(4S)-5-[(2-Methyl-2-propanyl)oxy]-4-({[(2-methyl-2-propanyl)oxy]carbonyl}amino)-5-oxopentanoic acid

Basic Information

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CAS Number

24277-39-2

Molecular Formula

C14H25NO6

Molecular Weight

303.36 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Esters

Basic Chemical Raw Materials Organic Chemicals Ethers

Fine Chemicals Surfactants Anionic Surfactants

Basic Physical Properties

Melting Point

111.0 to 115.0 deg-C

Boiling Point

449.8°Cat760mmHg

Density

1.1210

Flash Point

225.8°C

Solubility

Soluble in dimethyl formamide.

Refractive Index

1.47

Specific Rotation

-27° - -33° (c=1, MeOH)

SMILES

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CC(C)(C)OC(=O)C(CCC(=O)O)NC(=O)OC(C)(C)C

InChI

InChI=1S/C14H25NO6/c1-13(2,3)20-11(18)9(7-8-10(16)17)15-12(19)21-14(4,5)6/h9H,7-8H2,1-6H3,(H,15,19)(H,16,17)/t9-/m0/s1

InChIKey

YMOYURYWGUWMFM-VIFPVBQESA-N

LogP

2.0862

Topological Polar Surface Area

101.92999999999999 Å²

Hydrogen Bond Donor/Acceptor

2 / 7

Complexity

391

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Sensitiveness

thermally sensitive

Synonyms & References

English

1-tert-Butyl N-Boc-L-glutamate
Q-101543
N-(t-butoxycarbonyl)-L-glutamic acid t-butyl ester
(S)-5-tert-butoxy-4-(tert-butoxycarbonylamino)-5-oxopentanoic acid
t-Boc-Glu-OtBu
N-Boc-L-glutamic acid 1-tert-butyl ester
tert-butoxycarbonyl-L-glutamic acid 1-tert-butyl ester
N-tert.butyloxycarbonyl-L-glutamic acid 1-tert.-butyl ester
FD21387
N-(tert-Butoxycarbonyl)-L-glutamic Acid 1-tert-Butyl Ester
Boc-L-glutamic acid 1-tert-butyl ester
SCHEMBL863894
HY-W007354
A26756
AKOS015924134
EN300-761531
DS-15097
J-300111
MFCD00038273
24277-39-2
(4S)-4-((tert-butyl)oxycarbonyl)-4-((tert-butoxy)carbonylamino)butanoic acid
N-boc-l-glutamic acid 1-t-butyl ester
N-BOC-glutamic acid tert-butyl ester
YMOYURYWGUWMFM-VIFPVBQESA-N
(4S)-5-(tert-butoxy)-4-[[(tert-butoxy)carbonyl]amino]-5-oxopentanoic acid
N-alpha-t-Butyloxycarbonyl-L-glutamic acid-alpha-t-butyl ester
DTXSID50426357
N-Boc-L-glutamic Acid tert-Butyl Ester
Boc-L-glutamic acid a-tert-butyl ester
(S)-2-tert-Butoxycarbonylamino-pentanedioic acid 1-tert-butyl ester
1-tert-Butyl N-(tert-Butoxycarbonyl)-L-glutamate

MDL Number

MFCD00038273

FAQ

What is (4S)-5-[(2-Methyl-2-propanyl)oxy]-4-({[(2-methyl-2-propanyl)oxy]carbonyl}amino)-5-oxopentanoic acid (CAS: 24277-39-2)?

This compound is a chiral pentanoic acid derivative with the molecular formula C10H20O5N. It features a complex structure including two tert-butyl groups, an amino group, and a carbonyl group, making it a valuable intermediate in organic synthesis. The (4S,5S) stereoconfiguration indicates its potential role in enantiomer-specific applications, such as pharmaceuticals and biochemistry research.

What are the main uses of (4S)-5-[(2-Methyl-2-propanyl)oxy]-4-({[(2-methyl-2-propanyl)oxy]carbonyl}amino)-5-oxopentanoic acid (CAS: 24277-39-2)?

This compound is primarily used in pharmaceutical research as a building block for drug development, particularly in the synthesis of chiral molecules. It also serves in organic chemistry as a functional group modifier and in academic studies for exploring stereochemical effects. Its unique structure makes it relevant for applications requiring precise stereocontrol, such as enzyme inhibitors or targeted therapies.

Is (4S)-5-[(2-Methyl-2-propanyl)oxy]-4-({[(2-methyl-2-propanyl)oxy]carbonyl}amino)-5-oxopentanoic acid (CAS: 24277-39-2) safe?

Safety data for this compound is limited, but as a chemical intermediate, it requires standard lab precautions. It may pose risks through inhalation or skin contact, so use of gloves, goggles, and a fume hood is recommended. Always follow OSHA guidelines and consult the Safety Data Sheet (SDS) for specific handling instructions. Proper ventilation and protective measures are essential during manipulation.

How should (4S)-5-[(2-Methyl-2-propanyl)oxy]-4-({[(2-methyl-2-propanyl)oxy]carbonyl}amino)-5-oxopentanoic acid (CAS: 24277-39-2) be stored?

Store in a sealed, airtight container in a cool, dry place, away from direct light and moisture. Maintain storage temperature below 25°C and ensure humidity levels are low to prevent degradation. Use glass or high-density polyethylene containers to avoid chemical interactions. Always keep it in a well-ventilated area and follow manufacturer guidelines for long-term stability.