(11beta,16beta)-21-Chloro-9-fluoro-11-hydroxy-16-methyl-3,20-dioxopregna-1,4-dien-17-yl propionate | CAS No. 25122-46-7

(11beta,16beta)-21-Chloro-9-fluoro-11-hydroxy-16-methyl-3,20-dioxopregna-1,4-dien-17-yl propionate

Basic Information

CAS Number

25122-46-7

Molecular Formula

C25H32ClFO5

Molecular Weight

466.98 g/mol

AD

Basic Physical Properties

Melting Point

196.0 to 200.0 deg-C

Boiling Point

569°C at 760 mmHg

Flash Point

297.9 oC

Refractive Index

1.56

Specific Rotation

+99 - +103° (c=1, Dioxane)

CCC(=O)O[C@@]1([C@@H](C)C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@@]21C)C(=O)CCl

InChI

InChI=1S/C25H32ClFO5/c1-5-21(31)32-25(20(30)13-26)14(2)10-18-17-7-6-15-11-16(28)8-9-22(15,3)24(17,27)19(29)12-23(18,25)4/h8-9,11,14,17-19,29H,5-7,10,12-13H2,1-4H3/t14-,17-,18-,19-,22-,23-,24-,25-/m0/s1

InChIKey

CBGUOGMQLZIXBE-XGQKBEPLSA-N

LogP

4.103100000000004

Topological Polar Surface Area

80.67000000000002 Ų

Hydrogen Bond Donor/Acceptor

1 / 5

Complexity

929

Safety Information

View Safety Information

GHS Hazard Pictograms

H373H373
H413

Hazard Statement

H373 Causes damage to organs through prolonged or repeated exposure
Specific target organ toxicity, repeated exposure
H413 May cause long lasting harmful effects to aquatic life
Hazardous to the aquatic environment, long-term hazard

Synonyms & References

English

  • clobetasol propionate
  • 17-propionate
  • cgp9555
  • clobesol
  • pregna-1,4-diene-3,20-dione,21-chloro-9-fluoro-11-beta,17-dihydroxy-16-beta-me
  • CLOBESTASOL PROPIONATE
  • CLOBETASOL-17-PROPIONATE
  • Clobetasol 17-Propionate
  • Clobetasol for peak identification
  • CLOBETASOL PROPIONATE, USP
  • 21-Chloro-9α-fluoro-11β,17α-dihydroxy-16β-methyl-1,4-pregnadiene-3,20-dione 17-Propionate
  • 925
  • CCl 4725
  • Cloβsol 17-Propionate
  • Dermoval
  • Dermovate
  • GR 2
  • GR-2
  • Olux
  • Psorex
  • Temovate
  • 21-Chloro-9-fluoro-11b,17-dihydroxy-16b-methylpregna-1,4-diene-3,20-dione 17-propionate
  • Clobex
  • Embeline
  • Embeline E
  • Cormax
  • Temovate E
  • Olux-E
  • clobetasol 17-propanoate
  • GR 2/925
  • C25H32ClFO5

MDL Number

MFCD00058499

Customs Code

2937290090

FAQ

What is (11beta,16beta)-21-Chloro-9-fluoro-11-hydroxy-16-methyl-3,20-dioxopregna-1,4-dien-17-yl propionate (CAS: 25122-46-7)?

This compound is a derivative of corticosteroids, specifically a 17-beta-hydroxyprogesterone analog. Its chemical structure includes a chloro, fluoro, and methyl group, along with a propionate side chain. It is known for its potent anti-inflammatory and immunosuppressive properties. As a synthetic compound, it is often used in research and pharmaceutical development for its potential therapeutic applications. The CAS number 25122-46-7 uniquely identifies this specific molecular form.

What are the main uses of (11beta,16beta)-21-Chloro-9-fluoro-11-hydroxy-16-methyl-3,20-dioxopregna-1,4-dien-17-yl propionate (CAS: 25122-46-7)?

This compound is primarily used in pharmaceutical research for its anti-inflammatory and immunosuppressive effects. It may also find applications in the development of topical treatments for skin conditions. Its use in industry is limited, but it serves as a valuable tool in drug discovery. The CAS number 25122-46-7 ensures accurate identification and reference in scientific literature.

