4-(Benzyloxy)-2-[bis(2-methyl-2-propanyl)phosphoryl]-3-(2-methyl-2-propanyl)-2,3-dihydro-1,3-benzoxaphosphole | CAS No. 2374143-30-1

4-(Benzyloxy)-2-[bis(2-methyl-2-propanyl)phosphoryl]-3-(2-methyl-2-propanyl)-2,3-dihydro-1,3-benzoxaphosphole

Basic Information

CAS Number

2374143-30-1

Molecular Formula

C26H38O3P2

Molecular Weight

460.54 g/mol

AD

Basic Physical Properties

CC(C)(C)P1C(OC2C=CC=C(OCC3C=CC=CC=3)C1=2)P(=O)(C(C)(C)C)C(C)(C)C

InChI

InChI=1S/C26H38O3P2/c1-24(2,3)30-22-20(28-18-19-14-11-10-12-15-19)16-13-17-21(22)29-23(30)31(27,25(4,5)6)26(7,8)9/h10-17,23H,18H2,1-9H3

InChIKey

GTKZLBRRROWCSC-UHFFFAOYSA-N

LogP

7.8074000000000074

Topological Polar Surface Area

35.53 Ų

Hydrogen Bond Donor/Acceptor

0 / 3

Complexity

631

Synonyms & References

English

  • ((2S,3S)-4-(benzyloxy)-3- (tert-butyl)-2,3- dihydrobenzo[d][1,3]oxaph osphol-2-yl)di-tert- butylphosphine oxide
  • ((2S,3S)-4-(benzyloxy)-3-(tert-butyl)-2,3-dihydrobenzo[d][1,3]oxaph osphol-2-yl)di-tert-butylphosphi

FAQ

What are the physical and chemical properties of 4-(Benzyloxy)-2-[bis(2-methyl-2-propanyl)phosphoryl]-3-(2-methyl-2-propanyl)-2,3-dihydro-1,3-benzoxaphosphole (CAS: 2374143-30-1)?

The compound has a crystalline form and a molecular weight of approximately 522.47 g/mol. It is poorly soluble in water but soluble in organic solvents such as dichloromethane and acetonitrile. The compound is reactive towards nucleophiles and can undergo phosphorus-nucleophile substitution reactions. It is stable under normal conditions but should be stored at room temperature away from moisture and light.

How is 4-(Benzyloxy)-2-[bis(2-methyl-2-propanyl)phosphoryl]-3-(2-methyl-2-propanyl)-2,3-dihydro-1,3-benzoxaphosphole (CAS: 2374143-30-1) typically synthesized?

The compound is typically synthesized via coupling of a benzyloxy phosphite with a 2-methyl-2-propanol derivative in the presence of a suitable catalyst such as triphenylphosphine. The reaction yields a product with high selectivity and good yield, making it a suitable method for its preparation.

What industries use 4-(Benzyloxy)-2-[bis(2-methyl-2-propanyl)phosphoryl]-3-(2-methyl-2-propanyl)-2,3-dihydro-1,3-benzoxaphosphole (CAS: 2374143-30-1)?

This compound is primarily used in the pharmaceutical industry for its potential as a phosphorus-based reagent. It is also explored for use in the development of sensors and as a building block in polymer chemistry due to its phosphorus-containing structure.

What precautions should be taken when handling 4-(Benzyloxy)-2-[bis(2-methyl-2-propanyl)phosphoryl]-3-(2-methyl-2-propanyl)-2,3-dihydro-1,3-benzoxaphosphole (CAS: 2374143-30-1)?

Handling should be done in a well-ventilated area or fume hood. Wear appropriate personal protective equipment, including gloves, goggles, and a lab coat. This compound is reactive and can release phosphorus-containing species. In case of spill or overexposure, refer to the Safety Data Sheet (SDS) for appropriate response procedures. Store the compound in a cool, dry place, away from moisture and heat sources.

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