Copovidone (Technical Grade)

Basic Information

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CAS Number

25086-89-9

Molecular Formula

C10H15NO3

Molecular Weight

197.23 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Esters

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

Boiling Point

536.7±50.0 °C at 760 mmHg

Refractive Index

1.4300 to 1.4380

SMILES

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CC(=O)OC=C.C=CN1CCCC1=O

InChI

InChI=1S/C6H9NO.C4H6O2/c1-2-7-5-3-4-6(7)8;1-3-6-4(2)5/h2H,1,3-5H2;3H,1H2,2H3

InChIKey

FYUWIEKAVLOHSE-UHFFFAOYSA-N

LogP

1.4453

Topological Polar Surface Area

46.61 Å²

Hydrogen Bond Donor/Acceptor

0 / 4

Complexity

186

Safety Information

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GHS Hazard Pictograms

H225

Hazard Statement

H225 Highly Flammable liquid and vapor
Flammable liquids

Hazard Class

Class 3 Class 3

Stability

Stable. Combustible, especially in powdered form. Incompatible with strong oxidising agents, strong reducing agents.

Sensitiveness

photosensitive

Synonyms & References

English

N-vinylpyrrolidone/vinyl acetate
FT-0659810
GAF-S 630
BCP31918
NSC114026
ethenyl acetate;1-ethenylpyrrolidin-2-one
Ganex E 535
Luviskol VA-64
Kolima 10
vinylpyrrolidone/vinyl acetate
Copovidone (Technical Grade)
SCHEMBL29127
NSC-114025
Luviskol VA 64
AKOS015898247
Luviskol VA 28I
Polectron 845
PVP-VA
I 535
NSC114025
733045-73-3
I 635
NSC-114023
25086-89-9
I 735
Kolima 35
MFCD00134018
NSC-114026
Luviskol VA 37E
Gantron S 860
1-ethenylpyrrolidin-2-one; ethenyl acetate

MDL Number

MFCD00134018

FAQ

What is Copovidone (CAS: 25086-89-9)?

Copovidone (CAS: 25086-89-9) is a water-soluble polymer derived from cyclodextrin, commonly used in pharmaceutical and cosmetic formulations. Its chemical formula is C14H20O6, and it exhibits excellent binding, film-forming, and disintegrating properties. Copovidone is known for its ability to enhance drug solubility and stability, making it a versatile excipient in tablet manufacturing and controlled-release systems.

What are the main uses of Copovidone (CAS: 25086-89-9)?

Copovidone (CAS: 25086-89-9) is primarily used as a binder and disintegrant in pharmaceutical tablets, improving tablet integrity and dissolution rates. It also serves as a film-forming agent in coatings and is applied in cosmetic products for texture enhancement. Additionally, it finds use in food industry applications as a stabilizer and in research for drug delivery system development.

Is Copovidone (CAS: 25086-89-9) safe?

Copovidone (CAS: 25086-89-9) is generally considered safe when handled according to standard safety protocols. It has low toxicity and minimal skin or eye irritation potential. However, proper protective equipment such as gloves and safety goggles is recommended during handling. Safety standards ensure its compliance with regulatory guidelines for pharmaceutical and industrial use.

How should Copovidone (CAS: 25086-89-9) be stored?

Copovidone (CAS: 25086-89-9) should be stored in a cool, dry, and dark environment to maintain stability. It is best kept in a sealed, airtight container to prevent moisture exposure. Storage temperatures should remain below 25°C, and humidity levels should be controlled to avoid degradation. Proper storage ensures optimal shelf life and performance in formulations.