3,3,3-Trifluoropropanoic acid

Basic Information

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CAS Number

2516-99-6

Molecular Formula

C3H3F3O2

Molecular Weight

128.05 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Fine Chemicals Specialty Chemicals UV Stabilizers

Electronic Chemicals Semiconductor Materials Etchants

Water Treatment Chemicals Coagulants and Flocculants Inorganic Coagulants

Water Treatment Chemicals Disinfectants Chlorine Compounds

Basic Physical Properties

Physical State

Liquid

Melting Point

9.7 °C

Boiling Point

153°C

Refractive Index

n20/D 1.333(lit.)

SMILES

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C(C(=O)O)C(F)(F)F

InChI

InChI=1S/C3H3F3O2/c4-3(5,6)1-2(7)8/h1H2,(H,7,8)

InChIKey

KSNKQSPJFRQSEI-UHFFFAOYSA-N

LogP

1.0234

Topological Polar Surface Area

37.3 Å²

Hydrogen Bond Donor/Acceptor

1 / 2

Complexity

95.2

Safety Information

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Hazard Statement

H226 Flammable liquid and vapor
Flammable liquids

H290 May be corrosive to metals
Corrosive to Metals

H314 Causes severe skin burns and eye damage
Skin corrosion/irritation

Hazard Class

Class 8 Class 8

Synonyms & References

English

FT-0613979
3,3,3-tri-fluoropropionic acid
CHEMBL448844
3,3,3-trifluoro propanoic acid
trifluoromethylacetic acid
3,3,3-Trifluoropropionic acid, 98%
C3H3F3O2
DTXSID70380740
3,3,3,-trifluoropropionic acid
3,3,3-Trifluoropropionic acid
AMY6809
2516-99-6
BP-13309
F0001-0847
PROPANOIC ACID, 3,3,3-TRIFLUORO-
3,3,3-trifluoropropanoicacid
AB04100
EN300-26707
J-511050
SCHEMBL185832
3,3,3-trifluoropropanoic acid
CS-0051640
AKOS000200428
MFCD00153292
FT-PFCA; C3H3F3O2
SIBLLOQSMPMYAX-UHFFFAOYSA-N
1:2 fluorotelomer carboxylic acid
T1713
1:2 fluorotelomer acid
3,3,3-trifluoro-propionic acid
AS-38506

MDL Number

MFCD00153292

Customs Code

2915900090

FAQ

What are the physical and chemical properties of 3,3,3-Trifluoropropanoic acid (CAS: 2516-99-6)?

3,3,3-Trifluoropropanoic acid is a colorless, crystalline solid with a molecular weight of 146.03 g/mol. It has a high melting point at 113-114°C and is slightly soluble in water. Chemically, it is a carboxylic acid with strong acidic properties, showing reactivity towards bases and nucleophiles. It is used in organic synthesis and as a component in various chemical processes due to its unique trifluoromethyl group.

How is 3,3,3-Trifluoropropanoic acid (CAS: 2516-99-6) typically synthesized?

3,3,3-Trifluoropropanoic acid can be synthesized through the hydrolysis of fluoropropanes, typically using strong acids as catalysts. The reaction involves the conversion of trifluoromethyl halides to the corresponding carboxylic acid, which can then be isolated and purified. This process often requires controlled conditions to ensure high selectivity and yield.

What industries use 3,3,3-Trifluoropropanoic acid (CAS: 2516-99-6)?

3,3,3-Trifluoropropanoic acid is used in various industries, including pharmaceuticals for the synthesis of drug intermediates, polymers as a monomer, and in the production of sensors and semiconductors due to its unique trifluoromethyl functional group. It is also utilized in organic synthesis and as a reagent in academic and industrial research.

What precautions should be taken when handling 3,3,3-Trifluoropropanoic acid (CAS: 2516-99-6)?

When handling 3,3,3-Trifluoropropanoic acid, it is essential to use appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a fume hood to minimize exposure. Spills should be handled with care, using appropriate cleanup materials, and the area should be well-ventilated. Always consult the Safety Data Sheet (SDS) for detailed safety information and emergency procedures.