Ethyl 1-methyl-4-piperidinecarboxylate

Basic Information

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CAS Number

24252-37-7

Molecular Formula

C9H17NO2

Molecular Weight

171.24 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Esters

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

Physical State

No data available

Melting Point

No data available

Boiling Point

211°C at 760 mmHg

Refractive Index

n20/D 1.450

SMILES

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CCOC(=O)C1CCN(CC1)C

InChI

InChI=1S/C9H17NO2/c1-3-12-9(11)8-4-6-10(2)7-5-8/h8H,3-7H2,1-2H3

InChIKey

JWXOOQCMGJBSML-UHFFFAOYSA-N

LogP

0.8913

Topological Polar Surface Area

29.54 Å²

Hydrogen Bond Donor/Acceptor

0 / 3

Complexity

151

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H318 Causes serious eye damage
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

F2167-0073
AM20090267
SY009066
EN300-1265681
AC-22456
Ethyl 1-methyl-4-piperidinecarboxylate
DS-13280
MFCD00130015
ethyl 1-methyl-piperidine-4-carboxylate
JWXOOQCMGJBSML-UHFFFAOYSA-N
24252-37-7
Ethyl 1-methylpiperidine-4-carboxylate
1-methyl-4-piperdine carboxylic acid ethyl ester
CS-0030553
1-methylpiperidine-4-carboxylic acid ethyl ester
1-methyl-4-piperidinecarboxylic acid ethyl ester
FT-0645161
AB03667
Ethyl 1-methylpiperidine-4-carboxylate, 97%
DTXSID80453777
AKOS005259755
SCHEMBL446501
1-Methyl-piperidine-4-carboxylic acid ethyl ester
Ethyl1-methylpiperidine-4-carboxylate
W-206881
4-Piperidinecarboxylic acid, 1-methyl-, ethyl ester
Ethyl 1-methyl Piperidine-4-carboxylate
A817170
SCHEMBL12935486
ETHYL N-METHYLISONIPECOTATE
Ethyl N-methyl piperidine-4-carboxylate

MDL Number

MFCD00130015

Customs Code

2933399090

FAQ

What are the physical and chemical properties of Ethyl 1-methyl-4-piperidinecarboxylate (CAS: 24252-37-7)?

Ethyl 1-methyl-4-piperidinecarboxylate (CAS: 24252-37-7) is a white crystalline solid with a molecular weight of approximately 191.25 g/mol. It is slightly soluble in water but more soluble in organic solvents like ethanol and acetone. The compound is moderately reactive, particularly towards nucleophiles and bases, and it can undergo ester hydrolysis under basic conditions.

How is Ethyl 1-methyl-4-piperidinecarboxylate (CAS: 24252-37-7) typically synthesized?

Ethyl 1-methyl-4-piperidinecarboxylate (CAS: 24252-37-7) is typically synthesized via the condensation of 1-methyl-4-piperidinecarboxylic acid with ethylamine in the presence of a base like sodium triacetoxyborohydride. The reaction provides good selectivity and yield, making it a common method in organic synthesis.

What industries use Ethyl 1-methyl-4-piperidinecarboxylate (CAS: 24252-37-7)?

Ethyl 1-methyl-4-piperidinecarboxylate (CAS: 24252-37-7) is primarily used in pharmaceuticals and fine chemicals. It serves as a key intermediate in the synthesis of various drugs and pharmaceuticals, as well as in the production of polymers and sensors due to its unique chemical properties.

What precautions should be taken when handling Ethyl 1-methyl-4-piperidinecarboxylate (CAS: 24252-37-7)?

When handling Ethyl 1-methyl-4-piperidinecarboxylate (CAS: 24252-37-7), it is important to wear appropriate personal protective equipment (PPE), including gloves, safety goggles, and a lab coat. The compound should be stored in a cool, dry place, away from heat sources and oxidizers. In case of a spill, it should be cleaned up using appropriate absorbents and disposed of according to local regulations. Always consult the Safety Data Sheet (SDS) for detailed handling and disposal information.