2,2,6,6-Tetramethyl-4-piperidinol

Basic Information

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CAS Number

2403-88-5

Molecular Formula

C9H19NO

Molecular Weight

157.26 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

Melting Point

130.0 to 133.0 deg-C

Boiling Point

212-215 °C

Water Solubility

130 g/L (23 ºC)

Flash Point

212-215°C

Solubility

methanol: 0.1 g/mL, clear

Refractive Index

1.4248 (estimate)

SMILES

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CC1(CC(CC(N1)(C)C)O)C

InChI

InChI=1S/C9H19NO/c1-8(2)5-7(11)6-9(3,4)10-8/h7,10-11H,5-6H2,1-4H3

InChIKey

VDVUCLWJZJHFAV-UHFFFAOYSA-N

LogP

1.2878999999999998

Topological Polar Surface Area

32.26 Å²

Hydrogen Bond Donor/Acceptor

2 / 2

Complexity

136

Safety Information

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Hazard Statement

H314 Causes severe skin burns and eye damage
Skin corrosion/irritation

H317 May cause an allergic skin reaction
Sensitization, Skin

H336 May cause drowsiness or dizziness
Specific target organ toxicity, single exposure; Narcotic effects

H361 Suspected of damaging fertility or the unborn child
Reproductive toxicity

H373 Causes damage to organs through prolonged or repeated exposure
Specific target organ toxicity, repeated exposure

Hazard Class

Class 8 Class 8

Synonyms & References

English

DTXCID609655
NCGC00248548-01
2, 2, 6, 6-tetramethyl-4-hydroxypiperidine
W-109134
2,2,6,6-Tetramethyl-4-piperidinol, 98%
2,2,6,6-Tetramethyl-4-hydroxypiperidine
UNII-IS23Q8EGZ6
CHEMBL117625
NSC 16575
FT-0609127
SB41078
2,6,6-Tetramethyl-4-hydroxypiperidine
Lastar A
2403-88-5
DTXSID3029655
PS-5856
2,2,6,6-Tetramethyl-4-piperidinol
IS23Q8EGZ6
2,2,6,6-tetramethyl-piperidin-4ol
4-Hydroxy-2,6,6-tetramethylpiperidine
CS-0059143
AE-562/40209651
NCGC00257719-01
SCHEMBL38638
CAS-2403-88-5
NSC16575
4-Piperidinol, 2,2,6,6-tetramethyl-
AKOS000119836
EN300-19570
Q27280873
AM84816

MDL Number

MFCD00005983

Customs Code

29333999

FAQ

What is 2,2,6,6-Tetramethyl-4-piperidinol (CAS: 2403-88-5)?

2,2,6,6-Tetramethyl-4-piperidinol, with the CAS number 2403-88-5, is a piperidine derivative characterized by its four methyl groups attached to the piperidine ring. It is a white crystalline solid with a molecular formula of C9H19NO and is known for its stability and low reactivity. This compound is often used as a building block in organic synthesis due to its structural versatility and functional group compatibility.

What are the main uses of 2,2,6,6-Tetramethyl-4-piperidinol (CAS: 2403-88-5)?

2,2,6,6-Tetramethyl-4-piperidinol is primarily used in the pharmaceutical industry for the synthesis of various drugs and as a chiral auxiliary. It also finds applications in research for developing new chemical compounds and in industrial settings as a stabilizer or intermediate. Its utility in organic chemistry is due to its ability to participate in multiple reaction pathways and provide stereochemical control.

Is 2,2,6,6-Tetramethyl-4-piperidinol (CAS: 2403-88-5) safe?

2,2,6,6-Tetramethyl-4-piperidinol is generally considered safe when handled properly. It has low toxicity and is not classified as a hazardous substance under standard safety regulations. However, as with any chemical, it should be handled with care, using appropriate personal protective equipment (PPE) such as gloves and goggles. Proper ventilation and adherence to safety guidelines are recommended during use and storage.

How should 2,2,6,6-Tetramethyl-4-piperidinol (CAS: 2403-88-5) be stored?

2,2,6,6-Tetramethyl-4-piperidinol should be stored in a cool, dry, and well-ventilated area away from direct light. It is typically kept in a sealed container to prevent moisture absorption and maintain its chemical stability. Storage conditions should be below 25°C with low humidity to avoid degradation. Always ensure proper labeling and follow chemical storage guidelines to ensure safety and longevity.