3,5-Bis(benzyloxy)benzyl Bromide

Basic Information

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CAS Number

24131-32-6

Molecular Formula

C21H19BrO2

Molecular Weight

383.29 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Ethers

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Melting Point

85.0 to 89.0 deg-C

Boiling Point

504.3°C at 760 mmHg

Flash Point

209.8°C

Solubility

Insuluble (7.7E-4 g/L) (25 ºC),

Refractive Index

1.619

Vapor Pressure

0.0±1.2 mmHg at 25°C

SMILES

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C1=CC=C(C=C1)COC2=CC(=CC(=C2)CBr)OCC3=CC=CC=C3

InChI

InChI=1S/C21H19BrO2/c22-14-19-11-20(23-15-17-7-3-1-4-8-17)13-21(12-19)24-16-18-9-5-2-6-10-18/h1-13H,14-16H2

InChIKey

WGMYJGAUAQXYFQ-UHFFFAOYSA-N

LogP

5.739500000000004

Topological Polar Surface Area

18.46 Å²

Hydrogen Bond Donor/Acceptor

0 / 2

Complexity

307

Safety Information

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GHS Hazard Pictograms

H314

Hazard Statement

H314 Causes severe skin burns and eye damage
Skin corrosion/irritation

Hazard Class

Class IRRITANT Class IRRITANT

Synonyms & References

English

3,5-Dibenzyloxybenzyl Bromide
A817112
SCHEMBL4825449
AKOS015839495
1,3-Dibenzyloxy-5-(bromomethyl)benzene
B2093
1-(bromomethyl)-3, 5-bis(phenylmethoxy)benzene
(5-(bromomethyl)-1,3-phenylene)bis(oxy)bis(methylene)dibenzene
24131-32-6
3,5-Dibenzyloxy-alpha-bromotoluene
(((5-(Bromomethyl)-1,3-phenylene)bis(oxy))bis(methylene))dibenzene
MFCD02093444
FT-0638398
CS-0435425
1,3-bis(benzyloxy)-5-(bromomethyl)benzene
T70622
DTXSID00375482
3,5-bis(benzyloxy)benzyl bromide aka 3,5-dibenzyloxybenzyl bromide aka 3,5-dibenzyloxy-a-bromotoluene
1-(bromomethyl)-3,5-bis(phenylmethoxy)benzene
3,5-Dibenzyloxybenzyl Bromide, 98%
BS-23019
3,5-Bis(benzyloxy)benzyl Bromide
Benzene,1-(bromomethyl)-3,5-bis(phenylmethoxy)-
3,5-Bis(benzyloxy)benzyl bromide
1,3-bis-benzyloxy-5-bromomethylbenzene
3,5-Dibenzyloxy-α-bromotoluene
PubChem15063
3,5-Dibenzyloxybromobenzyl
VZ25635
FCH2713398

MDL Number

MFCD02093444

Customs Code

2909309090

FAQ

What are the physical and chemical properties of 3,5-Bis(benzyloxy)benzyl Bromide (CAS: 24131-32-6)?

3,5-Bis(benzyloxy)benzyl Bromide (CAS: 24131-32-6) has a crystalline form with a molecular weight of approximately 362.29 g/mol. It is poorly soluble in water but soluble in organic solvents like ethanol and acetone. Chemically, it is a bromide that can undergo nucleophilic substitution reactions with good reactivity. It has a low boiling point and decomposes above 100°C.

How is 3,5-Bis(benzyloxy)benzyl Bromide (CAS: 24131-32-6) typically synthesized?

3,5-Bis(benzyloxy)benzyl Bromide (CAS: 24131-32-6) is typically synthesized via a multistep reaction involving the first protection of the phenolic hydroxyl groups with benzyl bromide followed by a subsequent bromination step using N-bromosuccinimide (NBS) as the brominating agent. The reaction conditions include the use of a suitable catalyst like benzoyl peroxide to improve the yield and selectivity.

What industries use 3,5-Bis(benzyloxy)benzyl Bromide (CAS: 24131-32-6)?

3,5-Bis(benzyloxy)benzyl Bromide (CAS: 24131-32-6) is used in the pharmaceutical industry for the synthesis of various drugs, particularly those requiring protection of phenolic groups. It is also utilized in the polymer industry as a monomer for the production of special polymers. Additionally, it finds applications in the sensor and semiconductor industries due to its reactivity and stability.

What precautions should be taken when handling 3,5-Bis(benzyloxy)benzyl Bromide (CAS: 24131-32-6)?

When handling 3,5-Bis(benzyloxy)benzyl Bromide (CAS: 24131-32-6), it is essential to use appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Always ensure the use of a fume hood to minimize exposure. Spills should be cleaned up carefully using appropriate materials. Refer to the Safety Data Sheet (SDS) for detailed guidelines on safe handling and storage.