Varenicline | CAS No. 249296-44-4

Varenicline

Basic Information

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CAS Number

249296-44-4

Molecular Formula

C13H13N3

Molecular Weight

211.27 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

SMILES

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C1C2CNCC1C3=CC4=NC=CN=C4C=C23

InChI

InChI=1S/C13H13N3/c1-2-16-13-5-11-9-3-8(6-14-7-9)10(11)4-12(13)15-1/h1-2,4-5,8-9,14H,3,6-7H2/t8-,9+

InChIKey

JQSHBVHOMNKWFT-DTORHVGOSA-N

LogP

1.8038999999999998

Topological Polar Surface Area

37.81 Å²

Hydrogen Bond Donor/Acceptor

1 / 3

Complexity

254

Synonyms & References

English

NS00000682
249296-44-4
CHEMBL1396
7,8,9,10-tetrahydro- 6,10-methano- 6H-pyrazino (2,3-h)(3) benzazepine
(6R,10S)-7,8,9,10-tetrahydro-6H-6,10-methanoazepino[4,5-g]quinoxaline
5,8,14-Triazatetracyclo[10.3.1.02, 11.04,9]hexadeca-2(11),3,5,7,9-pentaene
NCGC00247735-01
CHEMBL556954
7,8,9,10-Tetrahydro-6,10-methano-6H-pyrazino[2,3-h][3]benzazepine(Varenicline)
6,7,8,9-tetrahydro-6,10-methano-6H-pyrazino(2,3-h)benzazepine
NCGC00247735-03
5,8,14-triazatetracyclo[10.3.1.02,11.04,9]hexadeca-2(11),3,5,7,9-pentaene
5,8,14-triazatetracyclo[10.3.1.02,11.04,9]hexadeca-2,4,6,8,10-pentaene
5,8,14-triazatetracyclo[10.3.1.02,11.04,9]-hexadeca-2(11),3,5,7,9-pentaene
Varenicline
J-501695
6,10-Methano-6H-pyrazino[2,3-h][3]benzazepine, 7,8,9,10-tetrahydro-
BDBM50166908
Varenicline (INN)
CP-526555
5,8,14-triazatetracyclo[10.3.1.0^{2,11}.0^{4,9}]hexadeca-2(11),3,5,7,9-pentaene
CP 526555; Champix; Chantix
CS-0396
A849621
MS-23161
5,8,14-triazatetracyclo[10.3.1.02,11.04,9]-hexadeca-2(11),3,5,7,9pentaene
NCGC00247735-02
AKOS005145561
SB17430
7,8,9,10-Tetrahydro-6,10-methano-6H-pyrazino-[2,3-h][3]benzazepine
BCP01413

MDL Number

MFCD10001497

FAQ

What regulatory guidelines apply to Varenicline (CAS: 249296-44-4)?

Varenicline (CAS: 249296-44-4) is regulated by the Globally Harmonized System (GHS) for classification and labeling of chemicals. In the European Union, it is governed by the Registration, Evaluation, Authorization, and Restriction of Chemicals (REACH) regulation. The U.S. Food and Drug Administration (FDA) and Environmental Protection Agency (EPA) have specific requirements for its use and handling, ensuring safety and environmental protection.

Are there alternatives to Varenicline (CAS: 249296-44-4) in synthesis?

In the synthesis of Varenicline (CAS: 249296-44-4), alternative reagents and methods such as nicotine derivatives and other psychotropic agents can be considered. For instance, bupropion and other nicotinic acid agonists are sometimes used as substitutes depending on the desired outcome and availability of reagents.

What is the market or research trend for Varenicline (CAS: 249296-44-4)?

Varenicline (CAS: 249296-44-4) has been increasingly studied for its applications in smoking cessation. Market trends indicate a steady demand for this medication, supported by ongoing research into its efficacy and potential for treating other conditions. The trend suggests that advancements in pharmaceutical research will continue to drive interest in Varenicline and similar compounds.

How should waste containing Varenicline (CAS: 249296-44-4) be handled?

Waste containing Varenicline (CAS: 249296-44-4) should be handled according to local and international regulations. It is recommended to collect waste in appropriate containers and dispose of it through a professional waste disposal service. Environmental protection precautions include proper labeling and storage to prevent contamination of soil and water. Always consult local regulations and safety guidelines for detailed disposal procedures.