)8-4-12;/h1-10H,(H3,18,21,22);1H/b19-9+,20-10+;

InChIKey

LTWIBTYLSRDGHP-HCURTGQUSA-N

LogP

5.15890

Complexity

408

Safety Information

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GHS Hazard Pictograms

H302

Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

Synonyms & References

English

SCHEMBL3851893
Robenidine hydrochloride 100 microg/mL in Acetone:Methanol
CS-8206
DTXSID101017219
UNII-8STT15Y392
ROBENIDINE HYDROCHLORIDE [MI]
AC-6798
ROBENIDINE HYDROCHLORIDE [GREEN BOOK]
GUANIDINE, 1,3-BIS((p-CHLOROBENZYLIDENE)AMINO)-, MONOHYDROCHLORIDE
BS-42469
J-016154
HY-B2157
SCHEMBL23858320
1,3-Bis((p-chlorobenzylidene)amino)guanidine hydrochloride
Robenzidine
ROBENIDINE HYDROCHLORIDE [MART.]
Robenidine-d8 HCl
Robenidine HCl Vetranal
ROBENIDINE HYDROCHLORIDE (MART.)
Robenidine Hydrochoride
Robenidine hydrochloride, VETRANAL(TM), analytical standard
Hydrochloride, Robenidine
1,2-bis[(E)-(4-chlorophenyl)methylideneamino]guanidine;hydrochloride
N',2-Bis(4-chlorobenzylidene)hydrazine-1-carboximidhydrazide hydrochloride
AKOS015900430
CCG-268301
25875-50-7
1,2-bis[(4-chlorophenyl)methyleneamino]guanidine hydrochloride
A818057
1,3-Bis((p-chlorobenzylidene)amino)guanidine monohydrochloride
Robenidine hydrochloride [USAN]

MDL Number

MFCD01724404

FAQ

What is Robenidine hydrochloride (CAS: 25875-50-7)?

Robenidine hydrochloride (CAS: 25875-50-7) is a chemical compound commonly used in pharmaceutical applications. It has the molecular formula C19H23ClN2O and is known for its antihistaminic properties. This compound is typically a white to off-white crystalline powder with good solubility in water and organic solvents. It is often used as an intermediate in drug synthesis due to its stability and reactivity.

What are the main uses of Robenidine hydrochloride (CAS: 25875-50-7)?

Robenidine hydrochloride (CAS: 25875-50-7) is primarily used in the pharmaceutical industry as an antihistaminic agent. It serves as a precursor for the synthesis of various drugs, including antipsychotic medications. Additionally, it finds applications in research and development for studying drug interactions and biological activity. Its use in food and industrial sectors is limited due to regulatory and safety considerations.

Is Robenidine hydrochloride (CAS: 25875-50-7) safe?

Robenidine hydrochloride (CAS: 25875-50-7) is generally considered safe when handled properly. However, like many chemical compounds, it requires caution during use. It is advisable to follow standard safety protocols, including wearing appropriate personal protective equipment (PPE) such as gloves and goggles. Inhalation, ingestion, or skin contact should be avoided, and proper ventilation is recommended to minimize exposure risks.

How should Robenidine hydrochloride (CAS: 25875-50-7) be stored?

Robenidine hydrochloride (CAS: 25875-50-7) should be stored in a cool, dry, and dark place to maintain its stability. It is best kept in a sealed container at a temperature below 25°C and away from moisture and light. Proper storage conditions help preserve its chemical integrity and effectiveness, making it suitable for use in pharmaceutical and research settings.