Disodium (11beta,16alpha)-9-fluoro-11,17-dihydroxy-16-methyl-3,20-dioxopregna-1,4-dien-21-yl phosphate

Basic Information

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CAS Number

2392-39-4

Molecular Formula

C22H28FNa2O8P

Molecular Weight

516.4 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ketones

Fine Chemicals Surfactants Anionic Surfactants

Fine Chemicals Specialty Chemicals UV Stabilizers

Agricultural Chemicals Pesticides Insecticides

Polymers and Plastics Thermoplastics Polyolefins

Basic Physical Properties

Physical State

Powder

Melting Point

235°C(dec.)

Boiling Point

568.2°C at 760 mmHg

Density

1.3200

Water Solubility

Soluble in water. Slightly soluble in ethanol. Insoluble in dichloromethane.

Flash Point

No data available

Solubility

H2O: 50 mg/mL, clear, faintly yellow

Vapor Pressure

No data available

Specific Rotation

+74° (c=1, H2O)

SMILES

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CC1CC2C3CCC4=CC(=O)C=CC4(C3(C(CC2(C1(C(=O)COP(=O)([O-])[O-])O)C)O)F)C.[Na+].[Na+]

InChI

InChI=1S/C22H30FO8P.2Na/c1-12-8-16-15-5-4-13-9-14(24)6-7-19(13,2)21(15,23)17(25)10-20(16,3)22(12,27)18(26)11-31-32(28,29)30;;/h6-7,9,12,15-17,25,27H,4-5,8,10-11H2,1-3H3,(H2,28,29,30);;/q;2*+1/p-2/t12-,15+,16+,17+,19+,20+,21+,22+;;/m1../s1

InChIKey

PLCQGRYPOISRTQ-FCJDYXGNSA-L

LogP

2.88910

Complexity

962

Safety Information

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GHS Hazard Pictograms

H302

H351

H361

Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H351 Suspected of causing cancer
Carcinogenicity

H361 Suspected of damaging fertility or the unborn child
Reproductive toxicity

Synonyms & References

English

Dexamethasone sodium phosphate, European Pharmacopoeia (EP) Reference Standard
PLCQGRYPOISRTQ-FCJDYXGNSA-L
NS00083368
DEXAMETHASONE SODIUM PHOSPHATE [JAN]
NCGC00256783-01
Maxidex Ointment
A816989
Cebedex
Dexamethasone phosphate disodium
Dexair
2392-39-4
Dexium-SP
D00975
Dexamethasone disodium phosphate
Ak-Dex
CHEMBL2021430
Viadox
Spersadox
Dexagel
MAS CARE-PAK DEXAMETHASONE
Q27106391
DEXAMETHASONE 21-PHOSPHATE DISODIUM SALT [MI]
A830522
Colvasone
Dexaject SP
AC-17992
AI9376Y64P
Dexamethasone sodium phosphate for peak identification, European Pharmacopoeia (EP) Reference Standard
Disodium dexamethasone phosphate
disodium 9-fluoro-11beta,17-dihydroxy-16alpha-methyl-3,20-dioxopregna-1,4-dien-21-yl phosphate
DEXAMETHASONE SODIUM PHOSPHATE (USP IMPURITY)

MDL Number

MFCD00079105

Customs Code

2937290090

FAQ

What is Disodium (11beta,16alpha)-9-fluoro-11,17-dihydroxy-16-methyl-3,20-dioxopregna-1,4-dien-21-yl phosphate (CAS: 2392-39-4)?

Disodium (11beta,16alpha)-9-fluoro-11,17-dihydroxy-16-methyl-3,20-dioxopregna-1,4-dien-21-yl phosphate (CAS: 2392-39-4) is a steroid phosphate ester compound. It contains a fluoro group at the 9th position, hydroxyl groups at 11beta and 17alpha, and a methyl group at 16alpha. The molecule includes a phosphate group attached to the steroid backbone, making it relevant in pharmaceutical research. Its exact chemical formula and molecular weight are not specified in the provided data.

What are the main uses of Disodium (11beta,16alpha)-9-fluoro-11,17-dihydroxy-16-methyl-3,20-dioxopregna-1,4-dien-21-yl phosphate (CAS: 2392-39-4)?

This compound is primarily used in pharmaceutical research as a potential drug candidate, particularly in endocrinology and hormone-related therapies. It may also serve as an intermediate in the synthesis of steroid derivatives. Due to its complex structure, it is of interest in biochemical studies and may have applications in medicinal chemistry for developing new therapeutic agents.

Is Disodium (11beta,16alpha)-9-fluoro-11,17-dihydroxy-16-methyl-3,20-dioxopregna-1,4-dien-21-yl phosphate (CAS: 2392-39-4) safe?

Safety data for this compound is not widely available in public databases. As a phosphate ester, it may require standard laboratory safety precautions, including protective gloves, goggles, and ventilation. Handling should be done with care to avoid exposure, and compliance with OSHA and EPA guidelines is recommended. Specific toxicity profiles should be confirmed through specialized toxicological studies.

How should Disodium (11beta,16alpha)-9-fluoro-11,17-dihydroxy-16-methyl-3,20-dioxopregna-1,4-dien-21-yl phosphate (CAS: 2392-39-4) be stored?

This compound should be stored in a cool, dry, and dark environment to maintain stability. Keep in a sealed container to prevent moisture absorption and contamination. Avoid exposure to heat and direct light, as these can degrade the phosphate ester functionality. Storage conditions should be controlled to ensure long-term integrity, with specific requirements potentially outlined in safety data sheets (SDS).