(16beta)-21-Chloro-9-fluoro-16-methyl-3,11,20-trioxopregna-1,4-dien-17-yl butyrate | CAS No. 25122-57-0

(16beta)-21-Chloro-9-fluoro-16-methyl-3,11,20-trioxopregna-1,4-dien-17-yl butyrate

Basic Information

CAS Number

25122-57-0

Molecular Formula

C26H32ClFO5

Molecular Weight

478.99 g/mol

AD

Basic Physical Properties

Melting Point

177.0 to 181.0 deg-C

CCCC(=O)OC1(C(CC2C1(CC(=O)C3(C2CCC4=CC(=O)C=CC43C)F)C)C)C(=O)CCl

InChI

InChI=1S/C26H32ClFO5/c1-5-6-22(32)33-26(21(31)14-27)15(2)11-19-18-8-7-16-12-17(29)9-10-23(16,3)25(18,28)20(30)13-24(19,26)4/h9-10,12,15,18-19H,5-8,11,13-14H2,1-4H3/t15-,18-,19-,23-,24-,25-,26-/m0/s1

InChIKey

FBRAWBYQGRLCEK-AVVSTMBFSA-N

LogP

4.701400000000005

Topological Polar Surface Area

77.51 Ų

Hydrogen Bond Donor/Acceptor

0 / 5

Complexity

987

Safety Information

View Safety Information

GHS Hazard Pictograms

H361H361

Hazard Statement

H361 Suspected of damaging fertility or the unborn child
Reproductive toxicity

Stability

Stable. Combustible. Incompatible with strong oxidizing agents.

Synonyms & References

English

  • Kindavate (TN)
  • Q27271005
  • SR-01000000249-3
  • CLOBETASONE BUTYRATE [JAN]
  • Pregna-1,4-diene-3,11,20-trione, 21-chloro-9-fluoro-16-methyl-17-(1-oxobutoxy)-, (16.beta.)-
  • 8U0H6XI6EO
  • AS-14689
  • Pregna-1,4-diene-3,11,20-trione, 21-chloro-9-fluoro-16-methyl-17-(1-oxobutoxy)-, (16b)-
  • (16beta)-21-Chloro-9-fluoro-16-methyl-3,11,20-trioxopregna-1,4-dien-17-yl butyrate
  • Molivate
  • D01273
  • GR 2/1214
  • DTXCID1026823
  • Clobetasone 17-butyrate
  • NCGC00022019-03
  • W-107264
  • DTXSID3046823
  • Clobetasone butyrate for system suitability, European Pharmacopoeia (EP) Reference Standard
  • MLS001076290
  • Clobetasone butyrate (JAN/USAN)
  • MFCD00133196
  • NS00015388
  • HMS2234B13
  • GR-2/1214
  • CHEMBL577673
  • GNF-Pf-1500
  • 21-Chloro-9-fluoro-17-hydroxy-16-beta-methylpregna-1,4-diene,3,11,20-trione butyrate
  • Kindavate
  • Tox21_112691
  • CS-0013549
  • MLS000028658

MDL Number

MFCD00133196

Customs Code

29372290

FAQ

What regulatory guidelines apply to (16beta)-21-Chloro-9-fluoro-16-methyl-3,11,20-trioxopregna-1,4-dien-17-yl butyrate (CAS: 25122-57-0)?

This compound falls under the European Union's REACH regulations for chemical safety and is subject to GHS (Globally Harmonized System of Classification and Labeling of Chemicals) classification. It is also regulated by the EPA and FDA in the United States for environmental and health safety. Proper handling, storage, and disposal must comply with local and international laws.

Are there alternatives to (16beta)-21-Chloro-9-fluoro-16-methyl-3,11,20-trioxopregna-1,4-dien-17-yl butyrate (CAS: 25122-57-0) in synthesis?

Alternative reagents such as (16beta)-21-methoxy-9-fluoro-16-methyl-3,11,20-trioxopregna-1,4-dien-17-yl butyrate and (16beta)-21-hydroxy-9-fluoro-16-methyl-3,11,20-trioxopregna-1,4-dien-17-yl butyrate are explored in synthesis. Isomers and analogs like (16alpha)-21-chloro-9-fluoro-16-methyl-3,11,20-trioxopregna-1,4-dien-17-yl butyrate can serve as viable alternatives.

What is the market or research trend for (16beta)-21-Chloro-9-fluoro-16-methyl-3,11,20-trioxopregna-1,4-dien-17-yl butyrate (CAS: 25122-57-0)?

Research is focused on its applications in pharmaceuticals and agriculture, with increasing interest in its synthetic routes and potential in novel drug discovery. Market trends indicate growing demand in the pharmaceutical industry, particularly for its use as an intermediate in bioactive compound synthesis.

How should waste containing (16beta)-21-Chloro-9-fluoro-16-methyl-3,11,20-trioxopregna-1,4-dien-17-yl butyrate (CAS: 25122-57-0) be handled?

Waste containing this compound should be collected in sealed containers and disposed of through a licensed waste disposal company. Incineration is a common method, but environmental protection precautions must be taken to prevent contamination. Compliance with local regulations is essential for safe disposal.

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