(6alpha,11beta,16beta)-6,9-Difluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione | CAS No. 2557-49-5

(6alpha,11beta,16beta)-6,9-Difluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione

Basic Information

CAS Number

2557-49-5

Molecular Formula

C22H28F2O5

Molecular Weight

410.46 g/mol

AD

Basic Physical Properties

Melting Point

254-262°C

Boiling Point

569.8 oC at 760 mmHg

Density

1.36

Flash Point

298.4 oC

Refractive Index

1.579?

CC1CC2C3CC(C4=CC(=O)C=CC4(C3(C(CC2(C1(C(=O)CO)O)C)O)F)C)F

InChI

InChI=1S/C22H28F2O5/c1-11-6-13-14-8-16(23)15-7-12(26)4-5-19(15,2)21(14,24)17(27)9-20(13,3)22(11,29)18(28)10-25/h4-5,7,11,13-14,16-17,25,27,29H,6,8-10H2,1-3H3/t11-,13-,14-,16-,17-,19-,20-,21-,22-/m0/s1

InChIKey

WXURHACBFYSXBI-XHIJKXOTSA-N

LogP

1.8436999999999997

Topological Polar Surface Area

94.83 Ų

Hydrogen Bond Donor/Acceptor

3 / 5

Complexity

839

Safety Information

View Safety Information

Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation
H319 Causes serious eye irritation
Serious eye damage/eye irritation
H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

  • (1R,2S,8S,10S,11S,13S,14R,15S,17S)-1,8-difluoro-14,17-dihydroxy-14-(2-hydroxyacetyl)-2,13,15-trimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadeca-3,6-dien-5-one
  • D07AC10
  • Diflorasonum
  • Diflorasonum [INN-Latin]
  • AS-15781
  • DB00223
  • U 34865
  • Diflorasone [INN:BAN]
  • (6alpha,11beta,16beta)-6,9-difluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione
  • Diflorasona
  • CCG-268770
  • 6a,9a-difluoro-16b-methylprednisolone
  • AKOS025401541
  • T2DHJ9645W
  • Murode (TN)
  • (1R,2S,3aS,3bS,5S,9aS,9bR,10S,11aS)-5,9b-difluoro-1,10-dihydroxy-1-(2-hydroxyacetyl)-2,9a,11a-trimethyl-1H,2H,3H,3aH,3bH,4H,5H,7H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-7-one
  • [2-(Cyclohexylthio)-1H-benzimidazol-1-yl]-aceticacid
  • Q5275451
  • NS00069995
  • BCP29719
  • 6.ALPHA.,9-DIFLUORO-11.BETA.,17,21-TRIHYDROXY-16.BETA.-METHYLPREGNA-1,4-DIENE-3,20-DIONE
  • Diflorasona (INN-Spanish)
  • CHEBI:59750
  • Diflorasonum (INN-Latin)
  • CS-0017488
  • Q-101394
  • UNII-T2DHJ9645W
  • HY-A0158
  • s5360
  • (6S,8S,9R,10S,11S,13S,14S,16S,17R)-6,9-difluoro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one
  • SCHEMBL4555

MDL Number

MFCD00200358

Customs Code

2937229000

FAQ

What is (6alpha,11beta,16beta)-6,9-Difluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione (CAS: 2557-49-5)?

(6alpha,11beta,16beta)-6,9-Difluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione, also known as DHPG, is a synthetic steroid compound with a unique chemical structure. It is characterized by its fluoro and hydroxy groups, which contribute to its specific biological activities.

What are the main uses of (6alpha,11beta,16beta)-6,9-Difluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione (CAS: 2557-49-5)?

(6alpha,11beta,16beta)-6,9-Difluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione is primarily used as a research tool in endocrinology and pharmacology, particularly for studying steroid hormone receptors and their signaling pathways.

Is (6alpha,11beta,16beta)-6,9-Difluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione (CAS: 2557-49-5) safe?

Generally, (6alpha,11beta,16beta)-6,9-Difluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione is safe when handled with appropriate caution. However, it should be used and stored under controlled conditions to avoid inhalation, skin contact, and eye exposure. Protective measures such as gloves and goggles are recommended.

How should (6alpha,11beta,16beta)-6,9-Difluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione (CAS: 2557-49-5) be stored?

(6alpha,11beta,16beta)-6,9-Difluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione should be stored in a cool, dry place away from direct sunlight and heat sources. It should be kept in a tightly sealed container to prevent degradation. It is also important to ensure that the storage area is well-ventilated to avoid any potential inhalation risks.

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