4-Piperidinecarbonitrile hydrochloride (1:1)

Basic Information

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CAS Number

240401-22-3

Molecular Formula

C6H11ClN2

Molecular Weight

53.49 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Nitriles

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

Physical State

White to Yellow Solid

Melting Point

201-204 °C

SMILES

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C1CNCCC1C#N.Cl

InChI

InChI=1S/C6H10N2.ClH/c7-5-6-1-3-8-4-2-6;/h6,8H,1-4H2;1H

InChIKey

PKMPMUHWHIIFBJ-UHFFFAOYSA-N

LogP

0.5838

Topological Polar Surface Area

35.0 Å²

Hydrogen Bond Donor/Acceptor

3 / 1

Complexity

105

Safety Information

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Hazard Statement

H301 Toxic if swallowed
Acute toxicity, oral

H319 Causes serious eye irritation
Serious eye damage/eye irritation

Synonyms & References

English

DTXSID30628014
Piperidine-4-carbonitrile--hydrogen chloride (1/1)
piperidine-4-carbonitrile hydrochloride
4-Cyanopiperidine (hydrochloride)
MFCD09037930
AMY4410
4-Piperidinecarbonitrile, monohydrochloride
piperidine-4-carbonitrilehydrochloride
Z969559998
4-cyanopiperidine hydrochloride salt
DS-16665
240401-22-3
4-Piperidinecarbonitrile, hydrochloride (1:1)
4-cyanopiperidinium chloride
piperidine-4-carbonitrile HCl
F0001-0823
CS-0019876
4-piperidinecarbonitrile hydrochloride
SY002496
FT-0692578
4-Cyano-piperidine hydrochloride
M7HMB74PLS
4-CYANOPIPERIDINE HYDROCHLORIDE
piperidine-4-carbonitrile;hydrochloride
SCHEMBL1513767
PKMPMUHWHIIFBJ-UHFFFAOYSA-N
A848574
4-cyanopiperidine HCl
SB10223
PIPERIDINE-4-CARBONITRILE, HCL
EN300-60120

MDL Number

MFCD09037930

Customs Code

2933399090

FAQ

What are the physical and chemical properties of 4-Piperidinecarbonitrile hydrochloride (CAS: 240401-22-3)?

4-Piperidinecarbonitrile hydrochloride is a white crystalline solid with a molecular weight of 214.64 g/mol. It has a solubility of 0.9 g/L in water and a high solubility in polar solvents like DMF and DMSO. Chemically, it reacts with nucleophiles, forming stable intermediates. It is stable under normal conditions but requires protection from moisture and light.

How is 4-Piperidinecarbonitrile hydrochloride (CAS: 240401-22-3) typically synthesized?

4-Piperidinecarbonitrile hydrochloride is synthesized by the reaction of 4-piperidinemethanone with hydrochloric acid. The reaction is carried out in an acidic medium, and the product is obtained in good yield. The process involves the formation of an intermediate nitrile which is then protonated to form the hydrochloride salt.

What industries use 4-Piperidinecarbonitrile hydrochloride (CAS: 240401-22-3)?

4-Piperidinecarbonitrile hydrochloride is primarily used in pharmaceuticals for the synthesis of certain active pharmaceutical ingredients. It is also used in the production of polymers and sensors due to its functional groups. Its applications in semiconductors are limited but it can be used as a precursor in some organic semiconductor materials.

What precautions should be taken when handling 4-Piperidinecarbonitrile hydrochloride (CAS: 240401-22-3)?

When handling 4-Piperidinecarbonitrile hydrochloride, use appropriate personal protective equipment (PPE) including gloves and safety glasses. Store in a cool, dry place away from moisture and light. Dispose of waste according to local regulations. Always refer to the Safety Data Sheet (SDS) for detailed safety information and emergency procedures.