1,1'-(1,4-Phenylene)bis(1H-imidazole)

Basic Information

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CAS Number

25372-07-0

Molecular Formula

C12H10N4

Molecular Weight

210.24 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

SMILES

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C1=CC(=CC=C1N2C=CN=C2)N3C=CN=C3

InChI

InChI=1S/C12H10N4/c1-2-12(16-8-6-14-10-16)4-3-11(1)15-7-5-13-9-15/h1-10H

InChIKey

JWPDUQLIPMJLOF-UHFFFAOYSA-N

LogP

2.058

Topological Polar Surface Area

35.64 Å²

Hydrogen Bond Donor/Acceptor

0 / 4

Complexity

201

Synonyms & References

English

DTXSID30180021
1,4-Di(1H-imidazol-1-yl)benzene
BS-45586
1,1'-(1,4-Phenylene)bis-1H-imidazole
1H-Imidazole, 1,1'-(1,4-phenylene)bis-
YSWG124
D5767
E85564
CHEMBL1923919
1,4-bis(imidazol-1-yl)benzene
CS-0110404
MFCD23103179
25372-07-0
1-[4-(1H-imidazol-1-yl)phenyl]-1H-imidazole
SCHEMBL2532397
1-(4-imidazol-1-ylphenyl)imidazole
AKOS040767953
1H-Imidazole,1,1'-(1,4-phenylene)bis-
1,1'-(1,4-phenylene)bis-1H-Imidazole
1,4-Di-1-imidazolylbenzene
1,4-bis(1-imidazolyl)benzene
bimb

MDL Number

MFCD23103179

FAQ

What are the physical and chemical properties of 1,1'-(1,4-Phenylene)bis(1H-imidazole) (CAS: 25372-07-0)?

1,1'-(1,4-Phenylene)bis(1H-imidazole) is a crystalline solid with a molecular weight of approximately 216.24 g/mol. It has a low solubility in water but is soluble in organic solvents like methanol and dimethylformamide. This compound exhibits good thermal stability and moderate reactivity in various chemical reactions, particularly under basic conditions.

How is 1,1'-(1,4-Phenylene)bis(1H-imidazole) (CAS: 25372-07-0) typically synthesized?

1,1'-(1,4-Phenylene)bis(1H-imidazole) is commonly synthesized via the condensation of 1,4-diaminobenzene with imidazole in the presence of a suitable base such as sodium hydroxide. The reaction yield is typically around 80-90%, and the method is known for its mild conditions and high selectivity.

What industries use 1,1'-(1,4-Phenylene)bis(1H-imidazole) (CAS: 25372-07-0)?

1,1'-(1,4-Phenylene)bis(1H-imidazole) finds applications in the pharmaceutical industry for its use as a building block in drug synthesis, as well as in the polymer industry for developing new materials. It is also used in the sensor and semiconductor industries for its unique electronic properties.

What precautions should be taken when handling 1,1'-(1,4-Phenylene)bis(1H-imidazole) (CAS: 25372-07-0)?

When handling 1,1'-(1,4-Phenylene)bis(1H-imidazole), gloves and goggles should be worn to protect against skin and eye contact. This compound should be handled in a well-ventilated area, preferably in a fume hood, to minimize inhalation risks. In case of spill, it should be carefully cleaned up using appropriate PPE, and the Material Safety Data Sheet (MSDS) should be consulted for detailed instructions.