6-Amino-2-pyridinecarboxylic acid

Basic Information

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CAS Number

23628-31-1

Molecular Formula

C6H6N2O2

Molecular Weight

138.13 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Basic Physical Properties

Physical State

Solid

Melting Point

315°C(dec.)

Boiling Point

387.8℃ at 760 mmHg

Water Solubility

Soluble in hot water.

Flash Point

188.3℃

SMILES

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C1=CC(=NC(=C1)N)C(=O)O

InChI

InChI=1S/C6H6N2O2/c7-5-3-1-2-4(8-5)6(9)10/h1-3H,(H2,7,8)(H,9,10)

InChIKey

NMCKJFCJIHCHIS-UHFFFAOYSA-N

LogP

0.3620000000000001

Topological Polar Surface Area

76.21 Å²

Hydrogen Bond Donor/Acceptor

3 / 4

Complexity

138

Safety Information

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GHS Hazard Pictograms

H315

H319

H335

Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Hazard Class

Class IRRITANT Class IRRITANT

Synonyms & References

English

6-Amino-pyridine-2-carboxylic acid
2-AMINO-6-PYRIDINECARBOXYLIC ACID
2-Pyridinecarboxylic acid, 6-amino-
NMCKJFCJIHCHIS-UHFFFAOYSA-N
CS-W002540
UNII-R6NBL985SU
HY-W002540
2-aminopyridine-6-carboxylic acid
MFCD00233711
2-amino-6-pyridine carboxylic acid
Z220336222
PS-4090
SY005202
FT-0638344
CL0230
SCHEMBL221380
AE-842/25003858
6-Aminopicolinic Acid
EN300-25970
6-AMINOPICOLINICACID
W-201991
6-Aminopyridine-2-carboxylic acid
AM20070248
6-Aminopyridine-2-carboxylicacid
NSC-522596
NSC522596
R6NBL985SU
PB23179
BDBM50121997
CHEMBL3322863
DTXSID90326004

MDL Number

MFCD00233711

Customs Code

2933399090

FAQ

What are the physical and chemical properties of 6-Amino-2-pyridinecarboxylic acid (CAS: 23628-31-1)?

6-Amino-2-pyridinecarboxylic acid (CAS: 23628-31-1) appears as a white to off-white crystalline solid. Its molecular weight is approximately 156.16 g/mol. The compound is moderately soluble in water and slightly soluble in ethanol. It is highly reactive owing to the amino group and carboxylic acid group, making it susceptible to hydrolysis and condensation reactions.

How is 6-Amino-2-pyridinecarboxylic acid (CAS: 23628-31-1) typically synthesized?

6-Amino-2-pyridinecarboxylic acid can be synthesized by treating 2-pyridinecarboxylic acid with an appropriate amine under basic conditions. Common methods include using ammonia or aniline, with sodium hydroxide as a catalyst. The reaction involves a nucleophilic substitution, leading to high selectivity and yield.

What industries use 6-Amino-2-pyridinecarboxylic acid (CAS: 23628-31-1)?

6-Amino-2-pyridinecarboxylic acid (CAS: 23628-31-1) is widely used in the pharmaceutical industry for the synthesis of bioactive compounds. It is also utilized in the polymer industry for the modification of polymers and in the sensor industry for the development of chemical sensors. Additionally, it finds applications in semiconductor manufacturing for surface treatments.

What precautions should be taken when handling 6-Amino-2-pyridinecarboxylic acid (CAS: 23628-31-1)?

When handling 6-Amino-2-pyridinecarboxylic acid (CAS: 23628-31-1), it is essential to use appropriate personal protective equipment (PPE), including gloves, goggles, and lab coats. The compound should be stored in a cool, dry place, away from moisture and oxidizing agents. In case of spill, it should be immediately cleaned up with appropriate absorbents. Always refer to the safety data sheet (SDS) for detailed handling instructions.