N-Hydroxy-5'-O-isobutyryl-2',3'-O-isopropylidene-3,4-dihydrocytidine | CAS No. 2346620-55-9

N-Hydroxy-5'-O-isobutyryl-2',3'-O-isopropylidene-3,4-dihydrocytidine

Basic Information

CAS Number

2346620-55-9

Molecular Formula

C16H23N3O7

Molecular Weight

369.37 g/mol

AD

Basic Physical Properties

Density

1.51±0.1 g/cm3(Predicted)

CC(C)C(OC[C@H]1O[C@@H](N(C(N/2)=O)C=CC2=N/O)[C@@]3([H])[C@]1([H])OC(C)(C)O3)=O

InChI

InChI=1S/C16H23N3O7/c1-8(2)14(20)23-7-9-11-12(26-16(3,4)25-11)13(24-9)19-6-5-10(18-22)17-15(19)21/h5-6,8-9,11-13,22H,7H2,1-4H3,(H,17,18,21)/t9-,11-,12-,13-/m1/s1

InChIKey

MNKXNZQOZRWRKB-OJAKKHQRSA-N

LogP

0.08300000000000152

pKa

8.16±0.20(Predicted)

Topological Polar Surface Area

124.37 Ų

Hydrogen Bond Donor/Acceptor

2 / 10

Synonyms & References

English

  • ((3aR,4R,6R,6aR)-6-((E)-4-(hydroxyimino)-2-oxo-3,4-dihydropyrimidin-1(2H)-yl)-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxol-4-yl)methyl isobutyrate
  • ((3aR,4R,6R,6aR)-6-(4-(hydroxyamino)-2-oxopyrimidin-1(2H)-yl)-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxol-4-yl)methyl isobutyrate
  • URIDINE,2',3'-O-(1-METHYLETHYLIDENE)-,4-OXIMEChemicalbook,5'-(2-METHYLPROPANOATE)
  • Molnupiravir n-1
  • ((3aR,4R,6R,6aR)-6-(4-(hydroxyamino)-2-oxopyrimidin-1(2H)-yl)-2,2-dimethyltetrahydrofuro[3,4-d][1,3
  • ((3aR,4R,6R,6aR)-6-(4-(hydroxyamino)-2-oxopyrimidin-1(2H)-yl)-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxol-4-yl)methyl
  • Molnupiravir Impurity 11
  • [(3aR,4R,6R,6aR)-6-[(Z)-4-(Hydroxyimino)-2-oxo-3,4-dihydropyrimidin-1(2H)-yl]-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxol-4-yl]methyl Isobutyrate
  • 2',3'-O-(1-Methylethylidene)uridine 4-Oxime 5'-(2-Methylpropanoate)

MDL Number

MFCD33549024

FAQ

What regulatory guidelines apply to N-Hydroxy-5'-O-isobutyryl-2',3'-O-isopropylidene-3,4-dihydrocytidine (CAS: 2346620-55-9)?

N-Hydroxy-5'-O-isobutyryl-2',3'-O-isopropylidene-3,4-dihydrocytidine (CAS: 2346620-55-9) falls under the scope of GHS classification, which categorizes it based on its hazards. For EU manufacturers and importers, REACH regulations mandate registration, assessment, and authorization. In the U.S., FDA and EPA regulations govern its handling and disposal. These regulations ensure safe use and disposal, minimizing environmental impact and workplace hazards.

Are there alternatives to N-Hydroxy-5'-O-isobutyryl-2',3'-O-isopropylidene-3,4-dihydrocytidine (CAS: 2346620-55-9) in synthesis?

N-Hydroxy-5'-O-isobutyryl-2',3'-O-isopropylidene-3,4-dihydrocytidine (CAS: 2346620-55-9) can be synthesized using various alternatives. For instance, 5'-O-acetyl analogs or 3',5'-di-O-isopropylidene derivatives can be used depending on the desired properties. Isomers such as 2',3'-O-isopropylidene-3,4-dihydrouridine may also be considered for specific applications. These alternatives provide flexibility in synthetic approaches.

What is the market or research trend for N-Hydroxy-5'-O-isobutyryl-2',3'-O-isopropylidene-3,4-dihydrocytidine (CAS: 2346620-55-9)?

The market for N-Hydroxy-5'-O-isobutyryl-2',3'-O-isopropylidene-3,4-dihydrocytidine (CAS: 2346620-55-9) is driven by its potential in pharmaceutical and biotechnological research. Recent trends indicate increased interest in its use as a prodrug for nucleosides. Research is focusing on its therapeutic applications, particularly in antiviral and anticancer treatments. Market demand is expected to grow as more studies validate its efficacy and safety.

How should waste containing N-Hydroxy-5'-O-isobutyryl-2',3'-O-isopropylidene-3,4-dihydrocytidine (CAS: 2346620-55-9) be handled?

Waste containing N-Hydroxy-5'-O-isobutyryl-2',3'-O-isopropylidene-3,4-dihydrocytidine (CAS: 2346620-55-9) should be collected in appropriate, leak-proof containers and stored in a secure, well-ventilated area. Upon disposal, it should be incinerated or treated by a professional waste disposal service to minimize environmental impact. Precautions include proper personal protective equipment (PPE) and adherence to local environmental regulations to prevent contamination of water and soil.

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