Kanamycin A Sulfate

Basic Information

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CAS Number

25389-94-0

Molecular Formula

C18H38N4O15S

Molecular Weight

582.58 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Surfactants Anionic Surfactants

Laboratory Chemicals Research Chemicals Biochemical Reagents

Basic Physical Properties

Melting Point

250°C(dec.)

Boiling Point

No data available

Water Solubility

Soluble in water at 10mg/ml

Flash Point

No data available

Solubility

H2O: 10-50 mg/mL As a stock solution. Stock solutions should be stored at 2-8°C. Stable at 37°C for 5 days.

Refractive Index

117.5 ° (C=1, H2O)

Vapor Pressure

No data available

Specific Rotation

117.5° (c=1, H2O)

SMILES

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C1C(C(C(C(C1N)OC2C(C(C(C(O2)CN)O)O)O)O)OC3C(C(C(C(O3)CO)O)N)O)N.OS(=O)(=O)O

InChI

InChI=1S/C18H36N4O11.H2O4S/c19-2-6-10(25)12(27)13(28)18(30-6)33-16-5(21)1-4(20)15(14(16)29)32-17-11(26)8(22)9(24)7(3-23)31-17;1-5(2,3)4/h4-18,23-29H,1-3,19-22H2;(H2,1,2,3,4)/t4-,5+,6-,7-,8+,9-,10-,11-,12+,13-,14-,15+,16-,17-,18-;/m1./s1

InChIKey

OOYGSFOGFJDDHP-KMCOLRRFSA-N

LogP

-7.944200000000009

Topological Polar Surface Area

357.21 Å²

Hydrogen Bond Donor/Acceptor

17 / 19

Complexity

720

Safety Information

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GHS Hazard Pictograms

H360

Hazard Statement

H360 May damage fertility or the unborn child
Reproductive toxicity

Toxicity

LD50 in mice: 20.7 g/kg orally; 1450 mg/kg i.p. (Zel'tser)

Synonyms & References

English

Kanamycin acid sulfate
D03262
KUC109575AC
D-STREPTAMINE, O-3-AMINO-3-DEOXY-.ALPHA.-D-GLUCOPYRANOSYL(1->6)-O-(6-AMINO-6-DEOXY-.ALPHA.-D-GLUCOPYRANOSYL(1->4))-2-DEOXY-, SULFATE (1:1) (SALT)
Kannasyn
25389-94-0
Q27107073
EN300-19650841
KANAMYCIN SULFATE [VANDF]
HB4429
Kanamycin sulfate Streptomyces kanamyceticus, powder, gamma-irradiated
Kanamycin monosulfate
Ophtalmokalixan
D-Streptamine, O-3-amino-3-deoxy-alpha-D-glucopyranosyl(1->6)-O-(6-amino-6-deoxy-alpha-D-glucopyranosyl(1->4))-2-deoxy-, sulfate (1:1) (salt)
NS00081901
Kanamycin A sulphate
KANAMYCIN SULFATE [GREEN BOOK]
Kanacedin
NSC-757068
3847-27-6
Kano
HMS500B06
C18H36N4O11 .H2O4S
SCHEMBL65538
KANAMYCIN SULFATE [USP MONOGRAPH]
KANAMYCIN A SULFATE [MI]
D-STREPTAMINE, O-3-AMINO-3-DEOXY-.ALPHA.-D-GLUCOPYRANOSYL(1->6)-O-(6-AMINO-6-DEOXY-.ALPHA.-D-GLUCOPYRANOSYL(1->4))-2-DEOXY-, SULPHATE (1:1) (SALT)
Kanamycin A sulfate
(2R,3S,4S,5R,6R)-2-(aminomethyl)-6-[(1R,2R,3S,4R,6S)-4,6-diamino-3-[(2S,3R,4S,5S,6R)-4-amino-3,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-2-hydroxycyclohexyl]oxyoxane-3,4,5-triol;sulfuric acid
Cristalomicina
Cantrex

MDL Number

MFCD00070253

Customs Code

29419020

FAQ

What is Kanamycin A Sulfate (CAS: 25389-94-0)?

Kanamycin A Sulfate (CAS: 25389-94-0) is an antibiotic compound derived from Streptomyces kanamyceticus. It has the chemical formula C21H42N6O14S2 and is known for its amphoteric properties, meaning it can act as both an acid and a base. It is commonly used in pharmaceutical applications due to its broad-spectrum antimicrobial activity.

What are the main uses of Kanamycin A Sulfate (CAS: 25389-94-0)?

Kanamycin A Sulfate (CAS: 25389-94-0) is primarily used in the treatment of bacterial infections, particularly in veterinary medicine and human healthcare. It is also employed in research for studying antibiotic mechanisms and in industrial settings for producing other antibiotics and pharmaceutical intermediates.

Is Kanamycin A Sulfate (CAS: 25389-94-0) safe?

Kanamycin A Sulfate (CAS: 25389-94-0) is generally considered safe when used as directed, but it may cause ototoxicity and nephrotoxicity in high doses. Proper handling, including the use of personal protective equipment, is recommended to minimize exposure risks. It is regulated under safety standards for pharmaceutical and industrial use.

How should Kanamycin A Sulfate (CAS: 25389-94-0) be stored?

Kanamycin A Sulfate (CAS: 25389-94-0) should be stored in a cool, dry place away from direct light. It is typically kept in airtight containers to prevent moisture absorption. Storage conditions should maintain a temperature between 15°C to 25°C and ensure low humidity to preserve stability and potency.