3'-Deoxy-3'-fluorothymidine

Basic Information

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CAS Number

25526-93-6

Molecular Formula

C10H13FN2O4

Molecular Weight

244.22 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Specialty Chemicals UV Stabilizers

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Melting Point

176-178 °C

Boiling Point

°Cat760mmHg

Refractive Index

1.565

SMILES

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CC1=CN(C(=O)NC1=O)C2CC(C(O2)CO)F

InChI

InChI=1S/C10H13FN2O4/c1-5-3-13(10(16)12-9(5)15)8-2-6(11)7(4-14)17-8/h3,6-8,14H,2,4H2,1H3,(H,12,15,16)/t6-,7+,8+/m0/s1

InChIKey

UXCAQJAQSWSNPQ-XLPZGREQSA-N

LogP

-0.5370799999999998

Topological Polar Surface Area

84.32000000000001 Å²

Hydrogen Bond Donor/Acceptor

2 / 6

Complexity

385

Synonyms & References

English

1-[(2R,4S,5R)-4-fluoro-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione
DB06198
FddT
DRG-0097
3'F-TdR
NS00068737
CHEMBL105318
Alovudine
3''-Fluoro-2'',3''-dideoxythymidine
3-Deoxy-3-fluorothymidine
MFCD00056058
Alovudine (USAN/INN)
UXCAQJAQSWSNPQ-XLPZGREQSA-N
3'-Deoxy-3'-18F fluorothymidine
CS-0013305
SCHEMBL133722
FLT
Alovudine [USAN:INN]
Tox21_112376_1
MIV-310
1-(3'-Deoxy-3'-fluoro-beta-D-pentofuranosyl)thymine
s6848
BDBM50132287
CL-184,824
AS-60404
1-(3-fluoro-2,3-dideoxy-beta-D-erythro-pentofuranosyl)thymine
ALOVUDINE [USAN]
ALOVUDINE [INN]
UNII-PG53R0DWDQ
A817893
CAS-25526-93-6

MDL Number

MFCD00056058

FAQ

What regulatory guidelines apply to 3'-Deoxy-3'-fluorothymidine (CAS: 25526-93-6)?

3'-Deoxy-3'-fluorothymidine (CAS: 25526-93-6) falls under the scope of regulatory guidelines such as GHS classification for hazardous materials. It is also subject to REACH regulations in the European Union, requiring manufacturers to register the substance if the annual tonnage exceeds the threshold. Additionally, FDA and EPA regulations may apply in the United States, particularly for its use in pharmaceuticals and environmental releases.

Are there alternatives to 3'-Deoxy-3'-fluorothymidine (CAS: 25526-93-6) in synthesis?

Several alternatives to 3'-Deoxy-3'-fluorothymidine (CAS: 25526-93-6) exist in synthesis, including fluorodeoxyuridine and other 3'-deoxy analogs. Common alternative reagents such as 3'-deoxy-3'-bromothymidine can also be used depending on the specific synthesis requirements and desired outcomes.

What is the market or research trend for 3'-Deoxy-3'-fluorothymidine (CAS: 25526-93-6)?

The market for 3'-Deoxy-3'-fluorothymidine (CAS: 25526-93-6) is growing due to its potential applications in antiviral and antitumor drug development. Research trends indicate increasing focus on its use in targeted therapies and as an intermediate in the synthesis of complex organic compounds. Market trends show rising demand, particularly in pharmaceutical and chemical research sectors.

How should waste containing 3'-Deoxy-3'-fluorothymidine (CAS: 25526-93-6) be handled?

Waste containing 3'-Deoxy-3'-fluorothymidine (CAS: 25526-93-6) should be collected in appropriate containers and disposed of by incineration or professional waste disposal services. Environmental protection measures include proper sealing of waste to prevent leakage and ensuring that the disposal process complies with local and international regulations to minimize environmental impact.