1,10-Phenanthrolin-4-ol

Basic Information

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CAS Number

23443-31-4

Molecular Formula

C12H8N2O

Molecular Weight

196.21 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

Melting Point

214-215 ºC

SMILES

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c1cc2ccc3c(ccnc3c2nc1)O

InChI

InChI=1S/C12H8N2O/c15-10-5-7-14-12-9(10)4-3-8-2-1-6-13-11(8)12/h1-7H,(H,14,15)

InChIKey

IZYBEGHUZQSYII-UHFFFAOYSA-N

LogP

2.4886000000000013

Topological Polar Surface Area

46.010000000000005 Å²

Hydrogen Bond Donor/Acceptor

1 / 3

Synonyms & References

English

1,10-Phenanthrolin-4-ol
1H-1,10-phenanthrolin-4-one
1H-[1,10]phenanthrolin-4-one
4-hydroxy-1,10-phenanthroline
HMS2211O18

MDL Number

MFCD00957343

Customs Code

2933990090

FAQ

What are the physical and chemical properties of 1,10-Phenanthrolin-4-ol (CAS: 23443-31-4)?

1,10-Phenanthrolin-4-ol (CAS: 23443-31-4) is a crystalline solid with a molecular weight of approximately 184.23 g/mol. It has a pKa of around 10.5, indicating basic properties. The compound is slightly soluble in water and has good solubility in organic solvents like ethanol and acetone. It exhibits moderate reactivity towards electrophiles and can be used in various chemical reactions.

How is 1,10-Phenanthrolin-4-ol (CAS: 23443-31-4) typically synthesized?

1,10-Phenanthrolin-4-ol is commonly synthesized through the reduction of 1,10-phenanthroline using a reducing agent like sodium borohydride. The reaction is carried out in a suitable solvent such as ethanol or methanol. The yield is generally around 90%, with high selectivity towards the alcohol functional group.

What industries use 1,10-Phenanthrolin-4-ol (CAS: 23443-31-4)?

1,10-Phenanthrolin-4-ol (CAS: 23443-31-4) is used in the pharmaceutical industry for its potential as a chelating agent and antioxidant. It is also utilized in the semiconductor industry as a dopant for organic semiconductors. Additionally, it has applications in the polymer industry for improving the properties of certain polymers and as a sensor material in analytical chemistry.

What precautions should be taken when handling 1,10-Phenanthrolin-4-ol (CAS: 23443-31-4)?

When handling 1,10-Phenanthrolin-4-ol (CAS: 23443-31-4), it is important to wear appropriate personal protective equipment (PPE) such as gloves, safety goggles, and a lab coat. This compound should be used in a fume hood to minimize inhalation risks. Spills should be cleaned up using appropriate absorbent materials, and the area should be well-ventilated. Always refer to the Safety Data Sheet (SDS) for detailed handling instructions and emergency procedures.