3-Fluoro-4-(Trifluoromethyl)-Benzylamine

Basic Information

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CAS Number

235106-09-9

Molecular Formula

C8H7F4N

Molecular Weight

193.14 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Amines

Fine Chemicals Specialty Chemicals UV Stabilizers

Agricultural Chemicals Pesticides Herbicides

Electronic Chemicals Semiconductor Materials Etchants

Basic Physical Properties

Refractive Index

1.453

SMILES

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C1=CC(=C(C=C1CN)F)C(F)(F)F

InChI

InChI=1S/C8H7F4N/c9-7-3-5(4-13)1-2-6(7)8(10,11)12/h1-3H,4,13H2

InChIKey

XYWYEOHNURYGGP-UHFFFAOYSA-N

LogP

2.3032000000000004

Topological Polar Surface Area

26.02 Å²

Hydrogen Bond Donor/Acceptor

2 / 1

Complexity

168

Safety Information

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Hazard Statement

Hazard Class

Class 8 Class 8

Sensitiveness

Air Sensitive

Synonyms & References

English

[3-fluoro-4-(trifluoromethyl)phenyl]methanamine
3-Fluoro-4-trifluoromethyl-benzylamine
EN300-1104808
AC-25952
FT-0615683
AKOS006228783
3-Fluoro-4-(trifluoromethyl)benzylamine
Benzenemethanamine, 3-fluoro-4-(trifluoromethyl)-
CS-0157090
SCHEMBL297408
s10416
MFCD00236287
3-fluoro-4-trifluoromethylbenzylamine
(3-fluoro-4-(trifluoromethyl)phenyl)methanamine
235106-09-9
PS-8323
A19831
3-Fluoro-4-(trifluoromethyl)benzylamine, AldrichCPR
DTXSID50372148

MDL Number

MFCD00236287

Customs Code

2921499090

FAQ

What are the physical and chemical properties of 3-Fluoro-4-(Trifluoromethyl)-Benzylamine (CAS: 235106-09-9)?

3-Fluoro-4-(Trifluoromethyl)-Benzylamine (CAS: 235106-09-9) is a white crystalline solid with a molecular weight of approximately 313.11 g/mol. It is poorly soluble in water but soluble in organic solvents like ethanol and acetonitrile. It reacts readily with nucleophiles. The compound is stable under normal conditions but should be stored away from moisture and heat.

How is 3-Fluoro-4-(Trifluoromethyl)-Benzylamine (CAS: 235106-09-9) typically synthesized?

3-Fluoro-4-(Trifluoromethyl)-Benzylamine is typically synthesized via the reduction of 3-fluoro-4-(trifluoromethyl)benzyl nitrile with a suitable reducing agent like sodium borohydride or lithium aluminum hydride. The reaction is carried out in an organic solvent like THF at low temperature. The yield is generally around 70-80%, with good selectivity.

What industries use 3-Fluoro-4-(Trifluoromethyl)-Benzylamine (CAS: 235106-09-9)?

3-Fluoro-4-(Trifluoromethyl)-Benzylamine (CAS: 235106-09-9) is used in the pharmaceutical industry for the synthesis of certain drugs, as well as in the polymer industry for developing novel materials. It also finds applications in the production of sensors and electronic devices due to its unique chemical properties.

What precautions should be taken when handling 3-Fluoro-4-(Trifluoromethyl)-Benzylamine (CAS: 235106-09-9)?

When handling 3-Fluoro-4-(Trifluoromethyl)-Benzylamine (CAS: 235106-09-9), it is important to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. It should be stored in a cool, dry place, away from direct sunlight and heat sources. Spills should be cleaned up with caution, following the guidelines in the safety data sheet (SDS). Fume hoods should be used during manipulation to minimize exposure.