3,3',5,5'-Tetraisopropyl-4,4'-biphenyldiol

Basic Information

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CAS Number

2416-95-7

Molecular Formula

C24H34O2

Molecular Weight

354.53 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Hydrocarbons

Basic Physical Properties

Melting Point

107.0 to 111.0 deg-C

Boiling Point

451.9±45.0 °C at 760 mmHg

Flash Point

190.7±23.3 °C

Solubility

Insuluble (5.0E-4 g/L) (25 ºC),

SMILES

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CC(C)C1=CC(=CC(=C1O)C(C)C)C2=CC(=C(C(=C2)C(C)C)O)C(C)C

InChI

InChI=1S/C24H34O2/c1-13(2)19-9-17(10-20(14(3)4)23(19)25)18-11-21(15(5)6)24(26)22(12-18)16(7)8/h9-16,25-26H,1-8H3

InChIKey

QAISRHCMPQROAX-UHFFFAOYSA-N

LogP

7.258400000000007

Topological Polar Surface Area

40.46 Å²

Hydrogen Bond Donor/Acceptor

2 / 2

Complexity

352

Synonyms & References

English

2,2',6,6'-Tetraisopropyl-p,p'-biphenol
4-[4-hydroxy-3,5-di(propan-2-yl)phenyl]-2,6-di(propan-2-yl)phenol
A900714
SCHEMBL275427
(1,1'-Biphenyl)-4,4'-diol, 3,3',5,5'-tetrakis(1-methylethyl)-
2416-95-7
MFCD20257818
AKOS015999149
SY112771
D5281
di(2,6-diisopropylphenol)
UNII-H9GE6HX42A
3,3',5,5'-Tetrakis(1-methylethyl)biphenyl-4,4'-diol
Q27279805
F12840
3,3 inverted exclamation mark ,5,5 inverted exclamation mark -Tetraisopropylbiphenyl-4,4 inverted exclamation mark -diol
H9GE6HX42A
Propofol specified impurity E [EP]
3,3',5,5'-Tetraisopropyl-4,4'-dihydroxybiphenyl
AM20030426
3,3',5,5'-Tetraisopropylbiphenyl-4,4'-diol
DS-15761
CHEMBL478518
CS-0154315
3,3',5,5'-Tetraisopropyl-[1,1'-biphenyl]-4,4'-diol
DTXSID30178867
PROPOFOL IMPURITY E [EP IMPURITY]
BCP33602
BDBM50266965
Propofol Impurity E
Dipropofol

MDL Number

MFCD20257818

Customs Code

2907299090

FAQ

What are the physical and chemical properties of 3,3',5,5'-Tetraisopropyl-4,4'-biphenyldiol (CAS: 2416-95-7)?

3,3',5,5'-Tetraisopropyl-4,4'-biphenyldiol is a white crystalline solid with a high molecular weight. It has low water solubility but good solubility in organic solvents like dichloromethane and toluene. This compound is relatively stable but can react with strong acids and bases. Its molecular weight is approximately 438.6 g/mol.

How is 3,3',5,5'-Tetraisopropyl-4,4'-biphenyldiol (CAS: 2416-95-7) typically synthesized?

3,3',5,5'-Tetraisopropyl-4,4'-biphenyldiol is commonly synthesized via a two-step process. First, isopropyl bromide is coupled to 4,4'-dibromobiphenyl to form the corresponding diiodide. Then, the diiodide is reacted with sodium hydride to generate the desired diol. This method provides good yield and suitable selectivity.

What industries use 3,3',5,5'-Tetraisopropyl-4,4'-biphenyldiol (CAS: 2416-95-7)?

3,3',5,5'-Tetraisopropyl-4,4'-biphenyldiol is used in the pharmaceutical industry for the synthesis of certain drug intermediates. It also finds applications in the polymer industry as a monomer for the production of special plastics. Additionally, it is utilized in the semiconductor industry for manufacturing photoresists and in sensors for detecting specific chemical species.

What precautions should be taken when handling 3,3',5,5'-Tetraisopropyl-4,4'-biphenyldiol (CAS: 2416-95-7)?

When handling 3,3',5,5'-Tetraisopropyl-4,4'-biphenyldiol, it is essential to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood. In case of spillage, use appropriate spill cleanup materials and ensure proper disposal according to safety data sheet (SDS) guidelines.