Acetazolamide EP Impurity G

Basic Information

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CAS Number

2349-67-9

Molecular Formula

C2H3N3S2

Molecular Weight

133.2 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

Physical State

Powder

Melting Point

234°C(dec.)

Boiling Point

242.3°C at 760 mmHg

Flash Point

100.3℃

Solubility

2g/l

Refractive Index

1.5800 (estimate)

SMILES

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Nc1nnc(S)s1

InChI

InChI=1S/C2H3N3S2/c3-1-4-5-2(6)7-1/h(H2,3,4)(H,5,6)

InChIKey

GDGIVSREGUOIJZ-UHFFFAOYSA-N

LogP

0.409

Topological Polar Surface Area

51.8 Å²

Hydrogen Bond Donor/Acceptor

2 / 3

Complexity

129

Safety Information

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GHS Hazard Pictograms

H302

H315

H319

H335

Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

5-Amino-1,3,4-thiadiazole-2-thiol
2-Amino-5-mercapto-1,3,4-thiadiazole
AMT
5-Amino-1.3.4-thiadiazole-2-thiol
2-amino thiadiazole-5-thiol
2-AMino-5-Mercapto-1
2-Amino-5-mercapto-1,3,4-thiad
2-Amino-5-mercaptothiadiazole
2-amino-5-sulfanyl-1,3,4-thiadiazole
5-Amino-1,3,4-thiadi
5-amino-2-mercapto-1,3,4-thiadiazole
5-amino-3H-1,3,4-thiadiazole-2-thione
5-sulfanyl-1,3,4-thiadiazol-2-ylamine
EAMTD
usafpd-25
Acetazolamide Impurity G
1,3,4-Thiadiazole-2(3H)-thione, 5-amino-
5-Amino-1,3,4-thiadiazole-2(3H)-thione
2-AMINO-1,3,4-THIADIAZOLE-5-THIOL
2-Thiol-5-amino-1,3,4-thiadiazole
2-Mercapto-5-amino-1,3,4-thiadiazole
5-Amino-1,3,4-thiadiazoline-2-thione
1,3,4-Thiadiazole-2-thiol, 5-amino-
B1HEG7V21S
2-Amino-5-mercaptothiadi
5-amino-1,3,4-thiadiazole-2-thiol

MDL Number

MFCD00003108

Customs Code

29349990

FAQ

What is Acetazolamide EP Impurity G (CAS: 2349-67-9)?

Acetazolamide EP Impurity G (CAS: 2349-67-9) is a chemical compound classified as a sulfonamide derivative. It is an impurity commonly found in the synthesis or formulation of acetazolamide, a carbonic anhydrase inhibitor used in pharmaceuticals. The compound exhibits solubility in polar solvents and is typically characterized by its molecular structure and purity grade, making it relevant for quality control in drug manufacturing.

What are the main uses of Acetazolamide EP Impurity G (CAS: 2349-67-9)?

Acetazolamide EP Impurity G (CAS: 2349-67-9) is primarily used in pharmaceutical research to identify and quantify impurities in acetazolamide production. It also serves as a reference standard in analytical chemistry for testing drug purity. Additionally, it may be employed in industrial processes for chemical synthesis or in academic studies to explore the properties of sulfonamide derivatives.

Is Acetazolamide EP Impurity G (CAS: 2349-67-9) safe?

Acetazolamide EP Impurity G (CAS: 2349-67-9) is not intended for human or animal use but requires adherence to safety guidelines during handling. It may pose health risks if inhaled, ingested, or contacted with skin, so protective equipment like gloves and goggles is recommended. Proper disposal and storage are essential to comply with environmental and safety regulations.

How should Acetazolamide EP Impurity G (CAS: 2349-67-9) be stored?

Acetazolamide EP Impurity G (CAS: 2349-67-9) should be stored in a cool, dry place away from direct light. Keep in a tightly sealed container to prevent moisture absorption and contamination. Maintain storage conditions below 25°C and ensure humidity levels are low to preserve stability and prolong shelf life.