5-[N-(6-Aminohexyl)-3-(E)-acrylamido]-5’-O-(dimethoxytrityl)-2’-deoxyuridine | CAS No. 252337-60-3

5-[N-(6-Aminohexyl)-3-(E)-acrylamido]-5’-O-(dimethoxytrityl)-2’-deoxyuridine

Basic Information

CAS Number

252337-60-3

Molecular Formula

C39H46N4O8

Molecular Weight

698.8 g/mol

AD

Basic Physical Properties

COC1=CC=C(C=C1)C(C2=CC=CC=C2)(C3=CC=C(C=C3)OC)OCC4C(CC(O4)N5C=C(C(=O)NC5=O)C=CC(=O)NCCCCCCN)O

InChI

InChI=1S/C39H46N4O8/c1-48-31-17-13-29(14-18-31)39(28-10-6-5-7-11-28,30-15-19-32(49-2)20-16-30)50-26-34-33(44)24-36(51-34)43-25-27(37(46)42-38(43)47)12-21-35(45)41-23-9-4-3-8-22-40/h5-7,10-21,25,33-34,36,44H,3-4,8-9,22-24,26,40H2,1-2H3,(H,41,45)(H,42,46,47)

InChIKey

LZRVIYIHUBJELH-UHFFFAOYSA-N

LogP

3.8594000000000013

Topological Polar Surface Area

167.13 Ų

Hydrogen Bond Donor/Acceptor

5 / 12

Synonyms & References

English

  • Uridine, 5-[3-[(6-aminohexyl)amino]-3-oxo-1-propenyl]-5'-O-[bis(4-methoxyphen yl)phenylmethyl]-2'-deoxy-
  • 5-[N-(6-Aminoethyl)-3-E-acrylamido]-2'-deoxy-5'-O-DMT-uridine
  • 5-[N-(6-AMINOHEXYL)-3-E-ACRYLAMIDO]-2'-DEOXY-5'-O-DMT-URIDINE
  • 5’-DMT-5-aha-dU
  • N-(6-aminohexyl)-3-[1-[5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-hydroxyoxolan-2-yl]-2,4-dioxopyrimidin-5-yl]prop-2-enamide
  • Uridine,5-[3-[(6-aminohexyl)amino]-3-oxo-1-propenyl]-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-
  • CTK8E9597

MDL Number

MFCD01631032

FAQ

What is 5-[N-(6-Aminohexyl)-3-(E)-acrylamido]-5’-O-(dimethoxytrityl)-2’-deoxyuridine (CAS: 252337-60-3)?

5-[N-(6-Aminohexyl)-3-(E)-acrylamido]-5’-O-(dimethoxytrityl)-2’-deoxyuridine is a nucleoside derivative with a unique acrylamido group attached to the 3-position of an acrylamide moiety and a dimethoxytrityl group protecting the 5'-OH group. This compound is a key intermediate in the synthesis of certain nucleoside analogs used in pharmaceuticals and research.

What are the main uses of 5-[N-(6-Aminohexyl)-3-(E)-acrylamido]-5’-O-(dimethoxytrityl)-2’-deoxyuridine (CAS: 252337-60-3)?

5-[N-(6-Aminohexyl)-3-(E)-acrylamido]-5’-O-(dimethoxytrityl)-2’-deoxyuridine is primarily used as an intermediate in the synthesis of nucleoside analogs, which are important in the development of antiviral and anticancer drugs. It also finds applications in research for studying nucleic acid chemistry and biology.

Is 5-[N-(6-Aminohexyl)-3-(E)-acrylamido]-5’-O-(dimethoxytrityl)-2’-deoxyuridine (CAS: 252337-60-3) safe?

5-[N-(6-Aminohexyl)-3-(E)-acrylamido]-5’-O-(dimethoxytrityl)-2’-deoxyuridine is generally safe when handled with appropriate laboratory precautions. Users should wear gloves and lab coats, and avoid contact with skin and eyes. It should be stored in a dry, cool place away from light and heat to minimize degradation.

How should 5-[N-(6-Aminohexyl)-3-(E)-acrylamido]-5’-O-(dimethoxytrityl)-2’-deoxyuridine (CAS: 252337-60-3) be stored?

5-[N-(6-Aminohexyl)-3-(E)-acrylamido]-5’-O-(dimethoxytrityl)-2’-deoxyuridine should be stored in a cool, dry place away from direct sunlight and heat sources. It should be kept in a tightly sealed container to prevent degradation. It is important to maintain a stable temperature and avoid exposure to high humidity to preserve its integrity.

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