Is (11beta,16beta)-21-Chloro-9-fluoro-11-hydroxy-16-methyl-3,20-dioxopregna-1,4-dien-17-yl propionate (CAS: 25122-46-7) safe?

Safety of this compound depends on its application and dosage. It is generally considered safe in controlled research settings but may have potential health risks if misused. Proper handling and protective measures are essential when working with it. Safety standards for chemical handling should be followed to ensure minimal exposure. The CAS number 25122-46-7 is important for tracking and regulating its use.

How should (11beta,16beta)-21-Chloro-9-fluoro-11-hydroxy-16-methyl-3,20-dioxopregna-1,4-dien-17-yl propionate (CAS: 25122-46-7) be stored?

This compound should be stored in a cool, dry, and dark place to maintain its stability. It is recommended to keep it in a sealed container away from moisture and light. Storage at temperatures below 25°C is ideal to prevent degradation. Proper labeling is essential for safe handling. The CAS number 25122-46-7 should be noted for accurate reference during storage and transportation.

Related Compounds

You might also like

Compound Q&A

What is 6-Methyl-7-oxabicyclo[4.1.0]heptan-2-one (CAS: 21889-89-4)?

6-Methyl-7-oxabicyclo[4.1.0]heptan-2-one is a cyclic ketone with a molecular for...

21889-89-46-Methyl-7-oxabicycl...
Compound Q&A

What is 4-[(6-Methyl-2-pyrazinyl)oxy]benzoic acid (CAS: 906353-00-2)?

4-[(6-Methyl-2-pyrazinyl)oxy]benzoic acid is a chemical compound with the CAS nu...

906353-00-24-[(6-Methyl-2-pyraz...
Compound Q&A

What is 2-(2-Pyridinyl)-1,3-propanediol (CAS: 49745-42-8)?

2-(2-Pyridinyl)-1,3-propanediol (CAS: 49745-42-8) is a colorless to slightly yel...

49745-42-82-(2-Pyridinyl)-1,3-...
Compound Q&A

What is 2-(6-Chloro-2-pyridinyl)-2-phenylacetonitrile (CAS: 24783-42-4)?

2-(6-Chloro-2-pyridinyl)-2-phenylacetonitrile is an organic compound with the CA...

24783-42-42-(6-Chloro-2-pyridi...
Compound Q&A

What is 2-Oxopropanamide (CAS: 631-66-3)?

2-Oxopropanamide, also known as 2-aminoacrylic acid, is a chemical compound with...

631-66-32-Oxopropanamide
Compound Q&A

What is 2-Methyl-2-propanyl 4-(5-bromo-6-methyl-2-pyridinyl)-1-piperazinecarboxylate (CAS: 1289040-88-5)?

2-Methyl-2-propanyl 4-(5-bromo-6-methyl-2-pyridinyl)-1-piperazinecarboxylate (CA...

1289040-88-52-Methyl-2-propanyl ...
Compound Q&A

What is NAMPT inhibitor-linker 1 (CAS: 2241019-57-6)?

NAMPT inhibitor-linker 1 (CAS: 2241019-57-6) is a chemical compound designed as ...

2241019-57-6NAMPT inhibitor-link...
Compound Q&A

What is (2-(2,2,2-Trifluoroacetyl)pyridin-4-yl)boronic acid (CAS: 1310404-58-0)?

It is a chemical compound with the structure (2-(2,2,2-Trifluoroacetyl)pyridin-4...

1310404-58-0(2-(2,2,2-Trifluoroa...
Compound Q&A

What is 1-(2-Chlorophenyl)-6-(3,3,3-trifluoro-2-methylpropyl)-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one (CAS: 794568-90-4)?

1-(2-Chlorophenyl)-6-(3,3,3-trifluoro-2-methylpropyl)-1,5-dihydro-4H-pyrazolo[3,...

794568-90-41-(2-Chlorophenyl)-6...
Compound Q&A

What is Vinyl(chloromethyl)dimethoxysilane (CAS: 1314981-48-0)?

Vinyl(chloromethyl)dimethoxysilane is an organosilicon compound with the molecul...

1314981-48-0Vinyl(chloromethyl)d...