Orantinib | CAS No. 252916-29-3

Orantinib

Basic Information

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CAS Number

252916-29-3

Molecular Formula

C18H18N2O3

Molecular Weight

310.35 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Basic Physical Properties

Melting Point

239.35° C

Boiling Point

590.5°C at 760 mmHg

Density

1.3300

Refractive Index

1.68

SMILES

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CC1=C(NC(=C1CCC(=O)O)C)C=C2C3=CC=CC=C3NC2=O

InChI

InChI=1S/C18H18N2O3/c1-10-12(7-8-17(21)22)11(2)19-16(10)9-14-13-5-3-4-6-15(13)20-18(14)23/h3-6,9,19H,7-8H2,1-2H3,(H,20,23)(H,21,22)

InChIKey

NHFDRBXTEDBWCZ-UHFFFAOYSA-N

LogP

3.141440000000001

Topological Polar Surface Area

82.19 Å²

Hydrogen Bond Donor/Acceptor

3 / 5

Complexity

516

Safety Information

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Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

J-013813
AC-25028
(Z)-3-(2,4-dimethyl-5-((2-oxoindolin-3-ylidene)methyl)-1H-pyrrol-3-yl)propanoic acid
5-[1,2-Dihydro-2-oxo-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-propanoic acid
TUS-68
SU006668
HY-10517
BRD-K55966568-001-01-3
NSC800809
DB12072
Pdgfr tyrosine kinase inhibitor vi,su6668
CS-0197
NSC 702827
AS-16238
SMR004702878
TSU-68 (SU6668, Orantinib)
NSC702827
5-((1,2-Dihydro-2-oxo-3H-indol-3-ylidene)methyl)-2,4-dimethyl-1H-pyrrole-3-propanoic acid
BCPP000059
NSC-702827
NSC-763929
SU-6668
HMS3413J06
1044712-39-1
HMS3677J06
210644-62-5
BDBM4811
3-(2,4-Dimethyl-5-(2-oxo-1,2-dihydroindol-3-ylidenemethyl)-1H-pyrrol-3-yl)propionic acid
GTPL7816
Q27088210
MLS006011090

MDL Number

MFCD09743433

FAQ

What regulatory guidelines apply to Orantinib (CAS: 252916-29-3)?

Orantinib (CAS: 252916-29-3) falls under regulatory guidelines such as GHS classification, REACH regulations, and requirements set by the FDA and EPA. It is important to comply with specific handling, storage, and disposal guidelines to ensure safety and environmental protection.

Are there alternatives to Orantinib (CAS: 252916-29-3) in synthesis?

In the synthesis of Orantinib (CAS: 252916-29-3), alternatives such as analogous compounds and isomers can be considered. Common alternative reagents include similar inhibitors and related small molecules that may offer similar therapeutic effects or different chemical properties.

What is the market or research trend for Orantinib (CAS: 252916-29-3)?

The market for Orantinib (CAS: 252916-29-3) is growing due to its potential in treating various cancers. Research trends focus on its efficacy, safety, and exploring new applications. Price trends and demand are closely monitored to adapt to market needs and regulatory changes.

How should waste containing Orantinib (CAS: 252916-29-3) be handled?

Waste containing Orantinib (CAS: 252916-29-3) should be collected and disposed of according to hazardous waste regulations. Proper incineration or professional waste disposal methods should be used to minimize environmental impact. Ensure all handling and disposal follow safety guidelines and regulatory requirements to protect the environment and human health.