2-(2-Naphthyl)-1H-indole

Basic Information

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CAS Number

23746-81-8

Molecular Formula

C18H13N

Molecular Weight

243.31 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

Melting Point

202.0 to 206.0 deg-C

Boiling Point

469.5°Cat760mmHg

Density

1.208

Flash Point

211.3°C

Solubility

Soluble in DMSO.

Refractive Index

1.737

SMILES

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C1=CC=C2C=C(C=CC2=C1)C3=CC4=CC=CC=C4N3

InChI

InChI=1S/C18H13N/c1-2-6-14-11-16(10-9-13(14)5-1)18-12-15-7-3-4-8-17(15)19-18/h1-12,19H

InChIKey

CACDYUNTCMPDMI-UHFFFAOYSA-N

LogP

4.988100000000003

Topological Polar Surface Area

15.79 Å²

Hydrogen Bond Donor/Acceptor

1 / 1

Complexity

313

Synonyms & References

English

DTXSID70295300
CCG-380
MFCD00124144
2-naphthalen-2-yl-1H-indole
PS-7541
2-(2-Naphthyl)indole
2-(2-naphthyl)-1h-indole
2-(2-Indolyl)naphthalene
SCHEMBL4109053
2-(2-naphthyl)-indol
AKOS005402809
CACDYUNTCMPDMI-UHFFFAOYSA-N
Maybridge1_005904
N0859
T72128
CHEMBL4536841
2-(naphthalen-2-yl)-1H-indole
2-(Naphth-2-yl)-1H-indole
NSC101079
FT-0608496
YAA74681
23746-81-8
CS-0095696
A816882
Z3226114573
NSC-101079
NCIOpen2_006768
HMS558E08
2-(2-naphthyl)-1H-indole
2-(Naphthalen-2-yl)indole
2-[2]naphthyl-indole

MDL Number

MFCD00124144

Customs Code

2933990090

FAQ

What are the physical and chemical properties of 2-(2-Naphthyl)-1H-indole (CAS: 23746-81-8)?

2-(2-Naphthyl)-1H-indole is a crystalline compound with a molecular weight of approximately 242.25 g/mol. It has a high solubility in organic solvents like dichloromethane and ethanol but is only slightly soluble in water. Chemically, it is moderately reactive towards electrophiles and nucleophiles, showing good stability under normal storage conditions.

How is 2-(2-Naphthyl)-1H-indole (CAS: 23746-81-8) typically synthesized?

2-(2-Naphthyl)-1H-indole is typically synthesized via a multistep process involving the reaction of 2-naphthol with an indole derivative. Common methods include use of Lewis acids as catalysts, such as aluminum chloride, to facilitate the coupling reaction. The overall yield is around 70-80%, with good selectivity towards the desired product.

What industries use 2-(2-Naphthyl)-1H-indole (CAS: 23746-81-8)?

2-(2-Naphthyl)-1H-indole is widely used in the pharmaceutical industry for the synthesis of various bioactive compounds. It is also employed in the polymer industry for the development of novel materials with specific properties. Additionally, it finds applications in sensor technology and semiconductor manufacturing due to its unique chemical structure.

What precautions should be taken when handling 2-(2-Naphthyl)-1H-indole (CAS: 23746-81-8)?

When handling 2-(2-Naphthyl)-1H-indole, it is important to use appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood to minimize exposure to vapors. Spills should be cleaned up immediately with caution, and proper safety data sheets (SDS) should be consulted for detailed handling instructions.