2-{[(2-Ethylhexyl)oxy]methyl}oxirane | CAS No. 2461-15-6

Q: What are the physical and chemical properties of 2-{[(2-Ethylhexyl)oxy]methyl}oxirane (CAS: 2461-15-6)?

2-{[(2-Ethylhexyl)oxy]methyl}oxirane (CAS: 2461-15-6) has a crystalline form at room temperature. Its molecular weight is approximately 216.33 g/mol. It has low solubility in water but is soluble in common organic solvents like ethanol and acetone. This compound is reactive and can undergo ring-opening reactions under basic conditions. It is often used in polymer chemistry and pharmaceutical applications due to its unique reactivity.

Q: How is 2-{[(2-Ethylhexyl)oxy]methyl}oxirane (CAS: 2461-15-6) typically synthesized?

2-{[(2-Ethylhexyl)oxy]methyl}oxirane (CAS: 2461-15-6) is typically synthesized through oxyamination of 2-iodo-2-methyl-1-oxirane with 2-ethylhexylamine. Commonly, this reaction is catalyzed by a transition metal complex. The process yields a mixture of diastereomers, with good selectivity and high yield. This method is widely used in industrial settings for the production of this compound.

Q: What industries use 2-{[(2-Ethylhexyl)oxy]methyl}oxirane (CAS: 2461-15-6)?

2-{[(2-Ethylhexyl)oxy]methyl}oxirane (CAS: 2461-15-6) is primarily used in the pharmaceutical and polymer industries. It serves as a key intermediate in the synthesis of various drugs and is also used in the production of polyurethane coatings and adhesives. Its unique chemical properties make it valuable in developing new materials and pharmaceuticals.

Q: What precautions should be taken when handling 2-{[(2-Ethylhexyl)oxy]methyl}oxirane (CAS: 2461-15-6)?

When handling 2-{[(2-Ethylhexyl)oxy]methyl}oxirane (CAS: 2461-15-6), it is essential to use appropriate personal protective equipment (PPE), including gloves and safety goggles. Work should be conducted in a well-ventilated area or a fume hood. Spills should be carefully cleaned up using appropriate chemicals. Always refer to the Safety Data Sheet (SDS) for detailed handling and emergency procedures. This compound is reactive and can be irritating to the eyes and skin.

2-{[(2-Ethylhexyl)oxy]methyl}oxirane

Basic Information

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CAS Number

2461-15-6

Molecular Formula

C11H22O2

Molecular Weight

186.29 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

Boiling Point

61°C/0.3mmHg

Water Solubility

<0.1 g/100 mL at 19 ºC

Refractive Index

n20/D 1.434(lit.)

SMILES

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CCCCC(CC)COCC1CO1

InChI

InChI=1S/C11H22O2/c1-3-5-6-10(4-2)7-12-8-11-9-13-11/h10-11H,3-9H2,1-2H3

InChIKey

BBBUAWSVILPJLL-UHFFFAOYSA-N

LogP

2.6182000000000007

Topological Polar Surface Area

21.759999999999998 Å²

Hydrogen Bond Donor/Acceptor

0 / 2

Complexity

125

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H402 Harmful to aquatic life
Hazardous to the aquatic environment, acute hazard

Stability

Stable. Combustible. Incompatible with strong oxidising agents, acids, bases.

Synonyms & References

English

2-Ethylhexyl glycidyl ether
1,2-Epoxy-3-((2-ethylhexyl)oxy)propane
2-[[(2-Ethylhexyl)oxy]methyl]oxirane-d5
(((2-ethylhexyl)oxy)methyl)oxirane
(2-Ethylhexyloxy)-2,3-epoxypropane
(2-ethylhexyloxy)oxyran-2-ylmethane
[(2-Ethylhexyl)methyl]oxirane
2-(2-Ethylhexoxymethyl)oxirane
2-ethvlhexvlglvcidvlether
2-ethylhexyl glycidal ether
2-ethyl-hexyl glycidyl ether
3-(Glycidyloxymethyl)heptane
EHGE
glycidyl2-ethylhexylether

MDL Number

MFCD00005141

FAQ

What are the physical and chemical properties of 2-{[(2-Ethylhexyl)oxy]methyl}oxirane (CAS: 2461-15-6)?

2-{[(2-Ethylhexyl)oxy]methyl}oxirane (CAS: 2461-15-6) has a crystalline form at room temperature. Its molecular weight is approximately 216.33 g/mol. It has low solubility in water but is soluble in common organic solvents like ethanol and acetone. This compound is reactive and can undergo ring-opening reactions under basic conditions. It is often used in polymer chemistry and pharmaceutical applications due to its unique reactivity.

How is 2-{[(2-Ethylhexyl)oxy]methyl}oxirane (CAS: 2461-15-6) typically synthesized?

2-{[(2-Ethylhexyl)oxy]methyl}oxirane (CAS: 2461-15-6) is typically synthesized through oxyamination of 2-iodo-2-methyl-1-oxirane with 2-ethylhexylamine. Commonly, this reaction is catalyzed by a transition metal complex. The process yields a mixture of diastereomers, with good selectivity and high yield. This method is widely used in industrial settings for the production of this compound.

What industries use 2-{[(2-Ethylhexyl)oxy]methyl}oxirane (CAS: 2461-15-6)?

2-{[(2-Ethylhexyl)oxy]methyl}oxirane (CAS: 2461-15-6) is primarily used in the pharmaceutical and polymer industries. It serves as a key intermediate in the synthesis of various drugs and is also used in the production of polyurethane coatings and adhesives. Its unique chemical properties make it valuable in developing new materials and pharmaceuticals.

What precautions should be taken when handling 2-{[(2-Ethylhexyl)oxy]methyl}oxirane (CAS: 2461-15-6)?

When handling 2-{[(2-Ethylhexyl)oxy]methyl}oxirane (CAS: 2461-15-6), it is essential to use appropriate personal protective equipment (PPE), including gloves and safety goggles. Work should be conducted in a well-ventilated area or a fume hood. Spills should be carefully cleaned up using appropriate chemicals. Always refer to the Safety Data Sheet (SDS) for detailed handling and emergency procedures. This compound is reactive and can be irritating to the eyes and skin.